Two Sigma Investments
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Two Sigma Investments’s Black Diamond Therapeutics BDTX Stock Holding History

Two Sigma Investments’s Portfolio BDTX Stock Details BDTX Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$92.2K Buy
+43,300
New +$103K ﹤0.01% 4394
2024
Q4 		– Sell
-84,200
Closed -$366K – 3218
2024
Q3 		$366K Sell
84,200
-99,027
-54% -$539K ﹤0.01% 2597
2024
Q2 		$854K Sell
183,227
-174,837
-49% -$939K ﹤0.01% 2076
2024
Q1 		$1.82M Sell
358,064
-9,229
-3% -$37.2K ﹤0.01% 1554
2023
Q4 		$1.03M Buy
367,293
+287,169
+358% +$674K ﹤0.01% 2052
2023
Q3 		$230K Buy
+80,124
New +$295K ﹤0.01% 2589
2023
Q2 		– Sell
-107,754
Closed -$204K – 3009
2023
Q1 		$204K Sell
107,754
-35,910
-25% -$82.5K ﹤0.01% 2548
2022
Q4 		$259K Sell
143,664
-64,229
-31% -$116K ﹤0.01% 2298
2022
Q3 		$351K Sell
207,893
-52,591
-20% -$162K ﹤0.01% 1912
2022
Q2 		$641K Sell
260,484
-146,939
-36% -$342K ﹤0.01% 1722
2022
Q1 		$1.13M Buy
407,423
+106,421
+35% +$389K ﹤0.01% 1656
2021
Q4 		$1.6M Buy
301,002
+4,196
+1% +$29.3K ﹤0.01% 2122
2021
Q3 		$2.51M Sell
296,806
-117,381
-28% -$1.16M 0.01% 1772
2021
Q2 		$5.05M Buy
414,187
+291,421
+237% +$5.76M 0.01% 1200
2021
Q1 		$2.98M Sell
122,766
-3,374
-3% -$91K 0.01% 1395
2020
Q4 		$4.04M Buy
+126,140
New +$4.14M 0.01% 1053

Other funds holding BDTX

T. Rowe Price Investment Management
T. Rowe Price Investment Management Baltimore, Maryland $145B AUM 22.78% 1-Year Est. Return
NMC
NEA Management Company Timonium, Maryland $1.76B AUM 223.33% 1-Year Est. Return
Acadian Asset Management
Acadian Asset Management Boston, Massachusetts $70.5B AUM 36% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
Renaissance Technologies
Renaissance Technologies New York $63.9B AUM 45.56% 1-Year Est. Return
Dimensional Fund Advisors
Dimensional Fund Advisors Austin, Texas $481B AUM 30.42% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
Connor, Clark & Lunn Investment Management (CC&L)
Connor, Clark & Lunn Investment Management (CC&L) Vancouver, British Columbia, Canada $43.4B AUM 51.29% 1-Year Est. Return
Mackenzie Financial
Mackenzie Financial Toronto Ontario, Ontario, Canada $83.3B AUM 31.19% 1-Year Est. Return
Marshall Wace
Marshall Wace London, United Kingdom $100B AUM 35.1% 1-Year Est. Return

Two Sigma Investments's BDTX Position: Q1 2026 in Review

Two Sigma Investments opened a new position in Black Diamond Therapeutics (BDTX) in Q1 2026: 43,300 shares worth $92.2K. The stake represents ﹤0.01% of the portfolio and ranks #4394 among its holdings. This is a return to the name: Two Sigma Investments previously reported a position in BDTX as recently as Q3 2024.

Two Sigma Investments first reported a position in BDTX in Q4 2020 and has held it in 16 quarters since. The position peaked at $5.05M in Q2 2021. 104 funds tracked by Wall St. Rank hold BDTX as of Q1 2026.

  • Two Sigma Investments held 43,300 shares of Black Diamond Therapeutics worth $92.2K as of Q1 2026.
  • Black Diamond Therapeutics was a new Two Sigma Investments position in Q1 2026.
  • Black Diamond Therapeutics made up ﹤0.01% of Two Sigma Investments's portfolio in Q1 2026, its #4394 holding.
  • Two Sigma Investments first reported a position in Black Diamond Therapeutics in Q4 2020 and has held it in 16 quarters since.
  • Two Sigma Investments's Black Diamond Therapeutics position peaked at $5.05M in Q2 2021.
  • 104 funds tracked by Wall St. Rank held Black Diamond Therapeutics as of Q1 2026.

Based on Two Sigma Investments's 13F filing for Q1 2026, filed 15 May 2026.