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Prosight Management Portfolio holdings

AUM $580M
1-Year Est. Return 29.81%
This Fund
S&P 500
This Quarter Est. Return
-14.49%
1 Year Est. Return
+29.81%
3 Year Est. Return
+39.55%
5 Year Est. Return
-6.93%
10 Year Est. Return
–
AUM
$304M
AUM Growth
-$57.5M
Cap. Flow
+$7.69M
Cap. Flow %
2.53%
Top 10 Hldgs %
59.64%
Holding
42
New
6
Increased
17
Reduced
13
Closed
4

Top Buys

Rank Stock Value
1
JANX icon
Janux Therapeutics
JANX
+$13.6M
2
TECX
Tectonic Therapeutic
TECX
+$13M
3
ARGX icon
argenx
ARGX
+$8.65M
4
ISRG icon
Intuitive Surgical
ISRG
+$7.74M
5
LKFT
Lakefront Biotherapeutics American Depositary Shares
LKFT
+$7.33M

Top Sells

Rank Stock Value
1
ACHC icon
Acadia Healthcare
ACHC
+$15.3M
2
ABCL icon
AbCellera Biologics
ABCL
+$13M
3
BBIO icon
BridgeBio Pharma
BBIO
+$13M
4
ZBH icon
Zimmer Biomet
ZBH
+$8.45M
5
SDGR icon
Schrodinger
SDGR
+$7.55M

Sector Composition

Rank Sector Weight
1 Healthcare 100%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
LKFT
1
Lakefront Biotherapeutics American Depositary Shares
LKFT
$1.89B
$33M 10.85%
1,314,898
+289,898
+28% +$7.33M
MGTX icon
2
MeiraGTx Holdings
MGTX
$1.33B
$25M 8.22%
3,691,546
-699,291
-16% -$4.7M
BBIO icon
3
BridgeBio Pharma
BBIO
$15B
$21.1M 6.93%
610,000
-385,000
-39% -$13M
JANX icon
4
Janux Therapeutics
JANX
$1.1B
$18.6M 6.12%
689,901
+360,133
+109% +$13.6M
ROIV icon
5
Roivant Sciences
ROIV
$25.1B
$18.4M 6.05%
1,826,163
+326,163
+22% +$3.53M
MIRM icon
6
Mirum Pharmaceuticals
MIRM
$5.94B
$15.5M 5.08%
343,326
-107,801
-24% -$5.08M
KURA icon
7
Kura Oncology
KURA
$1.13B
$13.7M 4.51%
2,078,315
+753,315
+57% +$5.87M
ADCT icon
8
ADC Therapeutics
ADCT
$146M
$13.5M 4.42%
9,543,004
+28,004
+0.3% +$47.6K
ZYME icon
9
Zymeworks
ZYME
$2.02B
$11.4M 3.75%
957,229
+137,229
+17% +$1.87M
FOLD
10
DELISTED
Amicus Therapeutics
FOLD
$11.3M 3.7%
1,379,383
+459,383
+50% +$4.25M
ICLR icon
11
Icon
ICLR
$13.1B
$10.5M 3.46%
60,099
-24,901
-29% -$4.83M
RCKT icon
12
Rocket Pharmaceuticals
RCKT
$424M
$9.87M 3.24%
1,480,000
+391,294
+36% +$3.87M
ACHC icon
13
Acadia Healthcare
ACHC
$2.66B
$8.79M 2.89%
290,000
-402,000
-58% -$15.3M
ARGX icon
14
argenx
ARGX
$64B
$8.11M 2.66%
+13,700
New +$8.65M
SDGR icon
15
Schrodinger
SDGR
$1.47B
$7.6M 2.5%
385,000
-335,500
-47% -$7.55M
SNDX icon
16
Syndax Pharmaceuticals
SNDX
$1.74B
$7.48M 2.46%
609,252
-10,748
-2% -$152K
TECX
17
Tectonic Therapeutic
TECX
$696M
$7.06M 2.32%
+398,885
New +$13M
ISRG icon
18
Intuitive Surgical
ISRG
$132B
$6.93M 2.28%
+14,000
New +$7.74M
STTK icon
19
Shattuck Labs
STTK
$707M
$6.31M 2.07%
6,638,935
– –
ABCL icon
20
AbCellera Biologics
ABCL
$3.68B
$6.28M 2.06%
2,815,652
-4,534,348
-62% -$13M
IMVT icon
21
Immunovant
IMVT
$8.51B
$6.15M 2.02%
360,000
+54,477
+18% +$1.14M
PRTA icon
22
Prothena Corp
PRTA
$479M
$5.05M 1.66%
408,122
-10,000
-2% -$141K
LIVN icon
23
LivaNova
LIVN
$4.43B
$5M 1.64%
127,300
+57,300
+82% +$2.57M
HAE icon
24
Haemonetics
HAE
$4.73B
$4.16M 1.37%
65,400
+18,700
+40% +$1.27M
BPMC
25
DELISTED
Blueprint Medicines
BPMC
$3.23M 1.06%
36,512
-30,488
-46% -$2.97M
1
2

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CMA
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RIS
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MFS
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GFI
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Prosight Management's Q1 2025 Portfolio in Review

As of Q1 2025, Prosight Management held 42 positions worth $304M, down 16% from $362M the previous quarter. Its ten largest holdings account for 60% of the portfolio.

Prosight Management's Q1 2025 filing shows 6 new, 17 increased, 13 reduced and 4 closed positions. Its largest new stake was Tectonic Therapeutic: 398,885 shares worth $7.06M. The largest sale was Acadia Healthcare, an estimated $15.3M.

By sector, the portfolio is most concentrated in Healthcare at 100% of assets, up from 99% a quarter earlier.

  • Prosight Management's largest Q1 2025 buy was Tectonic Therapeutic: 398,885 shares worth $7.06M.
  • Prosight Management added most to Janux Therapeutics in Q1 2025, an estimated $13.6M increase.
  • Prosight Management's biggest Q1 2025 reduction was Acadia Healthcare, cutting an estimated $15.3M.
  • Prosight Management fully exited Zimmer Biomet in Q1 2025, selling an estimated $8.45M.
  • Prosight Management's ten largest holdings make up 60% of its $304M portfolio in Q1 2025.
  • Prosight Management opened 6 new positions and closed 4 in Q1 2025.
  • Prosight Management's portfolio value fell 16% quarter-over-quarter to $304M.

Based on Prosight Management's 13F filing for Q1 2025, filed 15 May 2025.