Two Sigma Investments’s Pfizer PFE Stock Holding History

Two Sigma Investments’s Portfolio PFE Stock Details PFE Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q1	$5.96M	Sell	212,100 -1,856,008	-90%	-$49.4M	﹤0.01%	1816
2025 Q4	$51.5M	Buy	2,068,108 +1,992,180	+2,624%	+$50.2M	0.07%	344
2025 Q3	$1.93M	Buy	+75,928	New	+$1.87M	﹤0.01%	2148
2025 Q2	–	Sell	-729,647	Closed	-$18.5M	–	3445
2025 Q1	$18.5M	Sell	729,647 -4,573,084	-86%	-$120M	0.04%	520
2024 Q4	$141M	Sell	5,302,731 -3,299,112	-38%	-$89.5M	0.31%	69
2024 Q3	$249M	Sell	8,601,843 -106,579	-1%	-$3.11M	0.55%	13
2024 Q2	$244M	Buy	8,708,422 +289,408	+3%	+$7.97M	0.56%	15
2024 Q1	$234M	Buy	+8,419,014	New	+$234M	0.55%	16
2023 Q4	–	Sell	-6,996,440	Closed	-$232M	–	3321
2023 Q3	$232M	Buy	6,996,440 +2,790,951	+66%	+$98.7M	0.62%	18
2023 Q2	$154M	Buy	4,205,489 +4,045,162	+2,523%	+$157M	0.39%	54
2023 Q1	$6.54M	Buy	+160,327	New	+$6.92M	0.02%	777
2022 Q4	–	Sell	-2,779,689	Closed	-$122M	–	3015
2022 Q3	$122M	Buy	+2,779,689	New	+$135M	0.41%	58
2022 Q1	–	Sell	-4,590,528	Closed	-$271M	–	3912
2021 Q4	$271M	Buy	+4,590,528	New	+$227M	0.58%	4
2021 Q3	–	Sell	-5,919,331	Closed	-$262M	–	4586
2021 Q2	$232M	Sell	5,919,331 -1,161,719	-16%	-$45.2M	0.53%	18
2021 Q1	$257M	Buy	+7,081,050	New	+$251M	0.67%	6
2020 Q4	–	Sell	-7,225,711	Closed	-$252M	–	3654
2020 Q3	$252M	Sell	7,225,711 -415,676	-5%	-$14.6M	0.89%	7
2020 Q2	$237M	Buy	7,641,387 +3,480,570	+84%	+$118M	1.17%	5
2020 Q1	$129M	Sell	4,160,817 -3,096,786	-43%	-$106M	1.05%	8
2019 Q4	$270M	Buy	7,257,603 +3,035,545	+72%	+$108M	0.81%	2
2019 Q3	$144M	Buy	4,222,058 +2,898,762	+219%	+$105M	0.48%	33
2019 Q2	$54.4M	Sell	1,323,296 -957,675	-42%	-$38M	0.18%	133
2019 Q1	$91.9M	Buy	2,280,971 +2,235,387	+4,904%	+$89.5M	0.3%	60
2018 Q4	$1.89M	Buy	45,584 +22,918	+101%	+$951K	0.01%	1269
2018 Q3	$948K	Buy	+22,666	New	+$873K	﹤0.01%	2015
2018 Q2	–	Sell	-4,661,767	Closed	-$159M	–	3562
2018 Q1	$157M	Sell	4,661,767 -440,014	-9%	-$15.1M	0.52%	13
2017 Q4	$175M	Buy	5,101,781 +1,434,589	+39%	+$48.9M	0.57%	6
2017 Q3	$124M	Buy	3,667,192 +1,631,266	+80%	+$52.4M	0.44%	45
2017 Q2	$64.9M	Sell	2,035,926 -432,163	-18%	-$13.6M	0.23%	103
2017 Q1	$80.1M	Buy	+2,468,089	New	+$77.8M	0.27%	70
2016 Q4	–	Sell	-2,702,032	Closed	-$82.5M	–	3427
2016 Q3	$86.8M	Buy	2,702,032 +1,286,649	+91%	+$43M	0.31%	64
2016 Q2	$47.3M	Sell	1,415,383 -4,552,699	-76%	-$145M	0.2%	109
2016 Q1	$168M	Buy	5,968,082 +2,361,051	+65%	+$67.4M	0.8%	7
2015 Q4	$110M	Buy	3,607,031 +364,359	+11%	+$11.5M	0.53%	29
2015 Q3	$96.6M	Buy	3,242,672 +3,196,718	+6,956%	+$102M	0.5%	46
2015 Q2	$1.46M	Buy	+45,954	New	+$1.5M	0.01%	1404
2015 Q1	–	Sell	-752,739	Closed	-$23.9M	–	2798
2014 Q4	$22.2M	Sell	752,739 -2,545,551	-77%	-$73M	0.12%	210
2014 Q3	$92.5M	Buy	3,298,290 +1,497,866	+83%	+$42M	0.41%	56
2014 Q2	$50.7M	Sell	1,800,424 -140,918	-7%	-$4.02M	0.23%	116
2014 Q1	$59.2M	Sell	1,941,342 -3,611,743	-65%	-$108M	0.32%	69
2013 Q4	$161M	Buy	5,553,085 +990,547	+22%	+$28.8M	0.89%	1
2013 Q3	$124M	Buy	+4,562,538	New	+$124M	0.79%	12

Other funds holding PFE

BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return

VCM

Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM

State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return

Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return

VPM

Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM

Fisher Asset Management Camas, Washington $295B AUM 31.6% 1-Year Est. Return

Morgan Stanley New York $1.66T AUM 25.57% 1-Year Est. Return

Northern Trust Chicago, Illinois $757B AUM 28.64% 1-Year Est. Return

Massachusetts Financial Services Boston, Massachusetts $298B AUM 21.96% 1-Year Est. Return

State Farm Mutual Automobile Insurance Bloomington, Illinois $127B AUM 32.55% 1-Year Est. Return

Two Sigma Investments's PFE Position: Q1 2026 in Review

Two Sigma Investments reduced its Pfizer (PFE) stake by 90% in Q1 2026, selling an estimated $49.4M and leaving 212,100 shares worth $5.96M. The position accounts for ﹤0.01% of the portfolio, ranked #1816.

Two Sigma Investments first reported a position in PFE in Q3 2013 and has held it in 41 quarters since. The position peaked at $271M in Q4 2021. 2,936 funds tracked by Wall St. Rank hold PFE as of Q1 2026.

Two Sigma Investments held 212,100 shares of Pfizer worth $5.96M as of Q1 2026.
Two Sigma Investments sold 1,856,008 Pfizer shares in Q1 2026, an estimated $49.4M.
Pfizer made up ﹤0.01% of Two Sigma Investments's portfolio in Q1 2026, its #1816 holding.
Two Sigma Investments first reported a position in Pfizer in Q3 2013 and has held it in 41 quarters since.
Two Sigma Investments's Pfizer position peaked at $271M in Q4 2021.
2,936 funds tracked by Wall St. Rank held Pfizer as of Q1 2026.

Based on Two Sigma Investments's 13F filing for Q1 2026, filed 15 May 2026.