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Sarissa Capital Management Portfolio holdings

AUM $158M
1-Year Est. Return 103.7%
This Fund
S&P 500
This Quarter Est. Return
+6.75%
1 Year Est. Return
+103.7%
3 Year Est. Return
+58.62%
5 Year Est. Return
+92.85%
10 Year Est. Return
+667.68%
AUM
$158M
AUM Growth
-$65.3M
Cap. Flow
-$78.3M
Cap. Flow %
-49.65%
Top 10 Hldgs %
100%
Holding
9
New
–
Increased
1
Reduced
5
Closed
–

Top Buys

1
BHVN icon
Biohaven
BHVN
+$547K

Top Sells

1
IRWD icon
Ironwood Pharmaceuticals
IRWD
+$27.6M
2
NBIX icon
Neurocrine Biosciences
NBIX
+$24.8M
3
INVA icon
Innoviva
INVA
+$14.8M
4
CYTK icon
Cytokinetics
CYTK
+$10.7M
5
LNTH icon
Lantheus
LNTH
+$1.04M

Sector Composition

1 Healthcare 100%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
INVA icon
1
Innoviva
INVA
$1.6B
$49.7M 31.5%
2,130,950
-685,072
-24% -$14.8M
IRWD icon
2
Ironwood Pharmaceuticals
IRWD
$635M
$32.3M 20.46%
9,188,635
-6,730,800
-42% -$27.6M
AMRN
3
Amarin Corp
AMRN
$292M
$24.2M 15.35%
1,673,395
– –
NBIX icon
4
Neurocrine Biosciences
NBIX
$17.2B
$15.4M 9.74%
116,533
-186,618
-62% -$24.8M
CYTK icon
5
Cytokinetics
CYTK
$10.9B
$15.1M 9.56%
228,623
-167,734
-42% -$10.7M
LNTH icon
6
Lantheus
LNTH
$7B
$12.7M 8.03%
166,919
-14,531
-8% -$1.04M
BHVN icon
7
Biohaven
BHVN
$2.32B
$4.76M 3.02%
563,184
+50,000
+10% +$547K
REGN icon
8
Regeneron Pharmaceuticals
REGN
$70.9B
$3.24M 2.05%
4,190
– –
VOR icon
9
Vor Biopharma
VOR
$980M
$453K 0.29%
25,399
– –

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DAM
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PCP
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RA
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FI
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PWA
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Sarissa Capital Management's Q1 2026 Portfolio in Review

As of Q1 2026, Sarissa Capital Management held 9 positions worth $158M, down 29% from $223M the previous quarter. Its ten largest holdings account for 100% of the portfolio.

Sarissa Capital Management withdrew a net $78.3M in Q1 2026, reducing 5 holdings. Its largest reduction was Ironwood Pharmaceuticals, cutting an estimated $27.6M.

By sector, the portfolio is most concentrated in Healthcare at 100% of assets, unchanged from a quarter earlier.

Against the trend, Sarissa Capital Management added an estimated $547K to Biohaven.

  • Sarissa Capital Management added most to Biohaven in Q1 2026, an estimated $547K increase.
  • Sarissa Capital Management's biggest Q1 2026 reduction was Ironwood Pharmaceuticals, cutting an estimated $27.6M.
  • Sarissa Capital Management's ten largest holdings make up 100% of its $158M portfolio in Q1 2026.
  • Sarissa Capital Management opened 0 new positions and closed 0 in Q1 2026.
  • Sarissa Capital Management's portfolio value fell 29% quarter-over-quarter to $158M.

Based on Sarissa Capital Management's 13F filing for Q1 2026, filed 15 May 2026.