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JB

Julian Baker Baker Bros. Advisors

AUM $20B
1-Year Est. Return 154.41%
 

Julian Baker is co-managing member of Baker Bros. Advisors, a firm renowned for deep specialization in biotechnology and life sciences. The firm is known for concentrated positions, long holding periods, and scientific diligence that goes well beyond typical generalist research. Baker Bros. filings are closely watched by healthcare investors for signals in clinical-stage and commercial biotech.

This Fund
S&P 500
This Quarter Est. Return
-9.09%
1 Year Est. Return
+154.41%
3 Year Est. Return
+448.58%
5 Year Est. Return
+670.61%
10 Year Est. Return
+4,743.65%
AUM
$17.4B
AUM Growth
-$3.15B
Cap. Flow
+$225M
Cap. Flow %
1.29%
Top 10 Hldgs %
85.01%
Holding
121
New
2
Increased
15
Reduced
4
Closed
3

Top Buys

Rank Stock Value
1
INCY icon
Incyte
INCY
+$184M
2
KOD icon
Kodiak Sciences
KOD
+$48.8M
3
HZNP
Horizon Therapeutics Public Limited Company Ordinary Shares
HZNP
+$29.2M
4
TSVT
2seventy bio
TSVT
+$20.9M
5
REPL icon
Replimune Group
REPL
+$19.2M

Top Sells

Rank Stock Value
1
CCXI
ChemoCentryx, Inc.
CCXI
+$20.1M
2
LEGN icon
Legend Biotech
LEGN
+$19M
3
OPT
Opthea Limited American Depositary Shares
OPT
+$3.19M
4
ALBO
Albireo Pharma Inc
ALBO
+$2.43M
5
GMDA
Gamida Cell Ltd. Ordinary Shares
GMDA
+$1.55M

Sector Composition

Rank Sector Weight
1 Healthcare 99.5%
2 Financials 0.01%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
CABA icon
101
Cabaletta Bio
CABA
$531M
$1.34M 0.01%
662,063
– –
NEXI
102
DELISTED
NexImmune, Inc. Common Stock
NEXI
$1.24M 0.01%
11,765
– –
EPZM
103
DELISTED
Epizyme, Inc
EPZM
$1.15M 0.01%
+1,000,000
New +$1.63M
TARA icon
104
Protara Therapeutics
TARA
$228M
$1.02M 0.01%
199,671
– –
GTH
105
DELISTED
Genetron Holdings Limited ADS
GTH
$997K 0.01%
151,769
– –
CYPH
106
Cypherpunk Technologies Inc
CYPH
$153M
$979K 0.01%
55,971
– –
VINC
107
DELISTED
Vincerx Pharma, Inc. Common Stock
VINC
$966K 0.01%
12,069
– –
SERA icon
108
Sera Prognostics
SERA
$84.4M
$764K ﹤0.01%
201,562
– –
OYST
109
DELISTED
Oyster Point Pharma, Inc. Common Stock
OYST
$715K ﹤0.01%
61,424
– –
FHTX icon
110
Foghorn Therapeutics
FHTX
$420M
$686K ﹤0.01%
45,027
– –
BLCM
111
DELISTED
Bellicum Pharmaceuticals, Inc.
BLCM
$538K ﹤0.01%
249,123
– –
INZY
112
DELISTED
Inozyme Pharma
INZY
$438K ﹤0.01%
106,999
– –
PASG icon
113
Passage Bio
PASG
$14.3M
$363K ﹤0.01%
5,858
– –
LOGC
114
DELISTED
LogicBio Therapeutics, Inc. Common Stock
LOGC
$307K ﹤0.01%
451,478
– –
SRZNW
115
DELISTED
Surrozen Inc Warrant
SRZNW
$208K ﹤0.01%
833,333
– –
GMDA
116
DELISTED
Gamida Cell Ltd. Ordinary Shares
GMDA
– –
-610,626
Closed -$1.55M
ALBO
117
DELISTED
Albireo Pharma Inc
ALBO
– –
-104,521
Closed -$2.43M
EVFM
118
DELISTED
Evofem Biosciences, Inc. Common Stock
EVFM
– –
-179,807
Closed -$1.01M
1 2 3 4
5

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Julian Baker's Q1 2022 Portfolio in Review

As of Q1 2022, Julian Baker held 121 positions worth $17.4B, down 15% from $20.6B the previous quarter. Its ten largest holdings account for 85% of the portfolio.

Trading was light in Q1 2022: portfolio turnover was 4.1%. Julian Baker opened 2 new positions and exited 3, leaving the 121-position portfolio largely intact.

By sector, the portfolio is most concentrated in Healthcare at 100% of assets, up from 99% a quarter earlier, followed by Financials.

  • Julian Baker's largest Q1 2022 buy was Vera Therapeutics: 333,333 shares worth $7.83M.
  • Julian Baker added most to Incyte in Q1 2022, an estimated $184M increase.
  • Julian Baker's biggest Q1 2022 reduction was ChemoCentryx, Inc., cutting an estimated $20.1M.
  • Julian Baker fully exited Albireo Pharma Inc in Q1 2022, selling an estimated $2.43M.
  • Julian Baker's ten largest holdings make up 85% of its $17.4B portfolio in Q1 2022.
  • Julian Baker opened 2 new positions and closed 3 in Q1 2022.
  • Julian Baker's portfolio value fell 15% quarter-over-quarter to $17.4B.

Based on Baker Bros. Advisors's 13F filing for Q1 2022, filed 16 May 2022.