Two Sigma Investments
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Two Sigma Investments’s Kiora Pharmaceuticals KPRX Stock Holding History

Two Sigma Investments’s Portfolio KPRX Stock Details KPRX Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q4 		– Sell
-11,984
Closed -$33.3K – 4255
2025
Q3 		$33.3K Buy
+11,984
New +$32.9K ﹤0.01% 3564
2024
Q2 		– Sell
-1,150
Closed -$7.31K – 3189
2024
Q1 		$7.31K Buy
+1,150
New +$6.43K ﹤0.01% 2965
2021
Q3 		– Sell
-75
Closed -$99K – 4488
2021
Q2 		$99K Sell
75
-72
-49% -$112K ﹤0.01% 3899
2021
Q1 		$263K Buy
+147
New +$320K ﹤0.01% 3433

Other funds holding KPRX

ACM
ADAR1 Capital Management Austin, Texas $1.7B AUM 340.85% 1-Year Est. Return
SCM
Stonepine Capital Management Bend, Oregon $250M AUM 77.6% 1-Year Est. Return
DS
DRW Securities Chicago, Illinois $7.21B AUM 20.54% 1-Year Est. Return
NCM
Nantahala Capital Management New Canaan, Connecticut $2.72B AUM 121.58% 1-Year Est. Return
Alyeska Investment Group
Alyeska Investment Group Chicago, Illinois $35.4B AUM 33.54% 1-Year Est. Return
Vanguard Group
Vanguard Group Malvern, Pennsylvania $6.9T AUM 27.45% 1-Year Est. Return
Citadel Advisors
Citadel Advisors Miami, Florida $618B AUM 30.34% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
Renaissance Technologies
Renaissance Technologies New York $63.9B AUM 45.56% 1-Year Est. Return
XT
XTX Topco George Town, Cayman Islands $5.75B AUM 30.56% 1-Year Est. Return

Two Sigma Investments's KPRX Position: Q4 2025 in Review

Two Sigma Investments sold out of Kiora Pharmaceuticals (KPRX) in Q4 2025, closing a stake of 11,984 shares — an estimated $33.3K sold.

Two Sigma Investments first reported a position in KPRX in Q1 2021 and held it in 4 quarters. The position peaked at $263K in Q1 2021. 19 funds tracked by Wall St. Rank hold KPRX as of Q4 2025.

  • Two Sigma Investments reported no remaining Kiora Pharmaceuticals position as of Q4 2025 after selling out during the quarter.
  • Two Sigma Investments sold 11,984 Kiora Pharmaceuticals shares in Q4 2025, an estimated $33.3K.
  • Two Sigma Investments first reported a position in Kiora Pharmaceuticals in Q1 2021 and held it in 4 quarters.
  • Two Sigma Investments's Kiora Pharmaceuticals position peaked at $263K in Q1 2021.
  • 19 funds tracked by Wall St. Rank held Kiora Pharmaceuticals as of Q4 2025.

Based on Two Sigma Investments's 13F filing for Q4 2025, filed 17 Feb 2026.