Two Sigma Investments
IRD

Two Sigma Investments’s Opus Genetics IRD Stock Holding History

Two Sigma Investments’s Portfolio IRD Stock Details IRD Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$1.04M Buy
253,962
+145,321
+134% +$678K ﹤0.01% 3585
2026
Q1 		$494K Sell
108,641
-42,671
-28% -$148K ﹤0.01% 3754
2025
Q4 		$304K Buy
151,312
+42,974
+40% +$87.2K ﹤0.01% 3564
2025
Q3 		$179K Buy
108,338
+68,148
+170% +$84.7K ﹤0.01% 3394
2025
Q2 		$37.9K Buy
+40,190
New +$37.2K ﹤0.01% 3088
2023
Q3 		– Sell
-19,086
Closed -$82.8K – 3264
2023
Q2 		$82.8K Buy
+19,086
New +$90.6K ﹤0.01% 2776
2022
Q2 		– Sell
-51,700
Closed -$168K – 3017
2022
Q1 		$168K Sell
51,700
-68,200
-57% -$233K ﹤0.01% 2363
2021
Q4 		$447K Buy
119,900
+83,017
+225% +$333K ﹤0.01% 3356
2021
Q3 		$190K Buy
+36,883
New +$170K ﹤0.01% 3978
2014
Q3 		– Sell
-39
Closed -$16K – 2103
2014
Q2 		$16K Buy
+39
New +$17.7K ﹤0.01% 2109

Other funds holding IRD

CP
Caligan Partners New York $2.13B AUM 758.65% 1-Year Est. Return
Adage Capital Partners
Adage Capital Partners Boston, Massachusetts $71.3B AUM 56.8% 1-Year Est. Return
BCM
BIOS Capital Management Fort Worth, Texas $41.7M AUM 34.92% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
Balyasny Asset Management
Balyasny Asset Management Chicago, Illinois $80.2B AUM 51.53% 1-Year Est. Return
NCM
Nantahala Capital Management New Canaan, Connecticut $3.01B AUM 119.46% 1-Year Est. Return
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
BCM
Boxer Capital Management San Diego, California $1.33B AUM 864.5% 1-Year Est. Return
TECP
Trails Edge Capital Partners Atlanta, Georgia $630M AUM
Millennium Management
Millennium Management New York $276B AUM 44.8% 1-Year Est. Return

Two Sigma Investments's IRD Position: Q2 2026 in Review

Two Sigma Investments increased its Opus Genetics (IRD) stake by 134% in Q2 2026, buying an estimated $678K and bringing the position to 253,962 shares worth $1.04M. The position accounts for ﹤0.01% of the portfolio, ranked #3585.

Two Sigma Investments first reported a position in IRD in Q2 2014 and has held it in 10 quarters since. 103 funds tracked by Wall St. Rank hold IRD as of Q2 2026.

  • Two Sigma Investments held 253,962 shares of Opus Genetics worth $1.04M as of Q2 2026.
  • Two Sigma Investments bought 145,321 Opus Genetics shares in Q2 2026, an estimated $678K.
  • Opus Genetics made up ﹤0.01% of Two Sigma Investments's portfolio in Q2 2026, its #3585 holding.
  • Two Sigma Investments first reported a position in Opus Genetics in Q2 2014 and has held it in 10 quarters since.
  • 103 funds tracked by Wall St. Rank held Opus Genetics as of Q2 2026.

Based on Two Sigma Investments's 13F filing for Q2 2026, filed 14 Aug 2026.