Two Sigma Investments
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Two Sigma Investments’s Eton Pharmaceutcials ETON Stock Holding History

Two Sigma Investments’s Portfolio ETON Stock Details ETON Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$2.63M Buy
106,393
+29,791
+39% +$521K ﹤0.01% 2558
2025
Q4 		$1.3M Sell
76,602
-209,819
-73% -$3.69M ﹤0.01% 2749
2025
Q3 		$6.22M Buy
286,421
+71,869
+33% +$1.19M 0.01% 1286
2025
Q2 		$3.06M Buy
214,552
+132,197
+161% +$2.09M 0.01% 1547
2025
Q1 		$1.07M Sell
82,355
-30,103
-27% -$455K ﹤0.01% 2134
2024
Q4 		$1.5M Buy
+112,458
New +$1.14M ﹤0.01% 1916
2024
Q3 		– Sell
-16,485
Closed -$54.2K – 3170
2024
Q2 		$54.2K Sell
16,485
-15,305
-48% -$53.6K ﹤0.01% 2880
2024
Q1 		$119K Sell
31,790
-20,710
-39% -$90.4K ﹤0.01% 2813
2023
Q4 		$230K Sell
52,500
-27,052
-34% -$108K ﹤0.01% 2779
2023
Q3 		$332K Buy
+79,552
New +$307K ﹤0.01% 2451
2021
Q4 		– Sell
-18,070
Closed -$91K – 4437
2021
Q3 		$91K Buy
+18,070
New +$94K ﹤0.01% 4093
2021
Q2 		– Sell
-139,989
Closed -$1.02M – 4181
2021
Q1 		$1.02M Buy
139,989
+13,499
+11% +$115K ﹤0.01% 2289
2020
Q4 		$1.03M Buy
+126,490
New +$976K ﹤0.01% 1995

Other funds holding ETON

OM
Opaleye Management Boston, Massachusetts $759M AUM 124.8% 1-Year Est. Return
EC
EcoR1 Capital San Francisco, California $2.36B AUM 204.53% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
NCM
Nantahala Capital Management New Canaan, Connecticut $2.72B AUM 121.58% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
NPT
National Philanthropic Trust Jenkintown, Pennsylvania $9.38B AUM 33.37% 1-Year Est. Return
Morgan Stanley
Morgan Stanley New York $1.66T AUM 25.57% 1-Year Est. Return
WIM
Westside Investment Management Santa Monica, California $761M AUM 39.85% 1-Year Est. Return

Two Sigma Investments's ETON Position: Q1 2026 in Review

Two Sigma Investments increased its Eton Pharmaceutcials (ETON) stake by 39% in Q1 2026, buying an estimated $521K and bringing the position to 106,393 shares worth $2.63M. The position accounts for ﹤0.01% of the portfolio, ranked #2558.

Two Sigma Investments first reported a position in ETON in Q4 2020 and has held it in 13 quarters since. The position peaked at $6.22M in Q3 2025. 116 funds tracked by Wall St. Rank hold ETON as of Q1 2026.

  • Two Sigma Investments held 106,393 shares of Eton Pharmaceutcials worth $2.63M as of Q1 2026.
  • Two Sigma Investments bought 29,791 Eton Pharmaceutcials shares in Q1 2026, an estimated $521K.
  • Eton Pharmaceutcials made up ﹤0.01% of Two Sigma Investments's portfolio in Q1 2026, its #2558 holding.
  • Two Sigma Investments first reported a position in Eton Pharmaceutcials in Q4 2020 and has held it in 13 quarters since.
  • Two Sigma Investments's Eton Pharmaceutcials position peaked at $6.22M in Q3 2025.
  • 116 funds tracked by Wall St. Rank held Eton Pharmaceutcials as of Q1 2026.

Based on Two Sigma Investments's 13F filing for Q1 2026, filed 15 May 2026.