Two Sigma Advisers
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Two Sigma Advisers’s Xeris Biopharma Holdings XERS Stock Holding History

Two Sigma Advisers’s Portfolio XERS Stock Details XERS Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		– Sell
-849,334
Closed -$6.67M – 2187
2025
Q4 		$6.67M Sell
849,334
-43,908
-5% -$346K 0.01% 693
2025
Q3 		$7.27M Sell
893,242
-163,537
-15% -$1.09M 0.01% 605
2025
Q2 		$4.94M Buy
1,056,779
+131,164
+14% +$601K 0.01% 748
2025
Q1 		$5.08M Buy
925,615
+911,874
+6,636% +$3.68M 0.01% 786
2024
Q4 		$46.6K Buy
+13,741
New +$44.2K ﹤0.01% 2288
2024
Q3 		– Sell
-23,559
Closed -$53K – 2554
2024
Q2 		$53K Buy
23,559
+13,462
+133% +$27.1K ﹤0.01% 2359
2024
Q1 		$22.3K Buy
+10,097
New +$26.1K ﹤0.01% 2394
2022
Q4 		– Sell
-22,100
Closed -$34K – 2718
2022
Q3 		$34K Sell
22,100
-43,700
-66% -$72.3K ﹤0.01% 2406
2022
Q2 		$101K Buy
65,800
+52,900
+410% +$112K ﹤0.01% 2391
2022
Q1 		$33K Buy
+12,900
New +$31.5K ﹤0.01% 2632
2021
Q3 		– Sell
-71,900
Closed -$293K – 2705
2021
Q2 		$293K Buy
71,900
+51,200
+247% +$195K ﹤0.01% 2151
2021
Q1 		$93K Buy
+20,700
New +$112K ﹤0.01% 2454
2020
Q4 		– Sell
-19,900
Closed -$118K – 2622
2020
Q3 		$118K Sell
19,900
-38,400
-66% -$154K ﹤0.01% 2251
2020
Q2 		$155K Buy
58,300
+25,800
+79% +$89.8K ﹤0.01% 2300
2020
Q1 		$63K Buy
+32,500
New +$140K ﹤0.01% 2360

Other funds holding XERS

BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
D.E. Shaw & Co
D.E. Shaw & Co New York $166B AUM 43.98% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
Qube Research & Technologies (QRT)
Qube Research & Technologies (QRT) London, United Kingdom $89.9B AUM 20.22% 1-Year Est. Return
RA
Rosalind Advisors Toronto, Ontario, Canada $249M AUM 80.12% 1-Year Est. Return
N
Nuveen Charlotte, North Carolina $369B AUM 31.66% 1-Year Est. Return
VPM
Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM
Morgan Stanley
Morgan Stanley New York $1.66T AUM 25.57% 1-Year Est. Return

Two Sigma Advisers's XERS Position: Q1 2026 in Review

Two Sigma Advisers sold out of Xeris Biopharma Holdings (XERS) in Q1 2026, closing a stake of 849,334 shares — an estimated $6.67M sold.

Two Sigma Advisers first reported a position in XERS in Q1 2020 and held it in 15 quarters. The position peaked at $7.27M in Q3 2025. 237 funds tracked by Wall St. Rank hold XERS as of Q1 2026.

  • Two Sigma Advisers reported no remaining Xeris Biopharma Holdings position as of Q1 2026 after selling out during the quarter.
  • Two Sigma Advisers sold 849,334 Xeris Biopharma Holdings shares in Q1 2026, an estimated $6.67M.
  • Two Sigma Advisers first reported a position in Xeris Biopharma Holdings in Q1 2020 and held it in 15 quarters.
  • Two Sigma Advisers's Xeris Biopharma Holdings position peaked at $7.27M in Q3 2025.
  • 237 funds tracked by Wall St. Rank held Xeris Biopharma Holdings as of Q1 2026.

Based on Two Sigma Advisers's 13F filing for Q1 2026.