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Perceptive Advisors Portfolio holdings

AUM $6.66B
1-Year Est. Return 360.84%
This Fund
S&P 500
This Quarter Est. Return
-1.57%
1 Year Est. Return
+360.84%
3 Year Est. Return
+1,707.27%
5 Year Est. Return
+3,210.42%
10 Year Est. Return
+53,055.89%
AUM
$6.49B
AUM Growth
-$396M
Cap. Flow
-$220M
Cap. Flow %
-3.39%
Top 10 Hldgs %
43.16%
Holding
163
New
23
Increased
16
Reduced
43
Closed
16

Sector Composition

Rank Sector Weight
1 Healthcare 85.98%
2 Miscellaneous 13.04%
3 Financials 0.8%
4 Industrials 0.09%
5 Consumer Staples 0.06%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
CYPH
51
Cypherpunk Technologies Inc
CYPH
$239M
$27.5M 0.42%
847,650
ESTA icon
52
Establishment Labs
ESTA
$2.13B
$27.4M 0.42%
405,541
-100,000
-20% -$6.99M
COGT icon
53
Cogent Biosciences
COGT
$5.68B
$27.4M 0.42%
3,188,750
CMAX
54
DELISTED
CareMax, Inc. Class A Common Stock
CMAX
$27.3M 0.42%
118,318
+5,485
+5% +$1.3M
MGNX icon
55
MacroGenics
MGNX
$257M
$26.7M 0.41%
1,665,243
-482,817
-22% -$9.09M
VERU icon
56
Veru
VERU
$39.9M
$26.2M 0.4%
445,134
NUVB icon
57
Nuvation Bio
NUVB
$2.04B
$24.8M 0.38%
2,920,823
-120,181
-4% -$1.1M
LUNG icon
58
Pulmonx
LUNG
$82M
$24.4M 0.38%
+762,304
New +$27.8M
NVTA
59
DELISTED
Invitae Corporation
NVTA
$24.2M 0.37%
1,584,585
-2,339,156
-60% -$50.6M
SLDB icon
60
Solid Biosciences
SLDB
$897M
$23.5M 0.36%
894,170
PYXS icon
61
Pyxis Oncology
PYXS
$278M
$21.3M 0.33%
+1,944,114
New +$22.3M
HLTH
62
DELISTED
Cue Health Inc. Common Stock
HLTH
$21.2M 0.33%
1,580,607
UTHR icon
63
United Therapeutics
UTHR
$21.5B
$20.3M 0.31%
94,064
-47,636
-34% -$9.35M
VRNA
64
DELISTED
Verona Pharma
VRNA
$19.3M 0.3%
2,867,510
-21,379
-0.7% -$109K
SNCE
65
DELISTED
Science 37 Holdings, Inc. Common Stock
SNCE
$18.7M 0.29%
75,000
+60,000
+400% +$13.3M
ATNX
66
DELISTED
Athenex, Inc. Common Stock
ATNX
$18.4M 0.28%
676,623
TMCI icon
67
Treace Medical Concepts
TMCI
$298M
$18.3M 0.28%
980,186
-255,700
-21% -$5.28M
HCAT icon
68
Health Catalyst
HCAT
$129M
$18M 0.28%
454,004
-135,000
-23% -$6.15M
DICE
69
DELISTED
DICE Therapeutics, Inc. Common Stock
DICE
$17.8M 0.28%
+704,885
New +$20.7M
SLGC
70
DELISTED
SomaLogic, Inc. Class A Common Stock
SLGC
$17.5M 0.27%
1,500,000
-550,000
-27% -$6.59M
ADMA icon
71
ADMA Biologics
ADMA
$1.93B
$16.8M 0.26%
11,933,387
-1,328,988
-10% -$1.75M
NUVL
72
DELISTED
Nuvalent
NUVL
$14.3M 0.22%
750,000
LYRA
73
DELISTED
LYRA THERAPEUTICS INC
LYRA
$14.1M 0.22%
64,451
VTRS icon
74
Viatris
VTRS
$19.1B
$13.6M 0.21%
1,004,419
FLNA
75
PUT
Filana Therapeutics
FLNA
$33.6M
$13.1M 0.2%
300,000
+200,000
+200% +$10.5M

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Perceptive Advisors's Q4 2021 Portfolio in Review

As of Q4 2021, Perceptive Advisors held 163 positions worth $6.49B, down 5.7% from $6.88B the previous quarter. Its ten largest holdings account for 43% of the portfolio.

Perceptive Advisors withdrew a net $220M in Q4 2021, closing 16 positions and reducing 43 holdings. Its most notable exit was Atea Pharmaceuticals, an estimated $79.2M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 86% of assets, down from 86% a quarter earlier, followed by Miscellaneous and Financials.

Against the trend, Perceptive Advisors opened a new position in LianBio American Depositary Shares worth $347M.

  • Perceptive Advisors's largest Q4 2021 buy was LianBio American Depositary Shares: 56,319,960 shares worth $347M.
  • Perceptive Advisors added most to Apellis Pharmaceuticals in Q4 2021, an estimated $32.9M increase.
  • Perceptive Advisors's biggest Q4 2021 reduction was Invitae Corporation, cutting an estimated $50.6M.
  • Perceptive Advisors fully exited Atea Pharmaceuticals in Q4 2021, selling an estimated $79.2M.
  • Perceptive Advisors's ten largest holdings make up 43% of its $6.49B portfolio in Q4 2021.
  • Perceptive Advisors opened 23 new positions and closed 16 in Q4 2021.
  • Perceptive Advisors's portfolio value fell 5.7% quarter-over-quarter to $6.49B.

Based on Perceptive Advisors's 13F filing for Q4 2021, filed 14 Feb 2022.