We are live on ! Find out more
SSC

Spruce Street Capital Portfolio holdings

AUM $510M
This Fund
S&P 500
This Quarter Est. Return
+66.43%
1 Year Est. Return
–
3 Year Est. Return
–
5 Year Est. Return
–
10 Year Est. Return
–
AUM
$303M
AUM Growth
–
Cap. Flow
+$250M
Cap. Flow %
82.69%
Top 10 Hldgs %
70.8%
Holding
27
New
27
Increased
–
Reduced
–
Closed
–

Top Buys

Rank Stock Value
1
CDTX
Cidara Therapeutics
CDTX
+$37.5M
2
RLAY icon
Relay Therapeutics
RLAY
+$21.3M
3
PCVX icon
Vaxcyte
PCVX
+$17.9M
4
LBRX
LB Pharmaceuticals
LBRX
+$17.6M
5
KNSA icon
Kiniksa Pharmaceuticals
KNSA
+$17.4M

Top Sells

No sells this quarter

Sector Composition

Rank Sector Weight
1 Healthcare 100%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
IPSC icon
26
Century Therapeutics
IPSC
$384M
$1.41M 0.47%
+1,421,532
New +$867K
STRO icon
27
Sutro Biopharma
STRO
$340M
$875K 0.29%
+75,594
New +$717K
1
2

Similar funds

TCM
Towneley Capital Management Laguna Hills, California $509M AUM 17.24% 1-Year Est. Return
CRWM
Castle Rock Wealth Management Walnut Creek, California $509M AUM 36.93% 1-Year Est. Return
AG
Alibaba Group Causeway Bay, Hong Kong $509M AUM 25.62% 1-Year Est. Return
TGY2IT
Timothy G. Youngquist 2020 Irrevocable Trust Fort Myers, Florida $510M AUM
AWM
Aries Wealth Management Portland, Maine $509M AUM 25.6% 1-Year Est. Return
RPSA
Richard P. Slaughter Associates Austin, Texas $510M AUM 21.97% 1-Year Est. Return
WCP
Welch Capital Partners Harrison, New York $510M AUM 23.67% 1-Year Est. Return
MPPLM
Midwest Professional Planners Ltd (MPPL) Wausau, Wisconsin $510M AUM 49.02% 1-Year Est. Return

Spruce Street Capital's Q4 2025 Portfolio in Review

Q4 2025 is the first quarter with a 13F filing on record for Spruce Street Capital, which disclosed 27 positions worth $303M. Its ten largest holdings account for 71% of the portfolio.

Its largest position is Cidara Therapeutics: 232,269 shares worth $51.3M.

By sector, the portfolio is most concentrated in Healthcare at 100% of assets.

  • Spruce Street Capital's largest Q4 2025 buy was Cidara Therapeutics: 232,269 shares worth $51.3M.
  • Spruce Street Capital's ten largest holdings make up 71% of its $303M portfolio in Q4 2025.
  • Spruce Street Capital disclosed 27 positions in Q4 2025, its first 13F filing on record.

Based on Spruce Street Capital's 13F filing for Q4 2025, filed 13 Feb 2026.