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JB

Julian Baker Baker Bros. Advisors

AUM $20B
1-Year Est. Return 154.41%
 

Julian Baker is co-managing member of Baker Bros. Advisors, a firm renowned for deep specialization in biotechnology and life sciences. The firm is known for concentrated positions, long holding periods, and scientific diligence that goes well beyond typical generalist research. Baker Bros. filings are closely watched by healthcare investors for signals in clinical-stage and commercial biotech.

This Fund
S&P 500
This Quarter Est. Return
+13.19%
1 Year Est. Return
+154.41%
3 Year Est. Return
+448.58%
5 Year Est. Return
+670.61%
10 Year Est. Return
+4,743.65%
AUM
$12.1B
AUM Growth
+$1.25B
Cap. Flow
-$1.53B
Cap. Flow %
-12.71%
Top 10 Hldgs %
75.84%
Holding
141
New
6
Increased
25
Reduced
5
Closed
8

Top Buys

Rank Stock Value
1
ACOR
Acorda Therapeutics
ACOR
+$90.4M
2
SGEN
Seagen Inc. Common Stock
SGEN
+$52.6M
3
DYAX
DYAX CORPORATION
DYAX
+$24.1M
4
ALKS icon
Alkermes
ALKS
+$17.5M
5
AAAP
Advanced Accelerator Applications S.A.
AAAP
+$15.8M

Top Sells

Rank Stock Value
1
CLVS
Clovis Oncology, Inc.
CLVS
+$18.6M
2
XNPT
XENOPORT, INC.
XNPT
+$17M
3
ALDR
Alder Biopharmaceuticals
ALDR
+$16.8M
4
RPRX
Repros Therapeutics Inc.
RPRX
+$14.5M
5
LRMR icon
Larimar Therapeutics
LRMR
+$12.5M

Sector Composition

Rank Sector Weight
1 Healthcare 78.52%
2 Technology 0.01%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
XLRN
101
DELISTED
Acceleron Pharma
XLRN
$1.4M 0.01%
28,765
– –
TENX icon
102
Tenax Therapeutics
TENX
$65.5M
$1.38M 0.01%
13
– –
PTN
103
Palatin Technologies
PTN
$17.2M
$1.36M 0.01%
1,640
– –
ADAP
104
DELISTED
Adaptimmune Therapeutics
ADAP
$1.21M 0.01%
100,000
– –
ALNY icon
105
Alnylam Pharmaceuticals
ALNY
$31.6B
$1.07M 0.01%
11,340
– –
CMRX
106
DELISTED
Chimerix, Inc.
CMRX
$1.03M 0.01%
115,216
– –
BDSI
107
DELISTED
BioDelivery Sciences International, Inc.
BDSI
$1.01M 0.01%
210,021
– –
ALDX icon
108
Aldeyra Therapeutics
ALDX
$91.7M
$963K 0.01%
142,000
– –
ABUS icon
109
Arbutus Biopharma
ABUS
$1.03B
$804K 0.01%
180,582
– –
FPRX
110
DELISTED
Five Prime Therapeutics, Inc.
FPRX
$799K 0.01%
19,247
– –
WINT
111
DELISTED
Windtree Therapeutics Inc
WINT
$764K 0.01%
254,975
– –
AIXC
112
AIxCrypto Holdings Inc
AIXC
$22.7M
$680K 0.01%
3
– –
AKAO
113
DELISTED
Achaogen Inc
AKAO
$574K ﹤0.01%
100,000
– –
QURE icon
114
uniQure
QURE
$3.36B
$496K ﹤0.01%
30,000
– –
FMI
115
DELISTED
Foundation Medicine, Inc.
FMI
$440K ﹤0.01%
20,892
– –
CCXI
116
DELISTED
ChemoCentryx, Inc.
CCXI
$397K ﹤0.01%
49,064
– –
LJPC
117
DELISTED
La Jolla Pharmaceutical Company
LJPC
$371K ﹤0.01%
13,746
-398,262
-97% -$10.9M
APTO
118
DELISTED
Aptose Biosciences, Inc.
APTO
$84K ﹤0.01%
74
– –
BGMSP
119
DELISTED
Bio Green Med Solution Inc Preferred Stock
BGMSP
$52K ﹤0.01%
+13,253
New +$62.2K
BTX.WS
120
DELISTED
BioTime Inc Warrants (Expiring October 1, 2018)
BTX.WS
$24K ﹤0.01%
20,084
– –
LRMR icon
121
Larimar Therapeutics
LRMR
$434M
– –
-32,529
Closed -$12.5M
MTEM
122
DELISTED
Molecular Templates, Inc.
MTEM
– –
-17,730
Closed -$11.9M
CLVS
123
DELISTED
Clovis Oncology, Inc.
CLVS
– –
-202,630
Closed -$18.6M
BLPH
124
DELISTED
Bellerophon Therapeutics, Inc.
BLPH
– –
-23,529
Closed -$1.83M
ALDR
125
DELISTED
Alder Biopharmaceuticals
ALDR
– –
-513,439
Closed -$16.8M
2 3 4
5
6

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Julian Baker's Q4 2015 Portfolio in Review

As of Q4 2015, Julian Baker held 141 positions worth $12.1B, up 12% from $10.8B the previous quarter. Its ten largest holdings account for 76% of the portfolio.

Julian Baker withdrew a net $1.53B in Q4 2015, closing 8 positions and reducing 5 holdings. Its most notable exit was Clovis Oncology, Inc., an estimated $18.6M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 79% of assets, up from 78% a quarter earlier, followed by Technology.

Against the trend, Julian Baker opened a new position in Alkermes worth $19.9M.

  • Julian Baker's largest Q4 2015 buy was Alkermes: 250,251 shares worth $19.9M.
  • Julian Baker added most to Acorda Therapeutics in Q4 2015, an estimated $90.4M increase.
  • Julian Baker's biggest Q4 2015 reduction was XENOPORT, INC., cutting an estimated $17M.
  • Julian Baker fully exited Clovis Oncology, Inc. in Q4 2015, selling an estimated $18.6M.
  • Julian Baker's ten largest holdings make up 76% of its $12.1B portfolio in Q4 2015.
  • Julian Baker opened 6 new positions and closed 8 in Q4 2015.
  • Julian Baker's portfolio value rose 12% quarter-over-quarter to $12.1B.

Based on Baker Bros. Advisors's 13F filing for Q4 2015, filed 16 Feb 2016.