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JB

Julian Baker Baker Bros. Advisors

AUM $20B
1-Year Est. Return 154.41%
 

Julian Baker is co-managing member of Baker Bros. Advisors, a firm renowned for deep specialization in biotechnology and life sciences. The firm is known for concentrated positions, long holding periods, and scientific diligence that goes well beyond typical generalist research. Baker Bros. filings are closely watched by healthcare investors for signals in clinical-stage and commercial biotech.

This Fund
S&P 500
This Quarter Est. Return
-21.22%
1 Year Est. Return
+154.41%
3 Year Est. Return
+448.58%
5 Year Est. Return
+670.61%
10 Year Est. Return
+4,743.65%
AUM
$9.48B
AUM Growth
-$2.59B
Cap. Flow
-$1.26B
Cap. Flow %
-13.32%
Top 10 Hldgs %
78.76%
Holding
139
New
5
Increased
29
Reduced
8
Closed
5

Top Buys

Rank Stock Value
1
INCY icon
Incyte
INCY
+$300M
2
SGEN
Seagen Inc. Common Stock
SGEN
+$200M
3
ACAD icon
Acadia Pharmaceuticals
ACAD
+$81.4M
4
ANAC
ANACOR PHARMACEUTICALS INC COM
ANAC
+$68.2M
5
BMRN icon
BioMarin Pharmaceuticals
BMRN
+$56.3M

Top Sells

Rank Stock Value
1
DYAX
DYAX CORPORATION
DYAX
+$313M
2
GILD icon
Gilead Sciences
GILD
+$25.3M
3
MDVN
MEDIVATION, INC.
MDVN
+$12M
4
CPRX
Catalyst Pharmaceutical
CPRX
+$4.31M
5
IOVA icon
Iovance Biotherapeutics
IOVA
+$4.11M

Sector Composition

Rank Sector Weight
1 Healthcare 82.24%
2 Technology 0%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
PTN
101
Palatin Technologies
PTN
$17.2M
$1.11M 0.01%
1,640
– –
GWPH
102
DELISTED
GW Pharmaceuticals Plc American Depositary Shares
GWPH
$1.08M 0.01%
+15,000
New +$823K
TENX icon
103
Tenax Therapeutics
TENX
$65.5M
$861K 0.01%
13
– –
ADAP
104
DELISTED
Adaptimmune Therapeutics
ADAP
$813K 0.01%
100,000
– –
FPRX
105
DELISTED
Five Prime Therapeutics, Inc.
FPRX
$782K 0.01%
19,247
– –
XLRN
106
DELISTED
Acceleron Pharma
XLRN
$759K 0.01%
28,765
– –
ABUS icon
107
Arbutus Biopharma
ABUS
$1.03B
$746K 0.01%
180,582
– –
ALNY icon
108
Alnylam Pharmaceuticals
ALNY
$31.6B
$712K 0.01%
11,340
– –
BDSI
109
DELISTED
BioDelivery Sciences International, Inc.
BDSI
$678K 0.01%
210,021
– –
ALDX icon
110
Aldeyra Therapeutics
ALDX
$91.7M
$595K 0.01%
142,000
– –
CMRX
111
DELISTED
Chimerix, Inc.
CMRX
$589K 0.01%
115,216
– –
AIXC
112
AIxCrypto Holdings Inc
AIXC
$22.7M
$452K ﹤0.01%
3
– –
WINT
113
DELISTED
Windtree Therapeutics Inc
WINT
$426K ﹤0.01%
254,973
-2
-0% -$4
FMI
114
DELISTED
Foundation Medicine, Inc.
FMI
$380K ﹤0.01%
20,892
– –
LJPC
115
DELISTED
La Jolla Pharmaceutical Company
LJPC
$287K ﹤0.01%
13,746
– –
AKAO
116
DELISTED
Achaogen Inc
AKAO
$276K ﹤0.01%
100,000
– –
CCXI
117
DELISTED
ChemoCentryx, Inc.
CCXI
$122K ﹤0.01%
49,064
– –
APTO
118
DELISTED
Aptose Biosciences, Inc.
APTO
$100K ﹤0.01%
74
– –
BGMSP
119
DELISTED
Bio Green Med Solution Inc Preferred Stock
BGMSP
$76K ﹤0.01%
13,253
– –
BTX.WS
120
DELISTED
BioTime Inc Warrants (Expiring October 1, 2018)
BTX.WS
$12K ﹤0.01%
20,084
– –
GILD icon
121
Gilead Sciences
GILD
$181B
– –
-249,995
Closed -$25.3M
MRNS
122
DELISTED
Marinus Pharmaceuticals, Inc
MRNS
– –
-50,000
Closed -$1.53M
NBSE
123
DELISTED
NeuBase Therapeutics, Inc. Common Stock
NBSE
– –
-926
Closed -$2.27M
FLXN
124
DELISTED
Flexion Therapeutics, Inc.
FLXN
– –
-146,642
Closed -$2.83M
DYAX
125
DELISTED
DYAX CORPORATION
DYAX
– –
-8,310,017
Closed -$313M
1 2 3 4
5

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Julian Baker's Q1 2016 Portfolio in Review

As of Q1 2016, Julian Baker held 139 positions worth $9.48B, down 21% from $12.1B the previous quarter. Its ten largest holdings account for 79% of the portfolio.

Julian Baker withdrew a net $1.26B in Q1 2016, closing 5 positions and reducing 8 holdings. Its most notable exit was DYAX CORPORATION, an estimated $313M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 82% of assets, up from 79% a quarter earlier, followed by Technology.

Against the trend, Julian Baker opened a new position in BeOne Medicines Ltd worth $56.1M.

  • Julian Baker's largest Q1 2016 buy was BeOne Medicines Ltd: 1,912,680 shares worth $56.1M.
  • Julian Baker added most to Incyte in Q1 2016, an estimated $300M increase.
  • Julian Baker's biggest Q1 2016 reduction was MEDIVATION, INC., cutting an estimated $12M.
  • Julian Baker fully exited DYAX CORPORATION in Q1 2016, selling an estimated $313M.
  • Julian Baker's ten largest holdings make up 79% of its $9.48B portfolio in Q1 2016.
  • Julian Baker opened 5 new positions and closed 5 in Q1 2016.
  • Julian Baker's portfolio value fell 21% quarter-over-quarter to $9.48B.

Based on Baker Bros. Advisors's 13F filing for Q1 2016, filed 16 May 2016.