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JB

Julian Baker Baker Bros. Advisors

AUM $20B
1-Year Est. Return 154.41%
 

Julian Baker is co-managing member of Baker Bros. Advisors, a firm renowned for deep specialization in biotechnology and life sciences. The firm is known for concentrated positions, long holding periods, and scientific diligence that goes well beyond typical generalist research. Baker Bros. filings are closely watched by healthcare investors for signals in clinical-stage and commercial biotech.

This Fund
S&P 500
This Quarter Est. Return
+12.82%
1 Year Est. Return
+154.41%
3 Year Est. Return
+448.58%
5 Year Est. Return
+670.61%
10 Year Est. Return
+4,743.65%
AUM
$13.3B
AUM Growth
+$1.51B
Cap. Flow
+$1.01B
Cap. Flow %
7.58%
Top 10 Hldgs %
83.56%
Holding
124
New
10
Increased
16
Reduced
22
Closed
5

Top Buys

Rank Stock Value
1
ONC
BeOne Medicines Ltd
ONC
+$1.09B
2
MDGL icon
Madrigal Pharmaceuticals
MDGL
+$97.2M
3
SGEN
Seagen Inc. Common Stock
SGEN
+$84.2M
4
KNSA icon
Kiniksa Pharmaceuticals
KNSA
+$54.3M
5
TCDA
Tricida, Inc. Common Stock
TCDA
+$44.7M

Top Sells

Rank Stock Value
1
AVXS
AveXis, Inc. Common Stock
AVXS
+$144M
2
ABLX
Ablynx NV
ABLX
+$119M
3
NKTR icon
Nektar Therapeutics
NKTR
+$29.3M
4
EXEL icon
Exelixis
EXEL
+$13.4M
5
PGNX
Progenics Pharmaceuticals Inc
PGNX
+$10.1M

Sector Composition

Rank Sector Weight
1 Healthcare 99.23%
2 Technology 0.01%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
FSTX
76
DELISTED
F-star Therapeutics, Inc. Common Stock
FSTX
$4.42M 0.03%
93,286
– –
APLS
77
DELISTED
Apellis Pharmaceuticals
APLS
$4.31M 0.03%
+196,078
New +$4.5M
NTRA icon
78
Natera
NTRA
$47.9B
$4.3M 0.03%
228,676
– –
ALKS icon
79
Alkermes
ALKS
$8.11B
$4.13M 0.03%
100,251
– –
AERI
80
DELISTED
Aerie Pharmaceuticals
AERI
$4.06M 0.03%
60,155
-155,500
-72% -$8.7M
FTSV
81
DELISTED
Forty Seven, Inc. Common Stock
FTSV
$4M 0.03%
+250,000
New +$3.88M
TTPH
82
DELISTED
Tetraphase Pharmaceuticals, Inc.
TTPH
$3.34M 0.03%
46,750
– –
NBRV
83
DELISTED
Nabriva Therapeutics plc Ordinary Shares Ireland
NBRV
$3.27M 0.02%
3,753
– –
TNXP icon
84
Tonix Pharmaceuticals
TNXP
$215M
– –
0
– –
TRIL
85
DELISTED
Trillium Therapeutics Inc.
TRIL
$3.07M 0.02%
511,763
+102,440
+25% +$653K
KRYS icon
86
Krystal Biotech
KRYS
$10.3B
$2.97M 0.02%
200,000
– –
RIGL icon
87
Rigel Pharmaceuticals
RIGL
$857M
$2.95M 0.02%
104,161
-147,727
-59% -$5.26M
LUMO
88
DELISTED
Lumos Pharma, Inc. Common Stock
LUMO
$2.42M 0.02%
56,364
– –
OVID icon
89
Ovid Therapeutics
OVID
$547M
$1.93M 0.01%
247,733
– –
RARX
90
DELISTED
Ra Pharmaceuticals, Inc. Common Stock
RARX
$1.77M 0.01%
177,952
– –
MDWD icon
91
MediWound
MDWD
$171M
$1.56M 0.01%
32,286
– –
RCUS icon
92
Arcus Biosciences
RCUS
$3.86B
$1.49M 0.01%
+121,534
New +$1.91M
CLLS
93
Cellectis
CLLS
$342M
$1.42M 0.01%
50,000
– –
TRVN
94
DELISTED
Trevena, Inc.
TRVN
$1.37M 0.01%
1,520
– –
ABUS icon
95
Arbutus Biopharma
ABUS
$1.03B
$1.32M 0.01%
180,582
– –
CRBP icon
96
Corbus Pharmaceuticals
CRBP
$201M
$1.25M 0.01%
8,248
-13,776
-63% -$2.5M
RNAC icon
97
Cartesian Therapeutics
RNAC
$304M
$1.24M 0.01%
3,125
– –
ADAP
98
DELISTED
Adaptimmune Therapeutics
ADAP
$1.19M 0.01%
100,000
– –
VIRX
99
DELISTED
Viracta Therapeutics, Inc. Common Stock
VIRX
$1.18M 0.01%
15,905
– –
DVAX
100
DELISTED
Dynavax Technologies
DVAX
$1.14M 0.01%
75,000
– –
1 2 3
4
5

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Julian Baker's Q2 2018 Portfolio in Review

As of Q2 2018, Julian Baker held 124 positions worth $13.3B, up 13% from $11.8B the previous quarter. Its ten largest holdings account for 84% of the portfolio.

Julian Baker deployed $1.01B of net new capital in Q2 2018, opening 10 new positions and adding to 16 existing holdings. Its largest new stake was Kiniksa Pharmaceuticals: 3,000,000 shares worth $52M.

By sector, the portfolio is most concentrated in Healthcare at 99% of assets, up from 99% a quarter earlier, followed by Technology.

On the sell side, the largest reduction was Exelixis, an estimated $13.4M trimmed.

  • Julian Baker's largest Q2 2018 buy was Kiniksa Pharmaceuticals: 3,000,000 shares worth $52M.
  • Julian Baker added most to BeOne Medicines Ltd in Q2 2018, an estimated $1.09B increase.
  • Julian Baker's biggest Q2 2018 reduction was Exelixis, cutting an estimated $13.4M.
  • Julian Baker fully exited AveXis, Inc. Common Stock in Q2 2018, selling an estimated $144M.
  • Julian Baker's ten largest holdings make up 84% of its $13.3B portfolio in Q2 2018.
  • Julian Baker opened 10 new positions and closed 5 in Q2 2018.
  • Julian Baker's portfolio value rose 13% quarter-over-quarter to $13.3B.

Based on Baker Bros. Advisors's 13F filing for Q2 2018, filed 14 Aug 2018.