We are live on ! Find out more
JB

Julian Baker Baker Bros. Advisors

AUM $20B
1-Year Est. Return 154.41%
 

Julian Baker is co-managing member of Baker Bros. Advisors, a firm renowned for deep specialization in biotechnology and life sciences. The firm is known for concentrated positions, long holding periods, and scientific diligence that goes well beyond typical generalist research. Baker Bros. filings are closely watched by healthcare investors for signals in clinical-stage and commercial biotech.

This Fund
S&P 500
This Quarter Est. Return
-9.09%
1 Year Est. Return
+154.41%
3 Year Est. Return
+448.58%
5 Year Est. Return
+670.61%
10 Year Est. Return
+4,743.65%
AUM
$17.4B
AUM Growth
-$3.15B
Cap. Flow
+$225M
Cap. Flow %
1.29%
Top 10 Hldgs %
85.01%
Holding
121
New
2
Increased
15
Reduced
4
Closed
3

Top Buys

Rank Stock Value
1
INCY icon
Incyte
INCY
+$184M
2
KOD icon
Kodiak Sciences
KOD
+$48.8M
3
HZNP
Horizon Therapeutics Public Limited Company Ordinary Shares
HZNP
+$29.2M
4
TSVT
2seventy bio
TSVT
+$20.9M
5
REPL icon
Replimune Group
REPL
+$19.2M

Top Sells

Rank Stock Value
1
CCXI
ChemoCentryx, Inc.
CCXI
+$20.1M
2
LEGN icon
Legend Biotech
LEGN
+$19M
3
OPT
Opthea Limited American Depositary Shares
OPT
+$3.19M
4
ALBO
Albireo Pharma Inc
ALBO
+$2.43M
5
GMDA
Gamida Cell Ltd. Ordinary Shares
GMDA
+$1.55M

Sector Composition

Rank Sector Weight
1 Healthcare 99.5%
2 Financials 0.01%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
CBAY
76
DELISTED
Cymabay Therapeutics
CBAY
$6.75M 0.04%
2,170,464
– –
ALT icon
77
Altimmune
ALT
$605M
$6.53M 0.04%
1,072,038
– –
HRMY icon
78
Harmony Biosciences
HRMY
$2.22B
$6.01M 0.03%
123,600
– –
TNGX icon
79
Tango Therapeutics
TNGX
$4.03B
$5.68M 0.03%
750,000
– –
RVMD icon
80
Revolution Medicines
RVMD
$44.9B
$5.67M 0.03%
222,222
– –
HOOK
81
DELISTED
HOOKIPA Pharma
HOOK
$5.47M 0.03%
240,048
+170,000
+243% +$3.05M
EWTX icon
82
Edgewise Therapeutics
EWTX
$4.8B
$4.85M 0.03%
500,000
– –
ITOS
83
DELISTED
iTeos Therapeutics
ITOS
$4.84M 0.03%
150,346
– –
ALGS icon
84
Aligos Therapeutics
ALGS
$41.7M
$4.46M 0.03%
83,056
– –
NGM
85
DELISTED
NGM Biopharmaceuticals, Inc. Common Stock
NGM
$4.45M 0.03%
291,801
– –
KURA icon
86
Kura Oncology
KURA
$1.06B
$4.41M 0.03%
274,458
-29,700
-10% -$429K
BCAB icon
87
BioAtla
BCAB
$5.3M
$4.13M 0.02%
16,500
– –
ALLK
88
DELISTED
Allakos
ALLK
$4.01M 0.02%
703,050
– –
TCRX icon
89
TScan Therapeutics
TCRX
$52.8M
$3.99M 0.02%
1,425,000
– –
MGNX icon
90
MacroGenics
MGNX
$261M
$3.9M 0.02%
442,579
– –
NVAX icon
91
Novavax
NVAX
$1.47B
$3.55M 0.02%
48,168
– –
ALEC icon
92
Alector
ALEC
$264M
$3.41M 0.02%
239,228
– –
ATYR
93
aTyr Pharma
ATYR
$49.2M
$3.34M 0.02%
625,000
– –
CYT
94
DELISTED
Cyteir Therapeutics, Inc. Common Stock
CYT
$3.06M 0.02%
812,640
– –
DNLI icon
95
Denali Therapeutics
DNLI
$3.98B
$2.85M 0.02%
88,738
– –
KZR
96
DELISTED
Kezar Life Sciences
KZR
$2.32M 0.01%
13,968
– –
TCRR
97
DELISTED
TCR2 Therapeutics Inc. Common Stock
TCRR
$2.08M 0.01%
753,064
– –
BNR
98
Burning Rock Biotech
BNR
$103M
$1.94M 0.01%
20,913
– –
SNDX icon
99
Syndax Pharmaceuticals
SNDX
$1.75B
$1.92M 0.01%
110,729
– –
AKRO
100
DELISTED
Akero Therapeutics
AKRO
$1.68M 0.01%
118,378
– –
1 2 3
4
5

Similar funds

ASRS
Arizona State Retirement System Phoenix, Arizona $19.9B AUM 44.71% 1-Year Est. Return
FWIA
Fort Washington Investment Advisors Cincinnati, Ohio $19.9B AUM 22.19% 1-Year Est. Return
CWP
Capital Wealth Planning Naples, Florida $20B AUM 25.34% 1-Year Est. Return
SFA
Sequoia Financial Advisors Akron, Ohio $20.1B AUM 24.77% 1-Year Est. Return
MGP
M&G plc London, United Kingdom $20.1B AUM 16.62% 1-Year Est. Return
JAM
Jupiter Asset Management London, United Kingdom $20.2B AUM 29.18% 1-Year Est. Return
Verition Fund Management
Verition Fund Management Greenwich, Connecticut $19.7B AUM 39.39% 1-Year Est. Return
Select Equity Group
Select Equity Group New York $20.2B AUM 17.52% 1-Year Est. Return

Julian Baker's Q1 2022 Portfolio in Review

As of Q1 2022, Julian Baker held 121 positions worth $17.4B, down 15% from $20.6B the previous quarter. Its ten largest holdings account for 85% of the portfolio.

Trading was light in Q1 2022: portfolio turnover was 4.1%. Julian Baker opened 2 new positions and exited 3, leaving the 121-position portfolio largely intact.

By sector, the portfolio is most concentrated in Healthcare at 100% of assets, up from 99% a quarter earlier, followed by Financials.

  • Julian Baker's largest Q1 2022 buy was Vera Therapeutics: 333,333 shares worth $7.83M.
  • Julian Baker added most to Incyte in Q1 2022, an estimated $184M increase.
  • Julian Baker's biggest Q1 2022 reduction was ChemoCentryx, Inc., cutting an estimated $20.1M.
  • Julian Baker fully exited Albireo Pharma Inc in Q1 2022, selling an estimated $2.43M.
  • Julian Baker's ten largest holdings make up 85% of its $17.4B portfolio in Q1 2022.
  • Julian Baker opened 2 new positions and closed 3 in Q1 2022.
  • Julian Baker's portfolio value fell 15% quarter-over-quarter to $17.4B.

Based on Baker Bros. Advisors's 13F filing for Q1 2022, filed 16 May 2022.