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TCG Crossover Management Portfolio holdings

AUM $4.16B
1-Year Est. Return 983.43%
This Fund
S&P 500
This Quarter Est. Return
+25.95%
1 Year Est. Return
+983.43%
3 Year Est. Return
+3,012.95%
5 Year Est. Return
–
10 Year Est. Return
–
AUM
$4.16B
AUM Growth
+$665M
Cap. Flow
-$4.87M
Cap. Flow %
-0.12%
Top 10 Hldgs %
57.45%
Holding
61
New
12
Increased
2
Reduced
9
Closed
7

Top Buys

Rank Stock Value
1
ZLAB icon
Zai Lab
ZLAB
+$121M
2
AURA icon
Aura Biosciences
AURA
+$68.2M
3
TRAX
First Tracks Biotherapeutics
TRAX
+$54.1M
4
AVTX icon
Avalo Therapeutics
AVTX
+$36M
5
EDIT icon
Editas Medicine
EDIT
+$32.5M

Top Sells

Rank Stock Value
1
CNTA
Centessa Pharmaceuticals
CNTA
+$170M
2
ABVX
Abivax
ABVX
+$53.6M
3
FULC icon
Fulcrum Therapeutics
FULC
+$40.3M
4
TNGX icon
Tango Therapeutics
TNGX
+$35.8M
5
RVMD icon
Revolution Medicines
RVMD
+$34.4M

Sector Composition

Rank Sector Weight
1 Healthcare 99.82%
2 Financials 0.18%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
LONA
51
LeonaBio Inc
LONA
$74.8M
$4.27M 0.1%
464,398
– –
JATT
52
JATT II Acquisition Corp
JATT
$93.6M
$2.27M 0.05%
+200,000
New +$2.13M
CNTX icon
53
Context Therapeutics
CNTX
$35.3M
$1.49M 0.04%
2,682,696
– –
EIKN
54
Eikon Therapeutics
EIKN
$595M
$495K 0.01%
+37,902
New +$387K
CNTA
55
DELISTED
Centessa Pharmaceuticals
CNTA
– –
-4,286,480
Closed -$170M
FULC icon
56
Fulcrum Therapeutics
FULC
$294M
– –
-5,250,000
Closed -$40.3M
GPCR icon
57
Structure Therapeutics
GPCR
$3.38B
– –
-140,411
Closed -$6.77M
LQDA icon
58
Liquidia Corp
LQDA
$6.06B
– –
-403,048
Closed -$15.2M
URGN icon
59
UroGen Pharma
URGN
$2.13B
– –
-405,365
Closed -$7.29M
VTGN icon
60
VistaGen Therapeutics
VTGN
$11.2M
– –
-2,676,580
Closed -$1.53M
UPB
61
Upstream Bio Inc
UPB
$366M
– –
-181,063
Closed -$1.63M
1 2
3

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TCG Crossover Management's Q2 2026 Portfolio in Review

As of Q2 2026, TCG Crossover Management held 61 positions worth $4.16B, up 19% from $3.5B the previous quarter. Its ten largest holdings account for 57% of the portfolio.

TCG Crossover Management's Q2 2026 filing shows 12 new, 2 increased, 9 reduced and 7 closed positions. Its largest new stake was Zai Lab: 6,137,627 shares worth $117M. The largest sale was Centessa Pharmaceuticals, an estimated $170M.

By sector, the portfolio is most concentrated in Healthcare at 100% of assets, down from 100% a quarter earlier, followed by Financials.

  • TCG Crossover Management's largest Q2 2026 buy was Zai Lab: 6,137,627 shares worth $117M.
  • TCG Crossover Management added most to Avalo Therapeutics in Q2 2026, an estimated $36M increase.
  • TCG Crossover Management's biggest Q2 2026 reduction was Abivax, cutting an estimated $53.6M.
  • TCG Crossover Management fully exited Centessa Pharmaceuticals in Q2 2026, selling an estimated $170M.
  • TCG Crossover Management's ten largest holdings make up 57% of its $4.16B portfolio in Q2 2026.
  • TCG Crossover Management opened 12 new positions and closed 7 in Q2 2026.
  • TCG Crossover Management's portfolio value rose 19% quarter-over-quarter to $4.16B.

Based on TCG Crossover Management's 13F filing for Q2 2026, filed 14 Aug 2026.