Renaissance Technologies
IRD

Renaissance Technologies’s Opus Genetics IRD Stock Holding History

Renaissance Technologies’s Portfolio IRD Stock Details IRD Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$333K Sell
73,209
-53,100
-42% -$184K ﹤0.01% 2761
2025
Q4 		$254K Sell
126,309
-47,500
-27% -$96.4K ﹤0.01% 2824
2025
Q3 		$287K Buy
173,809
+20,500
+13% +$25.5K ﹤0.01% 3014
2025
Q2 		$144K Buy
153,309
+29,600
+24% +$27.4K ﹤0.01% 3236
2025
Q1 		$121K Sell
123,709
-21,800
-15% -$24.4K ﹤0.01% 3162
2024
Q4 		$173K Buy
145,509
+74,900
+106% +$86K ﹤0.01% 3201
2024
Q3 		$92.5K Buy
70,609
+28,909
+69% +$44.5K ﹤0.01% 3269
2024
Q2 		$63.8K Sell
41,700
-93,600
-69% -$162K ﹤0.01% 3256
2024
Q1 		$272K Buy
135,300
+111,075
+459% +$282K ﹤0.01% 3122
2023
Q4 		$73K Buy
+24,225
New +$71.6K ﹤0.01% 3381
2023
Q3 		– Sell
-99,600
Closed -$432K – 4194
2023
Q2 		$432K Sell
99,600
-90,369
-48% -$429K ﹤0.01% 2953
2023
Q1 		$712K Buy
189,969
+469
+0.2% +$1.68K ﹤0.01% 2681
2022
Q4 		$669K Sell
189,500
-17,401
-8% -$45.8K ﹤0.01% 2764
2022
Q3 		$416K Buy
206,901
+8,711
+4% +$18.8K ﹤0.01% 3036
2022
Q2 		$381K Buy
+198,190
New +$451K ﹤0.01% 3314
2022
Q1 		– Sell
-19,361
Closed -$72K – 4545
2021
Q4 		$72K Buy
+19,361
New +$77.6K ﹤0.01% 3742
2021
Q3 		– Sell
-35,529
Closed -$188K – 3917
2021
Q2 		$188K Sell
35,529
-78,091
-69% -$388K ﹤0.01% 3260
2021
Q1 		$660K Buy
113,620
+39,800
+54% +$370K ﹤0.01% 2800
2020
Q4 		$479K Buy
73,820
+15,494
+27% +$107K ﹤0.01% 2838
2020
Q3 		$485K Buy
58,326
+6,001
+11% +$58.4K ﹤0.01% 2819
2020
Q2 		$594K Buy
52,325
+5,884
+13% +$54.1K ﹤0.01% 2809
2020
Q1 		$334K Buy
46,441
+9,358
+25% +$81.3K ﹤0.01% 2932
2019
Q4 		$283K Buy
37,083
+9,807
+36% +$73.9K ﹤0.01% 3086
2019
Q3 		$224K Buy
27,276
+5,721
+27% +$79.6K ﹤0.01% 3117
2019
Q2 		$445K Buy
21,555
+8,651
+67% +$196K ﹤0.01% 3042
2019
Q1 		$316K Buy
12,904
+10,714
+489% +$355K ﹤0.01% 3072
2018
Q4 		$98K Buy
+2,190
New +$128K ﹤0.01% 3236
2018
Q2 		– Sell
-364
Closed -$26K – 3582
2018
Q1 		$26K Sell
364
-106
-23% -$9.63K ﹤0.01% 3328
2017
Q4 		$46K Sell
470
-6,703
-93% -$681K ﹤0.01% 3269
2017
Q3 		$833K Sell
7,173
-3,354
-32% -$362K ﹤0.01% 2632
2017
Q2 		$1.45M Sell
10,527
-1,470
-12% -$286K ﹤0.01% 2427
2017
Q1 		$2.94M Buy
11,997
+1,796
+18% +$233K ﹤0.01% 2025
2016
Q4 		$695K Buy
10,201
+3,530
+53% +$287K ﹤0.01% 2671
2016
Q3 		$672K Buy
6,671
+1,764
+36% +$213K ﹤0.01% 2724
2016
Q2 		$592K Buy
4,907
+1,395
+40% +$196K ﹤0.01% 2739
2016
Q1 		$556K Buy
3,512
+874
+33% +$145K ﹤0.01% 2818
2015
Q4 		$460K Buy
2,638
+898
+52% +$191K ﹤0.01% 2762
2015
Q3 		$434K Buy
1,740
+540
+45% +$147K ﹤0.01% 2666
2015
Q2 		$350K Buy
1,200
+596
+99% +$202K ﹤0.01% 2830
2015
Q1 		$212K Buy
604
+281
+87% +$102K ﹤0.01% 2871
2014
Q4 		$108K Buy
+323
New +$112K ﹤0.01% 2794

Other funds holding IRD

CP
Caligan Partners New York $1.5B AUM 518.95% 1-Year Est. Return
Adage Capital Partners
Adage Capital Partners Boston, Massachusetts $64.8B AUM 42.7% 1-Year Est. Return
BCM
BIOS Capital Management Fort Worth, Texas $52.9M AUM 30.51% 1-Year Est. Return
Balyasny Asset Management
Balyasny Asset Management Chicago, Illinois $77.1B AUM 42.89% 1-Year Est. Return
Millennium Management
Millennium Management New York $240B AUM 35.51% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
Marshall Wace
Marshall Wace London, United Kingdom $100B AUM 35.1% 1-Year Est. Return
BCM
Boxer Capital Management San Diego, California $762M AUM 1,125.36% 1-Year Est. Return
ACM
ADAR1 Capital Management Austin, Texas $1.7B AUM 340.85% 1-Year Est. Return
PA
Perceptive Advisors New York $5.12B AUM 314.02% 1-Year Est. Return

Renaissance Technologies's IRD Position: Q1 2026 in Review

Renaissance Technologies reduced its Opus Genetics (IRD) stake by 42% in Q1 2026, selling an estimated $184K and leaving 73,209 shares worth $333K. The position accounts for ﹤0.01% of the portfolio, ranked #2761.

Renaissance Technologies first reported a position in IRD in Q4 2014 and has held it in 41 quarters since. The position peaked at $2.94M in Q1 2017. 79 funds tracked by Wall St. Rank hold IRD as of Q1 2026.

  • Renaissance Technologies held 73,209 shares of Opus Genetics worth $333K as of Q1 2026.
  • Renaissance Technologies sold 53,100 Opus Genetics shares in Q1 2026, an estimated $184K.
  • Opus Genetics made up ﹤0.01% of Renaissance Technologies's portfolio in Q1 2026, its #2761 holding.
  • Renaissance Technologies first reported a position in Opus Genetics in Q4 2014 and has held it in 41 quarters since.
  • Renaissance Technologies's Opus Genetics position peaked at $2.94M in Q1 2017.
  • 79 funds tracked by Wall St. Rank held Opus Genetics as of Q1 2026.

Based on Renaissance Technologies's 13F filing for Q1 2026, filed 14 May 2026.