Squarepoint
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Squarepoint’s Karyopharm Therapeutics KPTI Stock Holding History

Squarepoint’s Portfolio KPTI Stock Details KPTI Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q3 		– Sell
-63,801
Closed -$623K – 4765
2026
Q2 		$623K Buy
+63,801
New +$553K ﹤0.01% 3252
2025
Q1 		– Sell
-1,386
Closed -$14.1K – 5038
2024
Q4 		$14.1K Buy
+1,386
New +$16.8K ﹤0.01% 4951
2023
Q4 		– Sell
-2,277
Closed -$45.8K – 4260
2023
Q3 		$45.8K Buy
+2,277
New +$51.1K ﹤0.01% 3645
2023
Q2 		– Sell
-837
Closed -$48.8K – 3800
2023
Q1 		$48.8K Sell
837
-2,649
-76% -$131K ﹤0.01% 3065
2022
Q4 		$178K Buy
+3,486
New +$242K ﹤0.01% 2826
2022
Q1 		– Sell
-8,285
Closed -$799K – 3204
2021
Q4 		$799K Buy
+8,285
New +$826K ﹤0.01% 1839
2021
Q3 		– Sell
-2,294
Closed -$355K – 3183
2021
Q2 		$355K Buy
+2,294
New +$333K ﹤0.01% 2402
2021
Q1 		– Sell
-5,337
Closed -$1.24M – 3370
2020
Q4 		$1.24M Sell
5,337
-5,231
-49% -$1.21M 0.01% 1188
2020
Q3 		$2.31M Buy
10,568
+7,811
+283% +$1.91M 0.03% 595
2020
Q2 		$783K Sell
2,757
-1,059
-28% -$313K 0.01% 1075
2020
Q1 		$1.1M Buy
3,816
+2,257
+145% +$623K 0.03% 685
2019
Q4 		$448K Buy
+1,559
New +$338K ﹤0.01% 1833
2019
Q3 		– Sell
-1,304
Closed -$117K – 2521
2019
Q2 		$117K Buy
+1,304
New +$105K ﹤0.01% 2203
2019
Q1 		– Sell
-3,521
Closed -$495K – 2300
2018
Q4 		$495K Buy
3,521
+48
+1% +$8.1K 0.01% 1248
2018
Q3 		$887K Buy
3,473
+2,493
+254% +$689K 0.01% 1046
2018
Q2 		$250K Buy
+980
New +$242K ﹤0.01% 1458
2018
Q1 		– Sell
-860
Closed -$124K – 1928
2017
Q4 		$124K Buy
+860
New +$138K ﹤0.01% 1915
2017
Q1 		– Sell
-1,140
Closed -$161K – 1724
2016
Q4 		$161K Buy
+1,140
New +$154K 0.01% 1515

Other funds holding KPTI

UBS Group
UBS Group Zurich, Switzerland $765B AUM 28.39% 1-Year Est. Return
Acadian Asset Management
Acadian Asset Management Boston, Massachusetts $85.7B AUM 51.02% 1-Year Est. Return
STRS Ohio
STRS Ohio Columbus, Ohio $27.1B AUM 34.64% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.92T AUM 36.1% 1-Year Est. Return
Context Capital Management
Context Capital Management Lajolla, California $4.89B AUM 1.86% 1-Year Est. Return
Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.32T AUM 44.66% 1-Year Est. Return
BCM
BML Capital Management Zionsville, Indiana $188M AUM 88.51% 1-Year Est. Return
Simplex Trading
Simplex Trading Chicago, Illinois $184B AUM 51.71% 1-Year Est. Return
Nuveen
Nuveen Charlotte, North Carolina $420B AUM 34.97% 1-Year Est. Return
Bank of New York Mellon
Bank of New York Mellon New York $608B AUM 32.77% 1-Year Est. Return

Squarepoint's KPTI Position: Q3 2026 in Review

Squarepoint sold out of Karyopharm Therapeutics (KPTI) in Q3 2026, closing a stake of 63,801 shares — an estimated $623K sold.

Squarepoint first reported a position in KPTI in Q4 2016 and held it in 18 quarters. The position peaked at $2.31M in Q3 2020. 39 funds tracked by Wall St. Rank hold KPTI as of Q3 2026.

  • Squarepoint reported no remaining Karyopharm Therapeutics position as of Q3 2026 after selling out during the quarter.
  • Squarepoint sold 63,801 Karyopharm Therapeutics shares in Q3 2026, an estimated $623K.
  • Squarepoint first reported a position in Karyopharm Therapeutics in Q4 2016 and held it in 18 quarters.
  • Squarepoint's Karyopharm Therapeutics position peaked at $2.31M in Q3 2020.
  • 39 funds tracked by Wall St. Rank held Karyopharm Therapeutics as of Q3 2026.

Based on Squarepoint's 13F filing for Q3 2026, filed 9 Nov 2026.