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JB

Julian Baker Baker Bros. Advisors

AUM $20B
1-Year Est. Return 154.41%
 

Julian Baker is co-managing member of Baker Bros. Advisors, a firm renowned for deep specialization in biotechnology and life sciences. The firm is known for concentrated positions, long holding periods, and scientific diligence that goes well beyond typical generalist research. Baker Bros. filings are closely watched by healthcare investors for signals in clinical-stage and commercial biotech.

This Fund
S&P 500
This Quarter Est. Return
+4.02%
1 Year Est. Return
+154.41%
3 Year Est. Return
+448.58%
5 Year Est. Return
+670.61%
10 Year Est. Return
+4,743.65%
AUM
$14.7B
AUM Growth
-$14.5M
Cap. Flow
+$16.2M
Cap. Flow %
0.11%
Top 10 Hldgs %
85.95%
Holding
111
New
8
Increased
15
Reduced
6
Closed
2

Top Buys

Rank Stock Value
1
NVTA
Invitae Corporation
NVTA
+$115M
2
IGMS
IGM Biosciences
IGMS
+$63.5M
3
ACAD icon
Acadia Pharmaceuticals
ACAD
+$47.4M
4
MYOK
MyoKardia, Inc. Common Stock
MYOK
+$26.6M
5
URGN icon
UroGen Pharma
URGN
+$24.4M

Top Sells

Rank Stock Value
1
ARRY
Array Biopharma Inc
ARRY
+$132M
2
MRTX
Mirati Therapeutics, Inc. Common Stock
MRTX
+$113M
3
CPRX
Catalyst Pharmaceutical
CPRX
+$6.49M
4
BCRX icon
BioCryst Pharmaceuticals
BCRX
+$5.15M
5
PRNB
Principia Biopharma Inc. Common Stock
PRNB
+$4.91M

Sector Composition

Rank Sector Weight
1 Healthcare 99.6%
2 Financials 0.01%
3 Technology 0%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
ABEO icon
76
Abeona Therapeutics
ABEO
$348M
$2.91M 0.02%
51,529
– –
GTHX
77
DELISTED
G1 Therapeutics, Inc. Common Stock
GTHX
$2.9M 0.02%
127,236
– –
DOVA
78
DELISTED
Dova Pharmaceuticals, Inc. Common Stock
DOVA
$2.86M 0.02%
102,205
+2,800
+3% +$45.4K
BLCM
79
DELISTED
Bellicum Pharmaceuticals, Inc.
BLCM
$2.81M 0.02%
267,782
– –
YMAB
80
DELISTED
Y-mAbs Therapeutics
YMAB
$2.68M 0.02%
102,800
– –
CRNX icon
81
Crinetics Pharmaceuticals
CRNX
$8.99B
$2.63M 0.02%
175,000
+42,015
+32% +$817K
CYCN icon
82
Cyclerion Therapeutics
CYCN
$18.2M
$2.46M 0.02%
10,129
– –
FSTX
83
DELISTED
F-star Therapeutics, Inc. Common Stock
FSTX
$2.11M 0.01%
153,286
– –
AUTL
84
Autolus Therapeutics
AUTL
$641M
$1.95M 0.01%
156,773
– –
IDYA icon
85
IDEAYA Biosciences
IDYA
$3.83B
$1.8M 0.01%
200,000
– –
NTLA icon
86
Intellia Therapeutics
NTLA
$1.8B
$1.72M 0.01%
128,538
– –
MTEM
87
DELISTED
Molecular Templates, Inc.
MTEM
$1.68M 0.01%
16,949
– –
FTSV
88
DELISTED
Forty Seven, Inc. Common Stock
FTSV
$1.6M 0.01%
250,000
– –
FOMX
89
DELISTED
Foamix Pharmaceuticals Ltd. Ordinary Shares
FOMX
$1.51M 0.01%
498,189
– –
CTMX icon
90
CytomX Therapeutics
CTMX
$715M
$1.44M 0.01%
194,377
– –
CCXI
91
DELISTED
ChemoCentryx, Inc.
CCXI
$1.4M 0.01%
207,029
– –
FLGT icon
92
Fulgent Genetics
FLGT
$548M
$1.3M 0.01%
125,000
– –
MTNB icon
93
Matinas BioPharma
MTNB
$2.92M
$1.25M 0.01%
+39,699
New +$1.43M
CYPH
94
Cypherpunk Technologies Inc
CYPH
$153M
$1.15M 0.01%
+97,845
New +$1.69M
RCUS icon
95
Arcus Biosciences
RCUS
$3.86B
$1.11M 0.01%
121,534
– –
GLMD icon
96
Galmed Pharmaceuticals
GLMD
$4.48M
$1.03M 0.01%
150
– –
ADMS
97
DELISTED
Adamas Pharmaceuticals
ADMS
$883K 0.01%
172,630
– –
CNST
98
DELISTED
Constellation Pharmaceuticals, Inc.
CNST
$861K 0.01%
133,333
– –
SRRA
99
DELISTED
Sierra Oncology, Inc. Common Stock
SRRA
$781K 0.01%
50,000
– –
INFI
100
DELISTED
Infinity Pharmaceuticals, Inc.
INFI
$598K ﹤0.01%
580,400
– –
1 2 3
4
5

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Julian Baker's Q3 2019 Portfolio in Review

As of Q3 2019, Julian Baker held 111 positions worth $14.7B, down 0.1% from $14.7B the previous quarter. Its ten largest holdings account for 86% of the portfolio.

Julian Baker's Q3 2019 filing shows 8 new, 15 increased, 6 reduced and 2 closed positions. Its largest new stake was IGM Biosciences: 3,144,000 shares worth $55.8M. The largest sale was Array Biopharma Inc, an estimated $132M.

By sector, the portfolio is most concentrated in Healthcare at 100% of assets, down from 100% a quarter earlier, followed by Financials and Technology.

  • Julian Baker's largest Q3 2019 buy was IGM Biosciences: 3,144,000 shares worth $55.8M.
  • Julian Baker added most to Invitae Corporation in Q3 2019, an estimated $115M increase.
  • Julian Baker's biggest Q3 2019 reduction was Mirati Therapeutics, Inc. Common Stock, cutting an estimated $113M.
  • Julian Baker fully exited Array Biopharma Inc in Q3 2019, selling an estimated $132M.
  • Julian Baker's ten largest holdings make up 86% of its $14.7B portfolio in Q3 2019.
  • Julian Baker opened 8 new positions and closed 2 in Q3 2019.
  • Julian Baker's portfolio value fell 0.1% quarter-over-quarter to $14.7B.

Based on Baker Bros. Advisors's 13F filing for Q3 2019, filed 14 Nov 2019.