Two Sigma Investments
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Two Sigma Investments’s MiMedx Group MDXG Stock Holding History

Two Sigma Investments’s Portfolio MDXG Stock Details MDXG Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$1.06M Buy
267,297
+48,362
+22% +$244K ﹤0.01% 3231
2025
Q4 		$1.48M Buy
218,935
+158,074
+260% +$1.11M ﹤0.01% 2671
2025
Q3 		$425K Sell
60,861
-42,021
-41% -$292K ﹤0.01% 3064
2025
Q2 		$629K Sell
102,882
-221,962
-68% -$1.48M ﹤0.01% 2481
2025
Q1 		$2.47M Sell
324,844
-71,063
-18% -$594K 0.01% 1606
2024
Q4 		$3.81M Sell
395,907
-92,228
-19% -$718K 0.01% 1272
2024
Q3 		$2.88M Sell
488,135
-151,906
-24% -$1.01M 0.01% 1439
2024
Q2 		$4.44M Sell
640,041
-113,699
-15% -$799K 0.01% 1062
2024
Q1 		$5.8M Buy
753,740
+133,677
+22% +$1.07M 0.01% 899
2023
Q4 		$5.44M Sell
620,063
-9,948
-2% -$72.8K 0.01% 945
2023
Q3 		$4.59M Buy
630,011
+146,615
+30% +$1.09M 0.01% 951
2023
Q2 		$3.2M Buy
483,396
+435,984
+920% +$2.22M 0.01% 1150
2023
Q1 		$162K Sell
47,412
-85,664
-64% -$332K ﹤0.01% 2601
2022
Q4 		$370K Sell
133,076
-5,049
-4% -$15.1K ﹤0.01% 2156
2022
Q3 		$396K Buy
138,125
+113,421
+459% +$403K ﹤0.01% 1875
2022
Q2 		$86K Sell
24,704
-173,235
-88% -$678K ﹤0.01% 2285
2022
Q1 		$932K Sell
197,939
-74,056
-27% -$362K ﹤0.01% 1737
2021
Q4 		$1.64M Buy
271,995
+255,795
+1,579% +$1.78M ﹤0.01% 2103
2021
Q3 		$98K Buy
+16,200
New +$183K ﹤0.01% 4084
2021
Q1 		– Sell
-44,751
Closed -$406K – 4085
2020
Q4 		$406K Buy
+44,751
New +$322K ﹤0.01% 2645
2018
Q4 		– Sell
-167,143
Closed -$1.03M – 3316
2018
Q3 		$1.03M Buy
167,143
+43,334
+35% +$196K ﹤0.01% 1955
2018
Q2 		$791K Sell
123,809
-192,376
-61% -$1.37M ﹤0.01% 2324
2018
Q1 		$2.2M Buy
316,185
+230,031
+267% +$2.68M 0.01% 1454
2017
Q4 		$1.09M Sell
86,154
-200,723
-70% -$2.45M ﹤0.01% 1911
2017
Q3 		$3.41M Sell
286,877
-772,639
-73% -$11.5M 0.01% 1001
2017
Q2 		$15.9M Buy
+1,059,516
New +$14.1M 0.06% 386
2016
Q2 		– Sell
-24,400
Closed -$213K – 3087
2016
Q1 		$213K Buy
+24,400
New +$203K ﹤0.01% 2562
2015
Q3 		– Sell
-348,118
Closed -$4.04M – 2507
2015
Q2 		$4.04M Buy
348,118
+241,098
+225% +$2.48M 0.02% 817
2015
Q1 		$1.11M Sell
107,020
-7,933
-7% -$74.2K 0.01% 1512
2014
Q4 		$1.32M Buy
+114,953
New +$1.14M 0.01% 1237
2014
Q2 		– Sell
-83,532
Closed -$512K – 2267
2014
Q1 		$512K Buy
+83,532
New +$614K ﹤0.01% 1469

Other funds holding MDXG

EWM
Essex Woodlands Management The Woodlands, Texas $251M AUM 13.72% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
TI
Trigran Investments Northbrook, Illinois $418M AUM 3.34% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
PCMI
Paradigm Capital Management Inc Albany, New York $2.61B AUM 78.58% 1-Year Est. Return
NCM
Nantahala Capital Management New Canaan, Connecticut $2.72B AUM 121.58% 1-Year Est. Return
Renaissance Technologies
Renaissance Technologies New York $63.9B AUM 45.56% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
FLAM
First Light Asset Management Edina, Minnesota $1.12B AUM 114.45% 1-Year Est. Return

Two Sigma Investments's MDXG Position: Q1 2026 in Review

Two Sigma Investments increased its MiMedx Group (MDXG) stake by 22% in Q1 2026, buying an estimated $244K and bringing the position to 267,297 shares worth $1.06M. The position accounts for ﹤0.01% of the portfolio, ranked #3231.

Two Sigma Investments first reported a position in MDXG in Q1 2014 and has held it in 31 quarters since. The position peaked at $15.9M in Q2 2017. 237 funds tracked by Wall St. Rank hold MDXG as of Q1 2026.

  • Two Sigma Investments held 267,297 shares of MiMedx Group worth $1.06M as of Q1 2026.
  • Two Sigma Investments bought 48,362 MiMedx Group shares in Q1 2026, an estimated $244K.
  • MiMedx Group made up ﹤0.01% of Two Sigma Investments's portfolio in Q1 2026, its #3231 holding.
  • Two Sigma Investments first reported a position in MiMedx Group in Q1 2014 and has held it in 31 quarters since.
  • Two Sigma Investments's MiMedx Group position peaked at $15.9M in Q2 2017.
  • 237 funds tracked by Wall St. Rank held MiMedx Group as of Q1 2026.

Based on Two Sigma Investments's 13F filing for Q1 2026, filed 15 May 2026.