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JB

Julian Baker Baker Bros. Advisors

AUM $20B
1-Year Est. Return 154.41%
 

Julian Baker is co-managing member of Baker Bros. Advisors, a firm renowned for deep specialization in biotechnology and life sciences. The firm is known for concentrated positions, long holding periods, and scientific diligence that goes well beyond typical generalist research. Baker Bros. filings are closely watched by healthcare investors for signals in clinical-stage and commercial biotech.

This Fund
S&P 500
This Quarter Est. Return
+18.97%
1 Year Est. Return
+154.41%
3 Year Est. Return
+448.58%
5 Year Est. Return
+670.61%
10 Year Est. Return
+4,743.65%
AUM
$26.5B
AUM Growth
+$1.52B
Cap. Flow
-$117M
Cap. Flow %
-0.44%
Top 10 Hldgs %
84.24%
Holding
133
New
14
Increased
16
Reduced
60
Closed
7

Top Buys

Rank Stock Value
1
ABCL icon
AbCellera Biologics
ABCL
+$478M
2
NVTA
Invitae Corporation
NVTA
+$181M
3
KOD icon
Kodiak Sciences
KOD
+$170M
4
RARE icon
Ultragenyx Pharmaceutical
RARE
+$52.7M
5
OPT
Opthea Limited American Depositary Shares
OPT
+$41.8M

Top Sells

Rank Stock Value
1
ONC
BeOne Medicines Ltd
ONC
+$450M
2
MYOK
MyoKardia, Inc. Common Stock
MYOK
+$410M
3
EXAS
Exact Sciences
EXAS
+$188M
4
IMMU
Immunomedics Inc
IMMU
+$20.2M
5
AMRN
Amarin Corp
AMRN
+$19.4M

Sector Composition

Rank Sector Weight
1 Healthcare 99.87%
2 Financials 0%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
CPRX
126
DELISTED
Catalyst Pharmaceutical
CPRX
– –
-474,400
Closed -$1.41M
EXAS
127
DELISTED
Exact Sciences
EXAS
– –
-1,846,139
Closed -$188M
ARAV
128
DELISTED
Aravive, Inc. Common Stock
ARAV
– –
-75,854
Closed -$357K
UROV
129
DELISTED
Urovant Sciences Ltd.
UROV
– –
-978,505
Closed -$9.14M
MYOK
130
DELISTED
MyoKardia, Inc. Common Stock
MYOK
– –
-3,009,344
Closed -$410M
IMMU
131
DELISTED
Immunomedics Inc
IMMU
– –
-237,694
Closed -$20.2M
2 3 4 5
6

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Julian Baker's Q4 2020 Portfolio in Review

As of Q4 2020, Julian Baker held 133 positions worth $26.5B, up 6.1% from $25B the previous quarter. Its ten largest holdings account for 84% of the portfolio.

Julian Baker's Q4 2020 filing shows 14 new, 16 increased, 60 reduced and 7 closed positions. Its largest new stake was AbCellera Biologics: 10,450,180 shares worth $421M. The largest sale was BeOne Medicines Ltd, an estimated $450M.

By sector, the portfolio is most concentrated in Healthcare at 100% of assets, up from 100% a quarter earlier, followed by Financials.

  • Julian Baker's largest Q4 2020 buy was AbCellera Biologics: 10,450,180 shares worth $421M.
  • Julian Baker added most to Invitae Corporation in Q4 2020, an estimated $181M increase.
  • Julian Baker's biggest Q4 2020 reduction was BeOne Medicines Ltd, cutting an estimated $450M.
  • Julian Baker fully exited MyoKardia, Inc. Common Stock in Q4 2020, selling an estimated $410M.
  • Julian Baker's ten largest holdings make up 84% of its $26.5B portfolio in Q4 2020.
  • Julian Baker opened 14 new positions and closed 7 in Q4 2020.
  • Julian Baker's portfolio value rose 6.1% quarter-over-quarter to $26.5B.

Based on Baker Bros. Advisors's 13F filing for Q4 2020, filed 16 Feb 2021.