Two Sigma Investments
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Two Sigma Investments’s Ligand Pharmaceuticals LGND Stock Holding History

Two Sigma Investments’s Portfolio LGND Stock Details LGND Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q2 		– Sell
-2,800
Closed -$294K – 3376
2025
Q1 		$294K Sell
2,800
-207
-7% -$23.4K ﹤0.01% 2724
2024
Q4 		$322K Buy
3,007
+7
+0.2% +$791 ﹤0.01% 2713
2024
Q3 		$300K Hold
3,000
– – ﹤0.01% 2669
2024
Q2 		$253K Buy
+3,000
New +$239K ﹤0.01% 2657
2024
Q1 		– Sell
-3,000
Closed -$214K – 3222
2023
Q4 		$214K Sell
3,000
-3,300
-52% -$195K ﹤0.01% 2813
2023
Q3 		$377K Sell
6,300
-1,000
-14% -$65.8K ﹤0.01% 2399
2023
Q2 		$526K Hold
7,300
– – ﹤0.01% 2306
2023
Q1 		$537K Sell
7,300
-33,465
-82% -$2.38M ﹤0.01% 2174
2022
Q4 		$2.72M Buy
40,765
+34,552
+556% +$2.25M 0.01% 1148
2022
Q3 		$334K Sell
6,213
-25,813
-81% -$1.52M ﹤0.01% 1927
2022
Q2 		$1.78M Buy
+32,026
New +$1.82M 0.01% 1261
2022
Q1 		– Sell
-8,656
Closed -$834K – 3569
2021
Q4 		$834K Hold
8,656
– – ﹤0.01% 2726
2021
Q3 		$752K Hold
8,656
– – ﹤0.01% 2888
2021
Q2 		$708K Sell
8,656
-1,404
-14% -$117K ﹤0.01% 2793
2021
Q1 		$957K Sell
10,060
-44,944
-82% -$4.25M ﹤0.01% 2369
2020
Q4 		$3.41M Sell
55,004
-8,617
-14% -$491K 0.01% 1152
2020
Q3 		$3.78M Sell
63,621
-65,677
-51% -$4.48M 0.01% 935
2020
Q2 		$9.02M Sell
129,298
-32,490
-20% -$2.06M 0.04% 424
2020
Q1 		$7.34M Sell
161,788
-114,417
-41% -$6.49M 0.06% 355
2019
Q4 		$18M Buy
276,205
+113,856
+70% +$7.61M 0.05% 401
2019
Q3 		$10.1M Sell
162,349
-177,267
-52% -$11.1M 0.03% 541
2019
Q2 		$24.2M Sell
339,616
-91,118
-21% -$6.71M 0.08% 318
2019
Q1 		$33.8M Sell
430,734
-15,273
-3% -$1.16M 0.11% 236
2018
Q4 		$37.8M Buy
446,007
+304,619
+215% +$32.5M 0.15% 175
2018
Q3 		$24.2M Sell
141,388
-49,156
-26% -$7.41M 0.07% 373
2018
Q2 		$24.6M Sell
190,544
-48,981
-20% -$5.47M 0.07% 347
2018
Q1 		$24.7M Buy
+239,525
New +$23.7M 0.08% 293
2017
Q4 		– Sell
-94,415
Closed -$8.02M – 3291
2017
Q3 		$8.02M Buy
94,415
+56,357
+148% +$4.46M 0.03% 603
2017
Q2 		$2.88M Buy
+38,058
New +$2.66M 0.01% 1182
2016
Q3 		– Sell
-174,934
Closed -$13M – 3253
2016
Q2 		$13M Buy
174,934
+126,083
+258% +$9.36M 0.06% 400
2016
Q1 		$3.26M Buy
48,851
+16,849
+53% +$1.02M 0.02% 902
2015
Q4 		$2.16M Buy
+32,002
New +$1.98M 0.01% 1051
2015
Q3 		– Sell
-70,732
Closed -$4.45M – 2484
2015
Q2 		$4.45M Sell
70,732
-66,794
-49% -$3.64M 0.02% 772
2015
Q1 		$6.62M Buy
137,526
+60,672
+79% +$2.32M 0.03% 608
2014
Q4 		$2.55M Sell
76,854
-36,640
-32% -$1.19M 0.01% 921
2014
Q3 		$3.33M Buy
113,494
+64,660
+132% +$2.15M 0.01% 729
2014
Q2 		$1.9M Buy
48,834
+11,107
+29% +$451K 0.01% 1043
2014
Q1 		$1.58M Buy
+37,727
New +$1.57M 0.01% 1035
2013
Q4 		– Sell
-71,026
Closed -$1.92M – 2282
2013
Q3 		$1.92M Buy
+71,026
New +$2M 0.01% 794

Other funds holding LGND

BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
Vanguard Group
Vanguard Group Malvern, Pennsylvania $6.9T AUM 27.45% 1-Year Est. Return
Janus Henderson Group
Janus Henderson Group London, United Kingdom $209B AUM 37.72% 1-Year Est. Return
Macquarie Group
Macquarie Group Sydney, NSW 2000, Australia $16.8B AUM 27.39% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
Dimensional Fund Advisors
Dimensional Fund Advisors Austin, Texas $481B AUM 30.42% 1-Year Est. Return
CAM
Congress Asset Management Boston, Massachusetts $16.3B AUM 42.69% 1-Year Est. Return
SIMG
Stephens Investment Management Group Houston, Texas $7.3B AUM 41.96% 1-Year Est. Return
CC
Chicago Capital Chicago, Illinois $4.15B AUM 31.09% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return

Two Sigma Investments's LGND Position: Q2 2025 in Review

Two Sigma Investments sold out of Ligand Pharmaceuticals (LGND) in Q2 2025, closing a stake of 2,800 shares — an estimated $294K sold.

Two Sigma Investments first reported a position in LGND in Q3 2013 and held it in 39 quarters. The position peaked at $37.8M in Q4 2018. 271 funds tracked by Wall St. Rank hold LGND as of Q2 2025.

  • Two Sigma Investments reported no remaining Ligand Pharmaceuticals position as of Q2 2025 after selling out during the quarter.
  • Two Sigma Investments sold 2,800 Ligand Pharmaceuticals shares in Q2 2025, an estimated $294K.
  • Two Sigma Investments first reported a position in Ligand Pharmaceuticals in Q3 2013 and held it in 39 quarters.
  • Two Sigma Investments's Ligand Pharmaceuticals position peaked at $37.8M in Q4 2018.
  • 271 funds tracked by Wall St. Rank held Ligand Pharmaceuticals as of Q2 2025.

Based on Two Sigma Investments's 13F filing for Q2 2025, filed 14 Aug 2025.