Renaissance Technologies
OPRX icon

Renaissance Technologies’s OptimizeRx OPRX Stock Holding History

Renaissance Technologies’s Portfolio OPRX Stock Details OPRX Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$959K Sell
167,700
-49,156
-23% -$283K ﹤0.01% 2330
2026
Q1 		$1.36M Buy
216,856
+187,278
+633% +$1.74M ﹤0.01% 2110
2025
Q4 		$363K Sell
29,578
-78,322
-73% -$1.28M ﹤0.01% 2704
2025
Q3 		$2.21M Buy
107,900
+30,193
+39% +$479K ﹤0.01% 2002
2025
Q2 		$1.05M Buy
+77,707
New +$850K ﹤0.01% 2494
2024
Q4 		– Sell
-67,500
Closed -$521K – 3810
2024
Q3 		$521K Sell
67,500
-74,646
-53% -$663K ﹤0.01% 2775
2024
Q2 		$1.42M Buy
142,146
+71,700
+102% +$788K ﹤0.01% 2106
2024
Q1 		$856K Sell
70,446
-21,899
-24% -$318K ﹤0.01% 2578
2023
Q4 		$1.32M Buy
+92,345
New +$886K ﹤0.01% 2219
2023
Q3 		– Sell
-63,500
Closed -$907K – 3973
2023
Q2 		$907K Sell
63,500
-120,900
-66% -$1.72M ﹤0.01% 2528
2023
Q1 		$2.7M Buy
184,400
+143,417
+350% +$2.4M ﹤0.01% 1838
2022
Q4 		$689K Buy
40,983
+8,783
+27% +$152K ﹤0.01% 2750
2022
Q3 		$477K Sell
32,200
-13,824
-30% -$273K ﹤0.01% 2948
2022
Q2 		$1.26M Sell
46,024
-43,976
-49% -$1.3M ﹤0.01% 2552
2022
Q1 		$3.39M Buy
90,000
+81,300
+934% +$3.6M ﹤0.01% 1842
2021
Q4 		$540K Buy
+8,700
New +$659K ﹤0.01% 3039
2019
Q3 		– Sell
-32,100
Closed -$520K – 3628
2019
Q2 		$520K Buy
+32,100
New +$433K ﹤0.01% 2979

Other funds holding OPRX

WCA
Whetstone Capital Advisors Shawnee Mission, Kansas $380M AUM 20.01% 1-Year Est. Return
RA
Royce & Associates New York $12.4B AUM 64.17% 1-Year Est. Return
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
KCM
Kennedy Capital Management St Louis, Missouri $5.65B AUM 61.31% 1-Year Est. Return
RHJA
Rice Hall James & Associates San Diego, California $2.05B AUM 43.16% 1-Year Est. Return
William Blair & Company
William Blair & Company Chicago, Illinois $38.4B AUM 25.71% 1-Year Est. Return
AQR Capital Management
AQR Capital Management Greenwich, Connecticut $287B AUM 42.33% 1-Year Est. Return
Dimensional Fund Advisors
Dimensional Fund Advisors Austin, Texas $552B AUM 44.19% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
PHP
Parkman Healthcare Partners Stamford, Connecticut $977M AUM 110.37% 1-Year Est. Return

Renaissance Technologies's OPRX Position: Q2 2026 in Review

Renaissance Technologies reduced its OptimizeRx (OPRX) stake by 23% in Q2 2026, selling an estimated $283K and leaving 167,700 shares worth $959K. The position accounts for ﹤0.01% of the portfolio, ranked #2330.

Renaissance Technologies first reported a position in OPRX in Q2 2019 and has held it in 17 quarters since. The position peaked at $3.39M in Q1 2022. 113 funds tracked by Wall St. Rank hold OPRX as of Q2 2026.

  • Renaissance Technologies held 167,700 shares of OptimizeRx worth $959K as of Q2 2026.
  • Renaissance Technologies sold 49,156 OptimizeRx shares in Q2 2026, an estimated $283K.
  • OptimizeRx made up ﹤0.01% of Renaissance Technologies's portfolio in Q2 2026, its #2330 holding.
  • Renaissance Technologies first reported a position in OptimizeRx in Q2 2019 and has held it in 17 quarters since.
  • Renaissance Technologies's OptimizeRx position peaked at $3.39M in Q1 2022.
  • 113 funds tracked by Wall St. Rank held OptimizeRx as of Q2 2026.

Based on Renaissance Technologies's 13F filing for Q2 2026, filed 13 Aug 2026.