Two Sigma Investments
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Two Sigma Investments’s Altimmune ALT Stock Holding History

Two Sigma Investments’s Portfolio ALT Stock Details ALT Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$7.64M Buy
2,478,900
+1,213,217
+96% +$5.15M 0.01% 1629
2025
Q4 		$4.57M Sell
1,265,683
-731,165
-37% -$3.19M 0.01% 1795
2025
Q3 		$7.53M Buy
1,996,848
+1,559,562
+357% +$6.02M 0.01% 1141
2025
Q2 		$1.69M Sell
437,286
-710,530
-62% -$3.85M ﹤0.01% 1942
2025
Q1 		$5.74M Buy
1,147,816
+542,513
+90% +$3.44M 0.01% 1050
2024
Q4 		$4.36M Buy
605,303
+151,001
+33% +$1.15M 0.01% 1188
2024
Q3 		$2.79M Sell
454,302
-122,264
-21% -$828K 0.01% 1463
2024
Q2 		$3.83M Buy
+576,566
New +$4.25M 0.01% 1135
2023
Q4 		– Sell
-667,420
Closed -$1.74M – 3125
2023
Q3 		$1.74M Sell
667,420
-319,400
-32% -$916K ﹤0.01% 1504
2023
Q2 		$3.48M Sell
986,820
-57,367
-5% -$258K 0.01% 1100
2023
Q1 		$4.41M Buy
1,044,187
+267,890
+35% +$3.18M 0.01% 974
2022
Q4 		$12.8M Sell
776,297
-201,350
-21% -$2.26M 0.04% 477
2022
Q3 		$12.5M Buy
977,647
+362,029
+59% +$5.35M 0.04% 428
2022
Q2 		$7.2M Buy
615,618
+11,198
+2% +$69.1K 0.02% 625
2022
Q1 		$3.68M Buy
604,420
+27,998
+5% +$206K 0.01% 1071
2021
Q4 		$5.28M Buy
+576,422
New +$6.12M 0.01% 1168
2021
Q2 		– Sell
-26,399
Closed -$373K – 3993
2021
Q1 		$373K Sell
26,399
-14,453
-35% -$234K ﹤0.01% 3171
2020
Q4 		$461K Sell
40,852
-611,316
-94% -$7.2M ﹤0.01% 2569
2020
Q3 		$8.61M Buy
652,168
+636,269
+4,002% +$12.7M 0.03% 562
2020
Q2 		$170K Buy
+15,899
New +$87.3K ﹤0.01% 2691
2019
Q1 		– Sell
-12,481
Closed -$26K – 2988
2018
Q4 		$26K Buy
+12,481
New +$44.2K ﹤0.01% 2884
2017
Q2 		– Sell
-449
Closed -$109K – 2922
2017
Q1 		$109K Sell
449
-948
-68% -$507K ﹤0.01% 2786
2016
Q4 		$1.36M Buy
+1,397
New +$1.25M 0.01% 1777

Other funds holding ALT

BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
VPM
Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM
Marshall Wace
Marshall Wace London, United Kingdom $100B AUM 35.1% 1-Year Est. Return
Millennium Management
Millennium Management New York $240B AUM 35.51% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
Alyeska Investment Group
Alyeska Investment Group Chicago, Illinois $35.4B AUM 33.54% 1-Year Est. Return
N
Nuveen Charlotte, North Carolina $369B AUM 31.66% 1-Year Est. Return
Goldman Sachs
Goldman Sachs New York $871B AUM 31.28% 1-Year Est. Return

Two Sigma Investments's ALT Position: Q1 2026 in Review

Two Sigma Investments increased its Altimmune (ALT) stake by 96% in Q1 2026, buying an estimated $5.15M and bringing the position to 2,478,900 shares worth $7.64M. The position accounts for 0.01% of the portfolio, ranked #1629.

Two Sigma Investments first reported a position in ALT in Q4 2016 and has held it in 23 quarters since. The position peaked at $12.8M in Q4 2022. 173 funds tracked by Wall St. Rank hold ALT as of Q1 2026.

  • Two Sigma Investments held 2,478,900 shares of Altimmune worth $7.64M as of Q1 2026.
  • Two Sigma Investments bought 1,213,217 Altimmune shares in Q1 2026, an estimated $5.15M.
  • Altimmune made up 0.01% of Two Sigma Investments's portfolio in Q1 2026, its #1629 holding.
  • Two Sigma Investments first reported a position in Altimmune in Q4 2016 and has held it in 23 quarters since.
  • Two Sigma Investments's Altimmune position peaked at $12.8M in Q4 2022.
  • 173 funds tracked by Wall St. Rank held Altimmune as of Q1 2026.

Based on Two Sigma Investments's 13F filing for Q1 2026, filed 15 May 2026.