We are live on ! Find out more
SFM

Sphera Funds Management Portfolio holdings

AUM $630M
1-Year Est. Return 108.65%
This Fund
S&P 500
This Quarter Est. Return
-0.94%
1 Year Est. Return
+108.65%
3 Year Est. Return
+217.64%
5 Year Est. Return
+342.91%
10 Year Est. Return
+2,254.45%
AUM
$553M
AUM Growth
-$75.2M
Cap. Flow
-$19.5M
Cap. Flow %
-3.53%
Top 10 Hldgs %
31.54%
Holding
133
New
18
Increased
30
Reduced
36
Closed
26

Top Buys

Rank Stock Value
1
GOOG icon
Alphabet (Google) Class C
GOOG
+$7.68M
2
ANNX icon
Annexon
ANNX
+$7.65M
3
ORA icon
Ormat Technologies
ORA
+$6.1M
4
SNDX icon
Syndax Pharmaceuticals
SNDX
+$5.93M
5
SEDG icon
SolarEdge
SEDG
+$5.77M

Top Sells

Rank Stock Value
1
AAPL icon
Apple
AAPL
+$14.2M
2
TEVA icon
Teva Pharmaceuticals
TEVA
+$10.2M
3
AMZN icon
Amazon
AMZN
+$8.8M
4
S icon
SentinelOne
S
+$6.62M
5
NICE icon
Nice
NICE
+$6.39M

Sector Composition

Rank Sector Weight
1 Healthcare 73.33%
2 Technology 15.86%
3 Communication Services 3.88%
4 Consumer Discretionary 2.48%
5 Utilities 0.97%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
CLYM
101
Climb Bio
CLYM
$681M
$453K 0.08%
251,935
+69,965
+38% +$253K
KYTX icon
102
Kyverna Therapeutics
KYTX
$444M
$444K 0.08%
118,758
-129,893
-52% -$622K
CGEN icon
103
Compugen
CGEN
$222M
$271K 0.05%
177,094
-50,000
-22% -$81.3K
LVTX
104
DELISTED
LAVA Therapeutics
LVTX
$120K 0.02%
126,328
-20,129
-14% -$31.6K
APLT
105
DELISTED
Applied Therapeutics
APLT
$42.8K 0.01%
50,000
-261,572
-84% -$1.64M
IMTXW
106
DELISTED
Immatics N.V. Warrants
IMTXW
$25.1K ﹤0.01%
100,000
– –
AAPL icon
107
Apple
AAPL
$4.54T
– –
-60,847
Closed -$14.2M
ADCT icon
108
ADC Therapeutics
ADCT
$134M
– –
-205,036
Closed -$646K
ADI icon
109
Analog Devices
ADI
$179B
– –
-6,660
Closed -$1.53M
ALNY icon
110
Alnylam Pharmaceuticals
ALNY
$27.5B
– –
-7,000
Closed -$1.93M
ARBE icon
111
Arbe Robotics
ARBE
$80.3M
– –
-43,165
Closed -$82.4K
ASML icon
112
ASML
ASML
$626B
– –
-2,840
Closed -$2.37M
CAPR icon
113
Capricor Therapeutics
CAPR
$223M
– –
-61,698
Closed -$938K
CRWD icon
114
CrowdStrike
CRWD
$194B
– –
-43,448
Closed -$3.05M
ENLT icon
115
Enlight Renewable Energy
ENLT
$11.8B
– –
-151,860
Closed -$2.57M
FDMT icon
116
4D Molecular Therapeutics
FDMT
$532M
– –
-48,702
Closed -$526K
GLBE icon
117
Global E Online
GLBE
$6.6B
– –
-64,384
Closed -$2.47M
GLUE icon
118
Monte Rosa Therapeutics
GLUE
$1.4B
– –
-118,103
Closed -$626K
KLAC icon
119
KLA
KLAC
$239B
– –
-27,750
Closed -$2.15M
NICE icon
120
CALL
Nice
NICE
$5.79B
– –
-32,100
Closed -$5.57M
NVDA icon
121
NVIDIA
NVDA
$4.86T
– –
-24,355
Closed -$2.96M
OTLK icon
122
Outlook Therapeutics
OTLK
$183M
– –
-413,545
Closed -$2.21M
PRAX icon
123
PUT
Praxis Precision Medicines
PRAX
$8.58B
– –
-52,000
Closed -$2.99M
PRME icon
124
Prime Medicine
PRME
$527M
– –
-76,456
Closed -$296K
PTCT icon
125
PTC Therapeutics
PTCT
$5.68B
– –
-118,345
Closed -$4.39M
2 3 4
5
6

Similar funds

VIM
Vancity Investment Management Vancouver, British Columbia, Canada $629M AUM 2.49% 1-Year Est. Return
KCMH
Keywise Capital Management (HK) Hong Kong $630M AUM 81.01% 1-Year Est. Return
FCFC
First Commonwealth Financial Corp Indiana, Pennsylvania $629M AUM 20.47% 1-Year Est. Return
BI
BlueSpruce Investments Chicago, Illinois $631M AUM 11.83% 1-Year Est. Return
PWW
Pettyjohn Wood & White Lynchburg, Virginia $628M AUM 20.96% 1-Year Est. Return
TTSTC
Texas Treasury Safekeeping Trust Company Austin, Texas $628M AUM 15.58% 1-Year Est. Return
SWP
Summit Wealth Partners Orlando, Florida $632M AUM 9.71% 1-Year Est. Return
EIM
Essex Investment Management Boston, Massachusetts $632M AUM 95.36% 1-Year Est. Return

Sphera Funds Management's Q4 2024 Portfolio in Review

As of Q4 2024, Sphera Funds Management held 133 positions worth $553M, down 12% from $628M the previous quarter. Its ten largest holdings account for 32% of the portfolio.

Sphera Funds Management withdrew a net $19.5M in Q4 2024, closing 26 positions and reducing 36 holdings. Its most notable exit was Apple, an estimated $14.2M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 73% of assets, up from 70% a quarter earlier, followed by Technology and Communication Services.

Against the trend, Sphera Funds Management opened a new position in Alphabet (Google) Class C worth $8.28M.

  • Sphera Funds Management's largest Q4 2024 buy was Alphabet (Google) Class C: 43,500 shares worth $8.28M.
  • Sphera Funds Management added most to Syndax Pharmaceuticals in Q4 2024, an estimated $5.93M increase.
  • Sphera Funds Management's biggest Q4 2024 reduction was Teva Pharmaceuticals, cutting an estimated $10.2M.
  • Sphera Funds Management fully exited Apple in Q4 2024, selling an estimated $14.2M.
  • Sphera Funds Management's ten largest holdings make up 32% of its $553M portfolio in Q4 2024.
  • Sphera Funds Management opened 18 new positions and closed 26 in Q4 2024.
  • Sphera Funds Management's portfolio value fell 12% quarter-over-quarter to $553M.

Based on Sphera Funds Management's 13F filing for Q4 2024, filed 14 Feb 2025.