Two Sigma Investments
OSTX

Two Sigma Investments’s OS Therapies Inc OSTX Stock Holding History

Two Sigma Investments’s Portfolio OSTX Stock Details OSTX Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$37.2K Sell
26,380
-61,157
-70% -$86.8K ﹤0.01% 4480
2025
Q4 		$123K Buy
87,537
+1,290
+1% +$2.33K ﹤0.01% 3840
2025
Q3 		$169K Buy
+86,247
New +$171K ﹤0.01% 3407

Other funds holding OSTX

VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
Susquehanna International Group
Susquehanna International Group Bala Cynwyd, Pennsylvania $893B AUM 36.07% 1-Year Est. Return
CM
CM Management Gulf Breeze, Florida $120M AUM 37.12% 1-Year Est. Return
UBS Group
UBS Group Zurich, Switzerland $666B AUM 30.12% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
HFS
Howard Financial Services Dallas, Texas $1B AUM 20.02% 1-Year Est. Return
VFT
Vanguard Fiduciary Trust Malvern, Pennsylvania $396B AUM
State Street
State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return
Northern Trust
Northern Trust Chicago, Illinois $757B AUM 28.64% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return

Two Sigma Investments's OSTX Position: Q1 2026 in Review

Two Sigma Investments reduced its OS Therapies Inc (OSTX) stake by 70% in Q1 2026, selling an estimated $86.8K and leaving 26,380 shares worth $37.2K. The position accounts for ﹤0.01% of the portfolio, ranked #4480.

Two Sigma Investments first reported a position in OSTX in Q3 2025 and has held it in 3 quarters since. The position peaked at $169K in Q3 2025. 29 funds tracked by Wall St. Rank hold OSTX as of Q1 2026.

  • Two Sigma Investments held 26,380 shares of OS Therapies Inc worth $37.2K as of Q1 2026.
  • Two Sigma Investments sold 61,157 OS Therapies Inc shares in Q1 2026, an estimated $86.8K.
  • OS Therapies Inc made up ﹤0.01% of Two Sigma Investments's portfolio in Q1 2026, its #4480 holding.
  • Two Sigma Investments first reported a position in OS Therapies Inc in Q3 2025 and has held it in 3 quarters since.
  • Two Sigma Investments's OS Therapies Inc position peaked at $169K in Q3 2025.
  • 29 funds tracked by Wall St. Rank held OS Therapies Inc as of Q1 2026.

Based on Two Sigma Investments's 13F filing for Q1 2026, filed 15 May 2026.