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SFM

Sphera Funds Management Portfolio holdings

AUM $630M
1-Year Est. Return 108.65%
This Fund
S&P 500
This Quarter Est. Return
+3.76%
1 Year Est. Return
+108.65%
3 Year Est. Return
+217.64%
5 Year Est. Return
+342.91%
10 Year Est. Return
+2,254.45%
AUM
$910M
AUM Growth
-$281M
Cap. Flow
-$283M
Cap. Flow %
-31.16%
Top 10 Hldgs %
40.89%
Holding
141
New
25
Increased
18
Reduced
31
Closed
51

Top Buys

Rank Stock Value
1
MRK icon
Merck
MRK
+$27.6M
2
AMZN icon
Amazon
AMZN
+$13.8M
3
FIVN icon
FIVE9
FIVN
+$12.7M
4
SNY icon
Sanofi
SNY
+$11.9M
5
S icon
SentinelOne
S
+$11.7M

Top Sells

Rank Stock Value
1
LLY icon
Eli Lilly
LLY
+$47.9M
2
PFE icon
Pfizer
PFE
+$43.5M
3
ABBV icon
AbbVie
ABBV
+$15.6M
4
AZN icon
AstraZeneca
AZN
+$13.9M
5
JNJ icon
Johnson & Johnson
JNJ
+$13.7M

Sector Composition

Rank Sector Weight
1 Healthcare 68.66%
2 Technology 9.03%
3 Consumer Discretionary 4.71%
4 Communication Services 2.8%
5 Industrials 2.43%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
DVAX
101
DELISTED
Dynavax Technologies
DVAX
– –
-198,880
Closed -$3.82M
ERAS icon
102
Erasca
ERAS
$6.3B
– –
-70,000
Closed -$1.49M
FOLD
103
DELISTED
Amicus Therapeutics
FOLD
– –
-491,159
Closed -$4.69M
GLUE icon
104
Monte Rosa Therapeutics
GLUE
$1.4B
– –
-119,647
Closed -$2.67M
HIPO icon
105
Hippo Holdings
HIPO
$830M
– –
-22,599
Closed -$2.64M
IMCR icon
106
Immunocore
IMCR
$1.72B
– –
-4,235
Closed -$157K
IONS icon
107
CALL
Ionis Pharmaceuticals
IONS
$8.6B
– –
-350,000
Closed -$11.7M
IONS icon
108
Ionis Pharmaceuticals
IONS
$8.6B
– –
-22,000
Closed -$738K
IWM icon
109
PUT
iShares Russell 2000 ETF
IWM
$79.8B
– –
-210,000
Closed -$45.9M
KRNT icon
110
Kornit Digital
KRNT
$705M
– –
-72,076
Closed -$10.4M
MOLN
111
Molecular Partners
MOLN
– –
-80,555
Closed -$1.58M
NICE icon
112
Nice
NICE
$5.79B
– –
-37,786
Closed -$10.7M
NKE icon
113
Nike
NKE
$61.9B
– –
-65,000
Closed -$9.44M
NTLA icon
114
Intellia Therapeutics
NTLA
$1.49B
– –
-23,647
Closed -$3.17M
PTGX icon
115
Protagonist Therapeutics
PTGX
$8.79B
– –
-260,379
Closed -$8.23M
QURE icon
116
uniQure
QURE
$3.03B
– –
-172,000
Closed -$4.93M
RPTX
117
DELISTED
Repare Therapeutics
RPTX
– –
-100,391
Closed -$2.63M
RUN icon
118
Sunrun
RUN
$2.34B
– –
-189,000
Closed -$8.84M
SEDG icon
119
SolarEdge
SEDG
$2.51B
– –
-50,000
Closed -$13.3M
TEVA icon
120
CALL
Teva Pharmaceuticals
TEVA
$40.8B
– –
-1,050,000
Closed -$10.2M
TWLO icon
121
Twilio
TWLO
$30B
– –
-35,500
Closed -$11.3M
UPWK icon
122
Upwork
UPWK
$1.13B
– –
-10,000
Closed -$450K
XBI icon
123
PUT
State Street SPDR S&P Biotech ETF
XBI
$9.95B
– –
-400,000
Closed -$50.3M
XENE icon
124
Xenon Pharmaceuticals
XENE
$6.06B
– –
-373,510
Closed -$5.71M
ACHL
125
DELISTED
Achilles Therapeutics
ACHL
– –
-242,500
Closed -$1.89M
2 3 4
5
6

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KCMH
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FCFC
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BI
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PWW
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TTSTC
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SWP
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EIM
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Sphera Funds Management's Q4 2021 Portfolio in Review

As of Q4 2021, Sphera Funds Management held 141 positions worth $910M, down 24% from $1.19B the previous quarter. Its ten largest holdings account for 41% of the portfolio.

Sphera Funds Management withdrew a net $283M in Q4 2021, closing 51 positions and reducing 31 holdings. Its most notable exit was SolarEdge, an estimated $13.3M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 69% of assets, up from 63% a quarter earlier, followed by Technology and Consumer Discretionary.

Against the trend, Sphera Funds Management opened a new position in Merck worth $26.6M.

  • Sphera Funds Management's largest Q4 2021 buy was Merck: 346,423 shares worth $26.6M.
  • Sphera Funds Management added most to Amazon in Q4 2021, an estimated $13.8M increase.
  • Sphera Funds Management's biggest Q4 2021 reduction was Eli Lilly, cutting an estimated $47.9M.
  • Sphera Funds Management fully exited SolarEdge in Q4 2021, selling an estimated $13.3M.
  • Sphera Funds Management's ten largest holdings make up 41% of its $910M portfolio in Q4 2021.
  • Sphera Funds Management opened 25 new positions and closed 51 in Q4 2021.
  • Sphera Funds Management's portfolio value fell 24% quarter-over-quarter to $910M.

Based on Sphera Funds Management's 13F filing for Q4 2021, filed 14 Feb 2022.