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TCG Crossover Management

TCG Crossover Management Portfolio holdings

AUM $4.16B Turnover 31.15%
1-Year Est. Return 983.43%
This Fund
S&P 500
This Quarter Est. Return
+83.13%
1 Year Est. Return
+983.43%
3 Year Est. Return
+3,012.95%
5 Year Est. Return
–
10 Year Est. Return
–
AUM
$567M
AUM Growth
+$233M
Cap. Flow
+$110M
Cap. Flow %
19.49%
Top 10 Hldgs %
79.55%
Holding
26
New
5
Increased
7
Reduced
4
Closed
5
Avg Time Held
0.6 years
Top 10 Avg Time Held
0.6 years
Top 20 Avg Time Held
0.6 years
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow Held Since
ISEE
1
DELISTED
IVERIC bio, Inc. Common Stock
ISEE
$110M 19.43%
5,141,118
+1,263,215
+33% +$27M
2021 Q4
4 quarters
MDGL icon
2
Madrigal Pharmaceuticals
MDGL
$10.6B
$83.6M 14.76%
288,054
+258,054
+860% +$25.2M
2022 Q3
1 quarter
COGT icon
3
Cogent Biosciences
COGT
$4.88B
$42M 7.41%
3,631,042
+150,000
+4% +$1.86M
2021 Q4
4 quarters
CBAY icon
4
DELISTED
Cymabay Therapeutics
CBAY
$37M 6.53%
5,905,400
– –
2021 Q4
4 quarters
GERN icon
5
Geron
GERN
$765M
$36.8M 6.49%
15,187,073
+3,071,147
+25% +$6.88M
2022 Q1
3 quarters
SLN icon
6
Silence Therapeutics
SLN
$558M
$32.1M 5.67%
2,104,875
– –
2022 Q3
1 quarter
JBIO icon
7
Jade Biosciences
JBIO
$855M
$31.7M 5.59%
30,894
+3,478
+13% +$2.53M
2021 Q4
4 quarters
VRDN icon
8
Viridian Therapeutics
VRDN
$2.08B
$28.7M 5.07%
983,610
-180,390
-15% -$4.16M
2021 Q4
4 quarters
VTYX icon
9
DELISTED
Ventyx Biosciences
VTYX
$25.8M 4.56%
+787,231
New +$23.3M
2022 Q4
0 quarters
KALV icon
10
DELISTED
KalVista Pharmaceuticals
KALV
$23M 4.05%
+3,395,495
New +$18.2M
2022 Q4
0 quarters
VECT
11
DELISTED
VectivBio Holding AG Ordinary Shares
VECT
$20.2M 3.57%
+2,333,300
New +$18.8M
2022 Q4
0 quarters
ACRS icon
12
Aclaris Therapeutics
ACRS
$498M
$18M 3.18%
1,144,939
– –
2021 Q4
4 quarters
KURA icon
13
Kura Oncology
KURA
$855M
$17.7M 3.12%
1,423,642
+75,000
+6% +$1.09M
2022 Q1
3 quarters
IMVT icon
14
Immunovant
IMVT
$5.76B
$15.2M 2.68%
+854,853
New +$10.8M
2022 Q4
0 quarters
TYRA icon
15
Tyra Biosciences
TYRA
$1.29B
$15.1M 2.67%
1,989,103
+1,043,396
+110% +$7.38M
2021 Q4
4 quarters
MLTX icon
16
MoonLake Immunotherapeutics
MLTX
$863M
$10.5M 1.85%
1,000,000
– –
2022 Q2
2 quarters
TRDA icon
17
Entrada Therapeutics
TRDA
$177M
$7.91M 1.4%
584,955
-57,234
-9% -$1M
2021 Q4
4 quarters
MRUS icon
18
DELISTED
Merus
MRUS
$4.64M 0.82%
300,000
– –
2021 Q4
4 quarters
CABA icon
19
Cabaletta Bio
CABA
$275M
$4.5M 0.79%
+486,795
New +$1.77M
2022 Q4
0 quarters
ALPN icon
20
DELISTED
Alpine Immune Sciences Inc
ALPN
$1.86M 0.33%
253,069
-1,500
-0.6% -$9.59K
2021 Q4
4 quarters
ELEV icon
21
DELISTED
Elevation Oncology
ELEV
$274K 0.05%
288,390
-266,610
-48% -$271K
2021 Q4
4 quarters
ALLK icon
22
DELISTED
Allakos
ALLK
– –
-1,643,500
Closed -$10.1M –
DNTH icon
23
Dianthus Therapeutics
DNTH
$4.18B
– –
-132,758
Closed -$3M –
TNGX icon
24
Tango Therapeutics
TNGX
$3.74B
– –
-1,172,250
Closed -$4.24M –
ZLAB icon
25
Zai Lab
ZLAB
$2.53B
– –
-72,777
Closed -$2.49M –

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TCG Crossover Management's Q4 2022 Portfolio in Review

As of Q4 2022, TCG Crossover Management held 26 positions worth $567M, up 70% from $333M the previous quarter. Its ten largest holdings account for 80% of the portfolio.

TCG Crossover Management deployed $110M of net new capital in Q4 2022, opening 5 new positions and adding to 7 existing holdings. Its largest new stake was Ventyx Biosciences: 787,231 shares worth $25.8M.

By sector, the portfolio is most concentrated in Healthcare at 100% of assets, unchanged from a quarter earlier.

On the sell side, the largest reduction was Viridian Therapeutics, an estimated $4.16M trimmed.

  • TCG Crossover Management's largest Q4 2022 buy was Ventyx Biosciences: 787,231 shares worth $25.8M.
  • TCG Crossover Management added most to IVERIC bio, Inc. Common Stock in Q4 2022, an estimated $27M increase.
  • TCG Crossover Management's biggest Q4 2022 reduction was Viridian Therapeutics, cutting an estimated $4.16M.
  • TCG Crossover Management fully exited Allakos in Q4 2022, selling an estimated $10.1M.
  • TCG Crossover Management's ten largest holdings make up 80% of its $567M portfolio in Q4 2022.
  • TCG Crossover Management opened 5 new positions and closed 5 in Q4 2022.
  • TCG Crossover Management's portfolio value rose 70% quarter-over-quarter to $567M.

Based on TCG Crossover Management's 13F filing for Q4 2022, filed 14 Feb 2023.