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Two Sigma Advisers

Two Sigma Advisers Portfolio holdings

AUM $51.4B
1-Year Est. Return 31.07%
This Fund
S&P 500
This Quarter Est. Return
-3%
1 Year Est. Return
+31.07%
3 Year Est. Return
+128.94%
5 Year Est. Return
+161.75%
10 Year Est. Return
+607.04%
AUM
$44.4B
AUM Growth
+$1.2B
Cap. Flow
+$3.32B
Cap. Flow %
7.48%
Top 10 Hldgs %
17.65%
Holding
2,641
New
312
Increased
1,037
Reduced
994
Closed
281

Top Buys

Rank Stock Value
1
AVGO icon
Broadcom
AVGO
+$519M
2
CRM icon
Salesforce
CRM
+$460M
3
REGN icon
Regeneron Pharmaceuticals
REGN
+$381M
4
BSX icon
Boston Scientific
BSX
+$347M
5
ISRG icon
Intuitive Surgical
ISRG
+$319M

Top Sells

Rank Stock Value
1
V icon
Visa
V
+$555M
2
LLY icon
Eli Lilly
LLY
+$536M
3
META icon
Meta Platforms (Facebook)
META
+$433M
4
PGR icon
Progressive
PGR
+$330M
5
LRCX icon
Lam Research
LRCX
+$294M

Sector Composition

Rank Sector Weight
1 Technology 25.86%
2 Healthcare 15.38%
3 Financials 14.3%
4 Consumer Discretionary 11.43%
5 Industrials 10.56%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
PLCE icon
2176
Children's Place
PLCE
$55.1M
$160K ﹤0.01%
18,300
-22,600
-55% -$210K
PTLO icon
2177
Portillo's
PTLO
$345M
$157K ﹤0.01%
13,200
-3,000
-19% -$39K
STRO icon
2178
Sutro Biopharma
STRO
$389M
$157K ﹤0.01%
24,090
-30,690
-56% -$483K
FIRY
2179
Firy Inc
FIRY
$153M
$157K ﹤0.01%
34,810
+7,200
+26% +$41.1K
KYTX icon
2180
Kyverna Therapeutics
KYTX
$438M
$156K ﹤0.01%
80,900
+610
+0.8% +$1.8K
CGEN icon
2181
Compugen
CGEN
$213M
$155K ﹤0.01%
106,184
+70,400
+197% +$137K
ARVN icon
2182
Arvinas
ARVN
$530M
$154K ﹤0.01%
21,900
-260,700
-92% -$4.09M
WOW
2183
DELISTED
WideOpenWest
WOW
$153K ﹤0.01%
31,000
-21,300
-41% -$97.9K
VIRC icon
2184
Virco
VIRC
$93.9M
$153K ﹤0.01%
16,200
+2,700
+20% +$28.1K
LUNR icon
2185
Intuitive Machines
LUNR
$1.87B
$153K ﹤0.01%
20,511
-253,205
-93% -$3.98M
RMNI icon
2186
Rimini Street
RMNI
$464M
$152K ﹤0.01%
43,800
-19,700
-31% -$63.8K
NRDS icon
2187
NerdWallet
NRDS
$637M
$151K ﹤0.01%
16,700
+600
+4% +$7.19K
TLRY icon
2188
Tilray
TLRY
$481M
$150K ﹤0.01%
22,860
+6,380
+39% +$59K
ARLO icon
2189
Arlo Technologies
ARLO
$1.59B
$150K ﹤0.01%
15,226
+400
+3% +$4.57K
FNA
2190
DELISTED
Paragon 28, Inc.
FNA
$150K ﹤0.01%
+11,500
New +$143K
HLVX
2191
DELISTED
HilleVax
HLVX
$148K ﹤0.01%
102,376
+61,176
+148% +$113K
MTA
2192
Metalla Royalty & Streaming
MTA
$691M
$146K ﹤0.01%
51,100
+23,800
+87% +$68.8K
PK icon
2193
Park Hotels & Resorts
PK
$3.09B
$144K ﹤0.01%
13,500
-14,500
-52% -$184K
BRBS icon
2194
Blue Ridge Bankshares
BRBS
$313M
$143K ﹤0.01%
44,000
+28,300
+180% +$96.7K
ASLE icon
2195
AerSale
ASLE
$295M
$142K ﹤0.01%
+19,000
New +$136K
RPC
2196
Ridgepost Capital
RPC
$931M
$142K ﹤0.01%
12,100
-14,000
-54% -$178K
PERI icon
2197
Perion Network
PERI
$381M
$142K ﹤0.01%
17,400
-99,200
-85% -$866K
CCLD icon
2198
CareCloud
CCLD
$103M
$141K ﹤0.01%
101,200
+79,000
+356% +$233K
ANVS icon
2199
Annovis Bio
ANVS
$73.6M
$139K ﹤0.01%
+92,921
New +$284K
CLYM
2200
Climb Bio
CLYM
$703M
$139K ﹤0.01%
114,000
+2,300
+2% +$3.73K
86 87
88
89 90

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Two Sigma Advisers's Q1 2025 Portfolio in Review

As of Q1 2025, Two Sigma Advisers held 2,641 positions worth $44.4B, up 2.8% from $43.2B the previous quarter. Its ten largest holdings account for 18% of the portfolio.

Two Sigma Advisers deployed $3.32B of net new capital in Q1 2025, opening 312 new positions and adding to 1,037 existing holdings. Its largest new stake was Regeneron Pharmaceuticals: 553,800 shares worth $351M.

By sector, the portfolio is most concentrated in Technology at 26% of assets, up from 25% a quarter earlier, followed by Healthcare and Financials.

On the sell side, the largest reduction was Visa, an estimated $555M trimmed.

  • Two Sigma Advisers's largest Q1 2025 buy was Regeneron Pharmaceuticals: 553,800 shares worth $351M.
  • Two Sigma Advisers added most to Broadcom in Q1 2025, an estimated $519M increase.
  • Two Sigma Advisers's biggest Q1 2025 reduction was Visa, cutting an estimated $555M.
  • Two Sigma Advisers fully exited Abbott in Q1 2025, selling an estimated $158M.
  • Two Sigma Advisers's ten largest holdings make up 18% of its $44.4B portfolio in Q1 2025.
  • Two Sigma Advisers opened 312 new positions and closed 281 in Q1 2025.
  • Two Sigma Advisers's portfolio value rose 2.8% quarter-over-quarter to $44.4B.

Based on Two Sigma Advisers's 13F filing for Q1 2025, filed 15 May 2025.