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Perceptive Advisors Portfolio holdings

AUM $6.66B
1-Year Est. Return 360.84%
This Fund
S&P 500
This Quarter Est. Return
+32.47%
1 Year Est. Return
+360.84%
3 Year Est. Return
+1,707.27%
5 Year Est. Return
+3,210.42%
10 Year Est. Return
+53,055.89%
AUM
$6.66B
AUM Growth
+$1.54B
Cap. Flow
+$235M
Cap. Flow %
3.53%
Top 10 Hldgs %
47.3%
Holding
121
New
27
Increased
30
Reduced
28
Closed
12

Sector Composition

Rank Sector Weight
1 Healthcare 96.3%
2 Miscellaneous 3.58%
3 Financials 0.12%

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Perceptive Advisors's Q2 2026 Portfolio in Review

As of Q2 2026, Perceptive Advisors held 121 positions worth $6.66B, up 30% from $5.12B the previous quarter. Its ten largest holdings account for 47% of the portfolio.

Perceptive Advisors deployed $235M of net new capital in Q2 2026, opening 27 new positions and adding to 30 existing holdings. Its largest new stake was Kardigan Inc: 8,200,662 shares worth $196M.

By sector, the portfolio is most concentrated in Healthcare at 96% of assets, down from 99% a quarter earlier, followed by Miscellaneous and Financials.

On the sell side, the largest reduction was Ascendis Pharma A/S, an estimated $85.9M trimmed.

  • Perceptive Advisors's largest Q2 2026 buy was Kardigan Inc: 8,200,662 shares worth $196M.
  • Perceptive Advisors added most to Tango Therapeutics in Q2 2026, an estimated $63.5M increase.
  • Perceptive Advisors's biggest Q2 2026 reduction was Ascendis Pharma A/S, cutting an estimated $85.9M.
  • Perceptive Advisors fully exited Centessa Pharmaceuticals in Q2 2026, selling an estimated $209M.
  • Perceptive Advisors's ten largest holdings make up 47% of its $6.66B portfolio in Q2 2026.
  • Perceptive Advisors opened 27 new positions and closed 12 in Q2 2026.
  • Perceptive Advisors's portfolio value rose 30% quarter-over-quarter to $6.66B.

Based on Perceptive Advisors's 13F filing for Q2 2026, filed 14 Aug 2026.