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Two Sigma Advisers

Two Sigma Advisers Portfolio holdings

AUM $51.4B
1-Year Est. Return 31.07%
This Fund
S&P 500
This Quarter Est. Return
-3%
1 Year Est. Return
+31.07%
3 Year Est. Return
+128.94%
5 Year Est. Return
+161.75%
10 Year Est. Return
+607.04%
AUM
$44.4B
AUM Growth
+$1.2B
Cap. Flow
+$3.32B
Cap. Flow %
7.48%
Top 10 Hldgs %
17.65%
Holding
2,641
New
312
Increased
1,037
Reduced
994
Closed
281

Top Buys

Rank Stock Value
1
AVGO icon
Broadcom
AVGO
+$519M
2
CRM icon
Salesforce
CRM
+$460M
3
REGN icon
Regeneron Pharmaceuticals
REGN
+$381M
4
BSX icon
Boston Scientific
BSX
+$347M
5
ISRG icon
Intuitive Surgical
ISRG
+$319M

Top Sells

Rank Stock Value
1
V icon
Visa
V
+$555M
2
LLY icon
Eli Lilly
LLY
+$536M
3
META icon
Meta Platforms (Facebook)
META
+$433M
4
PGR icon
Progressive
PGR
+$330M
5
LRCX icon
Lam Research
LRCX
+$294M

Sector Composition

Rank Sector Weight
1 Technology 25.86%
2 Healthcare 15.38%
3 Financials 14.3%
4 Consumer Discretionary 11.43%
5 Industrials 10.56%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
AMKR icon
2376
Amkor Technology
AMKR
$11.3B
– –
-16,000
Closed -$411K
AMT icon
2377
American Tower
AMT
$79.9B
– –
-16,300
Closed -$2.99M
ANNX icon
2378
Annexon
ANNX
$814M
– –
-17,400
Closed -$89.3K
AON icon
2379
Aon
AON
$81.4B
– –
-65,300
Closed -$23.5M
ARE icon
2380
Alexandria Real Estate Equities
ARE
$9.41B
– –
-138,300
Closed -$13.5M
ARIS
2381
DELISTED
Aris Water Solutions
ARIS
– –
-9,200
Closed -$220K
ASB icon
2382
Associated Banc-Corp
ASB
$5.86B
– –
-11,800
Closed -$282K
ASM
2383
Avino Silver & Gold Mines
ASM
$964M
– –
-75,600
Closed -$66.6K
ASND icon
2384
Ascendis Pharma A/S
ASND
$16.7B
– –
-5,400
Closed -$743K
ASPI icon
2385
ASP Isotopes
ASPI
$475M
– –
-88,700
Closed -$402K
ASTL icon
2386
Algoma Steel
ASTL
$463M
– –
-12,000
Closed -$117K
ATAI icon
2387
AtaiBeckley Inc
ATAI
$2.66B
– –
-26,700
Closed -$35.5K
ATLC icon
2388
Atlanticus Holdings
ATLC
$1.58B
– –
-3,600
Closed -$201K
AVO icon
2389
Mission Produce
AVO
$1.13B
– –
-24,400
Closed -$351K
AWR icon
2390
American States Water
AWR
$3.45B
– –
-7,700
Closed -$598K
AZN icon
2391
AstraZeneca
AZN
$267B
– –
-43,050
Closed -$5.64M
AZUL
2392
DELISTED
Azul
AZUL
– –
-22,400
Closed -$37.4K
BALY icon
2393
Bally's
BALY
$720M
– –
-14,000
Closed -$250K
BJ icon
2394
BJs Wholesale Club
BJ
$12.4B
– –
-58,000
Closed -$5.18M
BLD
2395
DELISTED
TopBuild
BLD
– –
-14,500
Closed -$4.51M
BLKB icon
2396
Blackbaud
BLKB
$1.65B
– –
-3,400
Closed -$251K
BRO icon
2397
Brown & Brown
BRO
$24.6B
– –
-41,700
Closed -$4.25M
BUD icon
2398
AB InBev
BUD
$161B
– –
-343,102
Closed -$17.2M
BW icon
2399
Babcock & Wilcox
BW
$1.31B
– –
-26,734
Closed -$43.8K
BWMN icon
2400
Bowman Consulting
BWMN
$463M
– –
-16,800
Closed -$419K
94 95
96
97 98

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Two Sigma Advisers's Q1 2025 Portfolio in Review

As of Q1 2025, Two Sigma Advisers held 2,641 positions worth $44.4B, up 2.8% from $43.2B the previous quarter. Its ten largest holdings account for 18% of the portfolio.

Two Sigma Advisers deployed $3.32B of net new capital in Q1 2025, opening 312 new positions and adding to 1,037 existing holdings. Its largest new stake was Regeneron Pharmaceuticals: 553,800 shares worth $351M.

By sector, the portfolio is most concentrated in Technology at 26% of assets, up from 25% a quarter earlier, followed by Healthcare and Financials.

On the sell side, the largest reduction was Visa, an estimated $555M trimmed.

  • Two Sigma Advisers's largest Q1 2025 buy was Regeneron Pharmaceuticals: 553,800 shares worth $351M.
  • Two Sigma Advisers added most to Broadcom in Q1 2025, an estimated $519M increase.
  • Two Sigma Advisers's biggest Q1 2025 reduction was Visa, cutting an estimated $555M.
  • Two Sigma Advisers fully exited Abbott in Q1 2025, selling an estimated $158M.
  • Two Sigma Advisers's ten largest holdings make up 18% of its $44.4B portfolio in Q1 2025.
  • Two Sigma Advisers opened 312 new positions and closed 281 in Q1 2025.
  • Two Sigma Advisers's portfolio value rose 2.8% quarter-over-quarter to $44.4B.

Based on Two Sigma Advisers's 13F filing for Q1 2025, filed 15 May 2025.