Two Sigma Investments
INVA icon

Two Sigma Investments’s Innoviva INVA Stock Holding History

Two Sigma Investments’s Portfolio INVA Stock Details INVA Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$34.6M Buy
1,484,264
+644,399
+77% +$13.9M 0.03% 662
2025
Q4 		$16.8M Buy
839,865
+317,623
+61% +$6.2M 0.02% 815
2025
Q3 		$9.53M Buy
522,242
+190,356
+57% +$3.71M 0.01% 984
2025
Q2 		$6.67M Sell
331,886
-335,699
-50% -$6.46M 0.01% 1057
2025
Q1 		$12.1M Buy
667,585
+404,846
+154% +$7.26M 0.03% 695
2024
Q4 		$4.56M Sell
262,739
-221,073
-46% -$4.24M 0.01% 1162
2024
Q3 		$9.34M Sell
483,812
-55,912
-10% -$1.03M 0.02% 791
2024
Q2 		$8.85M Sell
539,724
-9,502
-2% -$147K 0.02% 764
2024
Q1 		$8.37M Buy
549,226
+178,312
+48% +$2.8M 0.02% 724
2023
Q4 		$5.95M Buy
370,914
+82,368
+29% +$1.15M 0.01% 897
2023
Q3 		$3.75M Sell
288,546
-78,782
-21% -$1.02M 0.01% 1047
2023
Q2 		$4.68M Buy
367,328
+349,537
+1,965% +$4.37M 0.01% 949
2023
Q1 		$200K Sell
17,791
-159,595
-90% -$1.94M ﹤0.01% 2555
2022
Q4 		$2.35M Buy
+177,386
New +$2.33M 0.01% 1232
2022
Q3 		– Sell
-414,331
Closed -$6.12M – 2629
2022
Q2 		$6.12M Sell
414,331
-400,072
-49% -$6.55M 0.02% 686
2022
Q1 		$15.8M Buy
814,403
+402,425
+98% +$7.19M 0.05% 453
2021
Q4 		$7.11M Buy
411,978
+110,376
+37% +$1.88M 0.02% 988
2021
Q3 		$5.04M Buy
+301,602
New +$4.51M 0.01% 1220
2020
Q4 		– Sell
-31,273
Closed -$327K – 3530
2020
Q3 		$327K Sell
31,273
-42,428
-58% -$539K ﹤0.01% 2533
2020
Q2 		$1.03M Sell
73,701
-20,102
-21% -$273K 0.01% 1523
2020
Q1 		$1.1M Buy
93,803
+26,403
+39% +$349K 0.01% 1337
2019
Q4 		$954K Buy
+67,400
New +$827K ﹤0.01% 2226
2019
Q2 		– Sell
-14,235
Closed -$200K – 3484
2019
Q1 		$200K Sell
14,235
-286,642
-95% -$4.64M ﹤0.01% 2818
2018
Q4 		$5.25M Buy
+300,877
New +$4.89M 0.02% 771
2018
Q2 		– Sell
-85,000
Closed -$1.42M – 3471
2018
Q1 		$1.42M Buy
85,000
+44,729
+111% +$690K ﹤0.01% 1773
2017
Q4 		$571K Sell
40,271
-77,298
-66% -$1.03M ﹤0.01% 2345
2017
Q3 		$1.66M Buy
+117,569
New +$1.55M 0.01% 1416
2017
Q2 		– Sell
-83,106
Closed -$1.15M – 3111
2017
Q1 		$1.15M Buy
+83,106
New +$978K ﹤0.01% 1834
2016
Q4 		– Sell
-149,455
Closed -$1.64M – 3298
2016
Q3 		$1.64M Buy
149,455
+23,350
+19% +$272K 0.01% 1606
2016
Q2 		$1.33M Buy
126,105
+49,184
+64% +$582K 0.01% 1544
2016
Q1 		$968K Buy
+76,921
New +$844K ﹤0.01% 1621
2013
Q3 		– Sell
-47,713
Closed -$1.48M – 1963
2013
Q2 		$1.48M Buy
+47,713
New +$1.28M 0.01% 995

Other funds holding INVA

BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
Dimensional Fund Advisors
Dimensional Fund Advisors Austin, Texas $481B AUM 30.42% 1-Year Est. Return
VPM
Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM
Renaissance Technologies
Renaissance Technologies New York $63.9B AUM 45.56% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
Millennium Management
Millennium Management New York $240B AUM 35.51% 1-Year Est. Return
SCM
Sarissa Capital Management Greenwich, Connecticut $158M AUM 103.7% 1-Year Est. Return
SFM
Systematic Financial Management Teaneck, New Jersey $4.36B AUM 40.56% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return

Two Sigma Investments's INVA Position: Q1 2026 in Review

Two Sigma Investments increased its Innoviva (INVA) stake by 77% in Q1 2026, buying an estimated $13.9M and bringing the position to 1,484,264 shares worth $34.6M. The position accounts for 0.03% of the portfolio, ranked #662.

Two Sigma Investments first reported a position in INVA in Q2 2013 and has held it in 32 quarters since. 286 funds tracked by Wall St. Rank hold INVA as of Q1 2026.

  • Two Sigma Investments held 1,484,264 shares of Innoviva worth $34.6M as of Q1 2026.
  • Two Sigma Investments bought 644,399 Innoviva shares in Q1 2026, an estimated $13.9M.
  • Innoviva made up 0.03% of Two Sigma Investments's portfolio in Q1 2026, its #662 holding.
  • Two Sigma Investments first reported a position in Innoviva in Q2 2013 and has held it in 32 quarters since.
  • 286 funds tracked by Wall St. Rank held Innoviva as of Q1 2026.

Based on Two Sigma Investments's 13F filing for Q1 2026, filed 15 May 2026.