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JB

Julian Baker Baker Bros. Advisors

AUM $20B
1-Year Est. Return 154.41%
 

Julian Baker is co-managing member of Baker Bros. Advisors, a firm renowned for deep specialization in biotechnology and life sciences. The firm is known for concentrated positions, long holding periods, and scientific diligence that goes well beyond typical generalist research. Baker Bros. filings are closely watched by healthcare investors for signals in clinical-stage and commercial biotech.

This Fund
S&P 500
This Quarter Est. Return
+0.68%
1 Year Est. Return
+154.41%
3 Year Est. Return
+448.58%
5 Year Est. Return
+670.61%
10 Year Est. Return
+4,743.65%
AUM
$10.2B
AUM Growth
-$819M
Cap. Flow
-$1.84B
Cap. Flow %
-18.03%
Top 10 Hldgs %
83.92%
Holding
140
New
7
Increased
13
Reduced
18
Closed
7

Top Buys

Rank Stock Value
1
SGEN
Seagen Inc. Common Stock
SGEN
+$96.9M
2
ONC
BeOne Medicines Ltd
ONC
+$55.3M
3
AAAP
Advanced Accelerator Applications S.A.
AAAP
+$38.3M
4
AKAO
Achaogen Inc
AKAO
+$30.7M
5
AVXS
AveXis, Inc. Common Stock
AVXS
+$16.8M

Top Sells

Rank Stock Value
1
ABBV icon
AbbVie
ABBV
+$773M
2
EXEL icon
Exelixis
EXEL
+$27.8M
3
TGTX icon
TG Therapeutics
TGTX
+$15.5M
4
ARWR icon
Arrowhead Research
ARWR
+$13.6M
5
VTAE
VITAE PHARMACEUTICALS INC COMMON STOCK
VTAE
+$13.3M

Sector Composition

Rank Sector Weight
1 Healthcare 87.85%
2 Technology 0.01%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
SGEN
1
DELISTED
Seagen Inc. Common Stock
SGEN
$2.41B 23.65%
45,711,856
+1,611,562
+4% +$96.9M
INCY icon
2
Incyte
INCY
$25.9B
$2.36B 23.1%
23,499,087
+189
+0% +$18.4K
ALXN
3
DELISTED
Alexion Pharmaceuticals
ALXN
$801M 7.85%
6,543,295
– –
ACAD icon
4
Acadia Pharmaceuticals
ACAD
$5.08B
$745M 7.3%
25,819,768
– –
GHDX
5
DELISTED
Genomic Health, Inc.
GHDX
$405M 3.97%
13,770,302
– –
BMRN icon
6
BioMarin Pharmaceuticals
BMRN
$12.9B
$398M 3.9%
4,806,483
– –
DBVT
7
DBV Technologies
DBVT
$914M
$194M 1.9%
550,956
– –
NGNE icon
8
Neurogene
NGNE
$773M
$174M 1.71%
526,805
– –
ONC
9
BeOne Medicines Ltd
ONC
$42.4B
$112M 1.09%
3,673,175
+1,760,495
+92% +$55.3M
ABBV icon
10
AbbVie
ABBV
$468B
$106M 1.04%
1,685,994
-12,657,364
-88% -$773M
BCRX icon
11
BioCryst Pharmaceuticals
BCRX
$2.44B
$69.4M 0.68%
10,963,944
– –
AMRN
12
Amarin Corp
AMRN
$298M
$68.3M 0.67%
1,108,475
+76,951
+7% +$4.89M
BLCM
13
DELISTED
Bellicum Pharmaceuticals, Inc.
BLCM
$66.3M 0.65%
486,565
– –
ONCE
14
DELISTED
Spark Therapeutics, Inc. Common Stock
ONCE
$65.8M 0.64%
1,318,341
– –
ACOR
15
DELISTED
Acorda Therapeutics
ACOR
$62.1M 0.61%
27,515
-2,994
-10% -$7.12M
AKAO
16
DELISTED
Achaogen Inc
AKAO
$59.7M 0.58%
4,582,382
+4,482,382
+4,482% +$30.7M
AAAP
17
DELISTED
Advanced Accelerator Applications S.A.
AAAP
$58M 0.57%
2,167,137
+1,137,890
+111% +$38.3M
NVTA
18
DELISTED
Invitae Corporation
NVTA
$57.9M 0.57%
7,288,300
+733,333
+11% +$5.48M
CERS icon
19
Cerus
CERS
$566M
$56.8M 0.56%
13,053,275
– –
EXEL icon
20
Exelixis
EXEL
$13.4B
$44.8M 0.44%
3,003,569
-1,925,925
-39% -$27.8M
NBIX icon
21
Neurocrine Biosciences
NBIX
$15.5B
$34.7M 0.34%
895,422
– –
HRTX icon
22
Heron Therapeutics
HRTX
$60.4M
$31.2M 0.31%
2,383,569
-473,681
-17% -$7.43M
ARAV
23
DELISTED
Aravive, Inc. Common Stock
ARAV
$28.6M 0.28%
320,141
-35,567
-10% -$2.69M
FOMX
24
DELISTED
Foamix Pharmaceuticals Ltd. Ordinary Shares
FOMX
$27.4M 0.27%
2,466,702
– –
PGNX
25
DELISTED
Progenics Pharmaceuticals Inc
PGNX
$27.2M 0.27%
3,150,808
-500,000
-14% -$3.7M
1
2 3 4 5

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Julian Baker's Q4 2016 Portfolio in Review

As of Q4 2016, Julian Baker held 140 positions worth $10.2B, down 7.4% from $11B the previous quarter. Its ten largest holdings account for 84% of the portfolio.

Julian Baker withdrew a net $1.84B in Q4 2016, closing 7 positions and reducing 18 holdings. Its most notable exit was TG Therapeutics, an estimated $15.5M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 88% of assets, down from 88% a quarter earlier, followed by Technology.

Against the trend, Julian Baker opened a new position in AveXis, Inc. Common Stock worth $15M.

  • Julian Baker's largest Q4 2016 buy was AveXis, Inc. Common Stock: 315,300 shares worth $15M.
  • Julian Baker added most to Seagen Inc. Common Stock in Q4 2016, an estimated $96.9M increase.
  • Julian Baker's biggest Q4 2016 reduction was AbbVie, cutting an estimated $773M.
  • Julian Baker fully exited TG Therapeutics in Q4 2016, selling an estimated $15.5M.
  • Julian Baker's ten largest holdings make up 84% of its $10.2B portfolio in Q4 2016.
  • Julian Baker opened 7 new positions and closed 7 in Q4 2016.
  • Julian Baker's portfolio value fell 7.4% quarter-over-quarter to $10.2B.

Based on Baker Bros. Advisors's 13F filing for Q4 2016, filed 14 Feb 2017.