Tocqueville Asset Management’s Spark Therapeutics, Inc. Common Stock ONCE Stock Holding History

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2019 Q1	–	Sell	-20,925	Closed	-$819K	–	809
2018 Q4	$819K	Sell	20,925 -4,100	-16%	-$178K	0.01%	486
2018 Q3	$1.36M	Sell	25,025 -16,200	-39%	-$1.11M	0.02%	458
2018 Q2	$3.41M	Buy	41,225 +1,075	+3%	+$83K	0.04%	367
2018 Q1	$2.67M	Sell	40,150 -2,000	-5%	-$115K	0.03%	399
2017 Q4	$2.17M	Sell	42,150 -1,700	-4%	-$122K	0.02%	430
2017 Q3	$3.91M	Sell	43,850 -1,500	-3%	-$114K	0.05%	359
2017 Q2	$2.71M	Sell	45,350 -14,500	-24%	-$810K	0.03%	385
2017 Q1	$3.19M	Buy	59,850 +5,500	+10%	+$327K	0.04%	360
2016 Q4	$2.71M	Buy	54,350 +7,200	+15%	+$386K	0.03%	369
2016 Q3	$2.83M	Sell	47,150 -3,500	-7%	-$202K	0.03%	366
2016 Q2	$2.59M	Buy	50,650 +2,000	+4%	+$85.5K	0.03%	374
2016 Q1	$1.44M	Buy	48,650 +4,325	+10%	+$136K	0.02%	442
2015 Q4	$2.01M	Buy	44,325 +6,100	+16%	+$320K	0.03%	422
2015 Q3	$1.59M	Buy	38,225 +34,225	+856%	+$1.79M	0.02%	479
2015 Q2	$241K	Buy	+4,000	New	+$264K	﹤0.01%	890