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MGB

Mass General Brigham Portfolio holdings

AUM $361M
This Fund
S&P 500
This Quarter Est. Return
+5.22%
1 Year Est. Return
–
3 Year Est. Return
–
5 Year Est. Return
–
10 Year Est. Return
–
AUM
$810M
AUM Growth
–
Cap. Flow
+$797M
Cap. Flow %
98.38%
Top 10 Hldgs %
100%
Holding
7
New
7
Increased
–
Reduced
–
Closed
–
Avg Time Held
2 quarters
Top 10 Avg Time Held
0.9 quarters
Top 20 Avg Time Held
0.9 quarters

Top Buys

Rank Stock Value
1
ACWI icon
iShares MSCI ACWI ETF
ACWI
+$648M
2
KRMN
Karman Holdings
KRMN
+$113M
3
RVMD icon
Revolution Medicines
RVMD
+$22.6M
4
MAZE
Maze Therapeutics
MAZE
+$8.25M
5
TNGX icon
Tango Therapeutics
TNGX
+$3.05M

Top Sells

No sells this quarter

Sector Composition

Rank Sector Weight
1 Miscellaneous 80.62%
2 Industrials 14.11%
3 Healthcare 5.14%
4 Technology 0.13%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow Held Since
ACWI icon
1
iShares MSCI ACWI ETF
ACWI
$33.1B
$653M 80.62%
+4,613,955
New +$648M
2025 Q4
0 quarters
KRMN
2
Karman Holdings
KRMN
$4.52B
$114M 14.11%
+1,562,054
New +$113M
2025 Q4
0 quarters
RVMD icon
3
Revolution Medicines
RVMD
$44.3B
$27.4M 3.38%
+344,091
New +$22.6M
2024 Q1
7 quarters
MAZE
4
Maze Therapeutics
MAZE
$1.47B
$9.94M 1.23%
+239,994
New +$8.25M
2025 Q4
0 quarters
TNGX icon
5
Tango Therapeutics
TNGX
$3.92B
$3.14M 0.39%
+354,192
New +$3.05M
2024 Q1
7 quarters
MDLN
6
Medline Inc
MDLN
$31.2B
$1.1M 0.14%
+26,294
New +$1.11M
2025 Q4
0 quarters
RBRK icon
7
Rubrik
RBRK
$24.6B
$1.07M 0.13%
+14,000
New +$1.07M
2025 Q4
0 quarters

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HP
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PC
ParaFi Capital New York $361M AUM 39.32% 1-Year Est. Return
SFS
Solitude Financial Services Charlottesville, Virginia $361M AUM 21.75% 1-Year Est. Return
DFG
Demars Financial Group Spokane Valley, Washington $361M AUM 24.02% 1-Year Est. Return
PCM
Pamplona Capital Management New York $361M AUM 5.25% 1-Year Est. Return
FPM
Francisco Partners Management San Francisco, California $361M AUM 30.56% 1-Year Est. Return
LKIM
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Mass General Brigham's Q4 2025 Portfolio in Review

As of Q4 2025, Mass General Brigham held 7 positions worth $810M. Its ten largest holdings account for 100% of the portfolio.

Mass General Brigham deployed $797M of net new capital in Q4 2025, opening 7 new positions. Its largest new stake was iShares MSCI ACWI ETF: 4,613,955 shares worth $653M.

By sector, the portfolio is most concentrated in Miscellaneous at 81% of assets, followed by Industrials and Healthcare.

  • Mass General Brigham's largest Q4 2025 buy was iShares MSCI ACWI ETF: 4,613,955 shares worth $653M.
  • Mass General Brigham's ten largest holdings make up 100% of its $810M portfolio in Q4 2025.
  • Mass General Brigham opened 7 new positions and closed 0 in Q4 2025.

Based on Mass General Brigham's 13F filing for Q4 2025, filed 27 Jan 2026.