Two Sigma Investments
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Two Sigma Investments’s Acumen Pharmaceuticals ABOS Stock Holding History

Two Sigma Investments’s Portfolio ABOS Stock Details ABOS Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$1.25M Buy
530,812
+387,591
+271% +$989K ﹤0.01% 3088
2025
Q4 		$302K Sell
143,221
-56,225
-28% -$112K ﹤0.01% 3567
2025
Q3 		$341K Sell
199,446
-1,339
-0.7% -$1.85K ﹤0.01% 3161
2025
Q2 		$233K Sell
200,785
-31,508
-14% -$33.9K ﹤0.01% 2871
2025
Q1 		$256K Sell
232,293
-68,975
-23% -$98.5K ﹤0.01% 2777
2024
Q4 		$518K Sell
301,268
-8,239
-3% -$19.8K ﹤0.01% 2524
2024
Q3 		$768K Sell
309,507
-1,290
-0.4% -$3.5K ﹤0.01% 2263
2024
Q2 		$752K Buy
310,797
+132,896
+75% +$423K ﹤0.01% 2148
2024
Q1 		$720K Sell
177,901
-66,515
-27% -$251K ﹤0.01% 2150
2023
Q4 		$939K Buy
244,416
+112,065
+85% +$333K ﹤0.01% 2119
2023
Q3 		$549K Buy
132,351
+105,716
+397% +$653K ﹤0.01% 2236
2023
Q2 		$128K Sell
26,635
-27,447
-51% -$131K ﹤0.01% 2724
2023
Q1 		$220K Sell
54,082
-33,794
-38% -$176K ﹤0.01% 2527
2022
Q4 		$475K Buy
+87,876
New +$590K ﹤0.01% 2045
2022
Q3 		– Sell
-15,311
Closed -$72K – 2434
2022
Q2 		$72K Buy
+15,311
New +$57.5K ﹤0.01% 2311

Other funds holding ABOS

RCM
RA Capital Management Boston, Massachusetts $9.44B AUM 157.3% 1-Year Est. Return
SCV
Sands Capital Ventures Arlington, Virginia $421M AUM 26.25% 1-Year Est. Return
Alyeska Investment Group
Alyeska Investment Group Chicago, Illinois $35.4B AUM 33.54% 1-Year Est. Return
Franklin Resources
Franklin Resources San Mateo, California $408B AUM 30.18% 1-Year Est. Return
ACM
ADAR1 Capital Management Austin, Texas $1.7B AUM 340.85% 1-Year Est. Return
KIA
Knollwood Investment Advisory Hunt Valley, Maryland $992M AUM 28.95% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
IC
Ikarian Capital Dallas, Texas $1.23B AUM 600.17% 1-Year Est. Return
Hudson Bay Capital Management
Hudson Bay Capital Management Stamford, Connecticut $29B AUM 30.2% 1-Year Est. Return

Two Sigma Investments's ABOS Position: Q1 2026 in Review

Two Sigma Investments increased its Acumen Pharmaceuticals (ABOS) stake by 271% in Q1 2026, buying an estimated $989K and bringing the position to 530,812 shares worth $1.25M. The position accounts for ﹤0.01% of the portfolio, ranked #3088.

Two Sigma Investments first reported a position in ABOS in Q2 2022 and has held it in 15 quarters since. 84 funds tracked by Wall St. Rank hold ABOS as of Q1 2026.

  • Two Sigma Investments held 530,812 shares of Acumen Pharmaceuticals worth $1.25M as of Q1 2026.
  • Two Sigma Investments bought 387,591 Acumen Pharmaceuticals shares in Q1 2026, an estimated $989K.
  • Acumen Pharmaceuticals made up ﹤0.01% of Two Sigma Investments's portfolio in Q1 2026, its #3088 holding.
  • Two Sigma Investments first reported a position in Acumen Pharmaceuticals in Q2 2022 and has held it in 15 quarters since.
  • 84 funds tracked by Wall St. Rank held Acumen Pharmaceuticals as of Q1 2026.

Based on Two Sigma Investments's 13F filing for Q1 2026, filed 15 May 2026.