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JB

Julian Baker Baker Bros. Advisors

AUM $20B
1-Year Est. Return 154.41%
 

Julian Baker is co-managing member of Baker Bros. Advisors, a firm renowned for deep specialization in biotechnology and life sciences. The firm is known for concentrated positions, long holding periods, and scientific diligence that goes well beyond typical generalist research. Baker Bros. filings are closely watched by healthcare investors for signals in clinical-stage and commercial biotech.

This Fund
S&P 500
This Quarter Est. Return
+0.68%
1 Year Est. Return
+154.41%
3 Year Est. Return
+448.58%
5 Year Est. Return
+670.61%
10 Year Est. Return
+4,743.65%
AUM
$10.2B
AUM Growth
-$819M
Cap. Flow
-$1.84B
Cap. Flow %
-18.03%
Top 10 Hldgs %
83.92%
Holding
140
New
7
Increased
13
Reduced
18
Closed
7

Top Buys

Rank Stock Value
1
SGEN
Seagen Inc. Common Stock
SGEN
+$96.9M
2
ONC
BeOne Medicines Ltd
ONC
+$55.3M
3
AAAP
Advanced Accelerator Applications S.A.
AAAP
+$38.3M
4
AKAO
Achaogen Inc
AKAO
+$30.7M
5
AVXS
AveXis, Inc. Common Stock
AVXS
+$16.8M

Top Sells

Rank Stock Value
1
ABBV icon
AbbVie
ABBV
+$773M
2
EXEL icon
Exelixis
EXEL
+$27.8M
3
TGTX icon
TG Therapeutics
TGTX
+$15.5M
4
ARWR icon
Arrowhead Research
ARWR
+$13.6M
5
VTAE
VITAE PHARMACEUTICALS INC COMMON STOCK
VTAE
+$13.3M

Sector Composition

Rank Sector Weight
1 Healthcare 87.85%
2 Technology 0.01%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
MDGL icon
101
Madrigal Pharmaceuticals
MDGL
$11.9B
$861K 0.01%
57,762
– –
CLLS
102
Cellectis
CLLS
$342M
$848K 0.01%
50,000
– –
TENX icon
103
Tenax Therapeutics
TENX
$65.5M
$819K 0.01%
13
– –
IMDZ
104
DELISTED
Immune Design Corp.
IMDZ
$819K 0.01%
148,937
– –
INFI
105
DELISTED
Infinity Pharmaceuticals, Inc.
INFI
$784K 0.01%
580,400
– –
ALDX icon
106
Aldeyra Therapeutics
ALDX
$91.7M
$760K 0.01%
142,000
– –
TARA icon
107
Protara Therapeutics
TARA
$228M
$740K 0.01%
9,735
+2,270
+30% +$718K
XLRN
108
DELISTED
Acceleron Pharma
XLRN
$734K 0.01%
28,765
– –
AFMD
109
DELISTED
Affimed
AFMD
$720K 0.01%
40,000
– –
CBAY
110
DELISTED
Cymabay Therapeutics
CBAY
$535K 0.01%
+309,268
New +$546K
CMRX
111
DELISTED
Chimerix, Inc.
CMRX
$530K 0.01%
115,216
– –
ABUS icon
112
Arbutus Biopharma
ABUS
$1.03B
$442K ﹤0.01%
180,582
– –
ALNY icon
113
Alnylam Pharmaceuticals
ALNY
$31.6B
$425K ﹤0.01%
11,340
– –
ADAP
114
DELISTED
Adaptimmune Therapeutics
ADAP
$405K ﹤0.01%
100,000
– –
FMI
115
DELISTED
Foundation Medicine, Inc.
FMI
$370K ﹤0.01%
20,892
– –
BDSI
116
DELISTED
BioDelivery Sciences International, Inc.
BDSI
$368K ﹤0.01%
210,021
– –
CCXI
117
DELISTED
ChemoCentryx, Inc.
CCXI
$363K ﹤0.01%
49,064
– –
APTO
118
DELISTED
Aptose Biosciences, Inc.
APTO
$359K ﹤0.01%
574
-324
-36% -$202K
WINT
119
DELISTED
Windtree Therapeutics Inc
WINT
$319K ﹤0.01%
254,973
– –
SRRA
120
DELISTED
Sierra Oncology, Inc. Common Stock
SRRA
$298K ﹤0.01%
5,000
– –
DVAX
121
DELISTED
Dynavax Technologies
DVAX
$296K ﹤0.01%
75,000
– –
LJPC
122
DELISTED
La Jolla Pharmaceutical Company
LJPC
$241K ﹤0.01%
13,746
– –
BGMSP
123
DELISTED
Bio Green Med Solution Inc Preferred Stock
BGMSP
$82K ﹤0.01%
13,253
– –
BTX.WS
124
DELISTED
BioTime Inc Warrants (Expiring October 1, 2018)
BTX.WS
$14K ﹤0.01%
20,084
– –
ARWR icon
125
Arrowhead Research
ARWR
$12.3B
– –
-1,856,967
Closed -$13.6M
2 3 4
5
6

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Julian Baker's Q4 2016 Portfolio in Review

As of Q4 2016, Julian Baker held 140 positions worth $10.2B, down 7.4% from $11B the previous quarter. Its ten largest holdings account for 84% of the portfolio.

Julian Baker withdrew a net $1.84B in Q4 2016, closing 7 positions and reducing 18 holdings. Its most notable exit was TG Therapeutics, an estimated $15.5M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 88% of assets, down from 88% a quarter earlier, followed by Technology.

Against the trend, Julian Baker opened a new position in AveXis, Inc. Common Stock worth $15M.

  • Julian Baker's largest Q4 2016 buy was AveXis, Inc. Common Stock: 315,300 shares worth $15M.
  • Julian Baker added most to Seagen Inc. Common Stock in Q4 2016, an estimated $96.9M increase.
  • Julian Baker's biggest Q4 2016 reduction was AbbVie, cutting an estimated $773M.
  • Julian Baker fully exited TG Therapeutics in Q4 2016, selling an estimated $15.5M.
  • Julian Baker's ten largest holdings make up 84% of its $10.2B portfolio in Q4 2016.
  • Julian Baker opened 7 new positions and closed 7 in Q4 2016.
  • Julian Baker's portfolio value fell 7.4% quarter-over-quarter to $10.2B.

Based on Baker Bros. Advisors's 13F filing for Q4 2016, filed 14 Feb 2017.