Two Sigma Investments
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Two Sigma Investments’s Outset Medical OM Stock Holding History

Two Sigma Investments’s Portfolio OM Stock Details OM Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q4 		– Sell
-146,598
Closed -$2.07M – 4312
2025
Q3 		$2.07M Buy
146,598
+72,504
+98% +$1.13M ﹤0.01% 2103
2025
Q2 		$1.42M Buy
74,094
+57,806
+355% +$902K ﹤0.01% 2048
2025
Q1 		$180K Sell
16,288
-16,285
-50% -$194K ﹤0.01% 2874
2024
Q4 		$542K Buy
32,573
+8,622
+36% +$108K ﹤0.01% 2500
2024
Q3 		$243K Buy
23,951
+12,847
+116% +$382K ﹤0.01% 2749
2024
Q2 		$641K Sell
11,104
-29,422
-73% -$1.44M ﹤0.01% 2238
2024
Q1 		$1.35M Buy
40,526
+15,682
+63% +$794K ﹤0.01% 1760
2023
Q4 		$2.02M Buy
24,844
+22,538
+977% +$1.83M ﹤0.01% 1538
2023
Q3 		$376K Sell
2,306
-15,784
-87% -$3.73M ﹤0.01% 2401
2023
Q2 		$5.93M Sell
18,090
-629
-3% -$192K 0.01% 852
2023
Q1 		$5.17M Buy
+18,719
New +$6.87M 0.01% 890
2022
Q3 		– Sell
-9,229
Closed -$2.06M – 2712
2022
Q2 		$2.06M Buy
+9,229
New +$3.97M 0.01% 1189
2021
Q4 		– Sell
-2,148
Closed -$1.59M – 4697
2021
Q3 		$1.59M Buy
+2,148
New +$1.46M ﹤0.01% 2192
2021
Q2 		– Sell
-746
Closed -$608K – 4432
2021
Q1 		$608K Buy
+746
New +$576K ﹤0.01% 2745

Other funds holding OM

Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
Alyeska Investment Group
Alyeska Investment Group Chicago, Illinois $35.4B AUM 33.54% 1-Year Est. Return
WP
Woodline Partners San Francisco, California $26.4B AUM 44.85% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
Vanguard Group
Vanguard Group Malvern, Pennsylvania $6.9T AUM 27.45% 1-Year Est. Return
Bank of America
Bank of America Charlotte, North Carolina $1.37T AUM 24.88% 1-Year Est. Return
PA
Perceptive Advisors New York $5.12B AUM 314.02% 1-Year Est. Return
Ensign Peak Advisors
Ensign Peak Advisors Salt Lake City, Utah $53.7B AUM 29.47% 1-Year Est. Return
BCM
BML Capital Management Zionsville, Indiana $156M AUM 129.82% 1-Year Est. Return
PHS
PFM Health Sciences San Francisco, California $1.1B AUM 57.92% 1-Year Est. Return

Two Sigma Investments's OM Position: Q4 2025 in Review

Two Sigma Investments sold out of Outset Medical (OM) in Q4 2025, closing a stake of 146,598 shares — an estimated $2.07M sold.

Two Sigma Investments first reported a position in OM in Q1 2021 and held it in 14 quarters. The position peaked at $5.93M in Q2 2023. 100 funds tracked by Wall St. Rank hold OM as of Q4 2025.

  • Two Sigma Investments reported no remaining Outset Medical position as of Q4 2025 after selling out during the quarter.
  • Two Sigma Investments sold 146,598 Outset Medical shares in Q4 2025, an estimated $2.07M.
  • Two Sigma Investments first reported a position in Outset Medical in Q1 2021 and held it in 14 quarters.
  • Two Sigma Investments's Outset Medical position peaked at $5.93M in Q2 2023.
  • 100 funds tracked by Wall St. Rank held Outset Medical as of Q4 2025.

Based on Two Sigma Investments's 13F filing for Q4 2025, filed 17 Feb 2026.