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JB

Julian Baker Baker Bros. Advisors

AUM $20B
1-Year Est. Return 154.41%
 

Julian Baker is co-managing member of Baker Bros. Advisors, a firm renowned for deep specialization in biotechnology and life sciences. The firm is known for concentrated positions, long holding periods, and scientific diligence that goes well beyond typical generalist research. Baker Bros. filings are closely watched by healthcare investors for signals in clinical-stage and commercial biotech.

This Fund
S&P 500
This Quarter Est. Return
+22.77%
1 Year Est. Return
+154.41%
3 Year Est. Return
+448.58%
5 Year Est. Return
+670.61%
10 Year Est. Return
+4,743.65%
AUM
$12.2B
AUM Growth
+$2.02B
Cap. Flow
+$1.08B
Cap. Flow %
8.87%
Top 10 Hldgs %
86.71%
Holding
137
New
4
Increased
21
Reduced
9
Closed
18

Top Buys

Rank Stock Value
1
INCY icon
Incyte
INCY
+$1.35B
2
AVXS
AveXis, Inc. Common Stock
AVXS
+$11.4M
3
LJPC
La Jolla Pharmaceutical Company
LJPC
+$9.33M
4
ASND icon
Ascendis Pharma A/S
ASND
+$8.29M
5
NGNE icon
Neurogene
NGNE
+$6.99M

Top Sells

Rank Stock Value
1
ABBV icon
AbbVie
ABBV
+$106M
2
DSCI
Derma Sciences, Inc. Common Stock (DE)
DSCI
+$19.5M
3
ARRY
Array Biopharma Inc
ARRY
+$10.6M
4
EXEL icon
Exelixis
EXEL
+$8.13M
5
ARCT icon
Arcturus Therapeutics
ARCT
+$4.91M

Sector Composition

Rank Sector Weight
1 Healthcare 98.27%
2 Technology 0%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
RNAC icon
76
Cartesian Therapeutics
RNAC
$304M
$2.52M 0.02%
5,857
– –
JNCE
77
DELISTED
Jounce Therapeutics, Inc. Common Stock
JNCE
$2.2M 0.02%
+100,000
New +$2.12M
DMTX
78
DELISTED
Dimension Therapeutics, Inc
DMTX
$2.19M 0.02%
1,251,881
– –
TNXP icon
79
Tonix Pharmaceuticals
TNXP
$215M
– –
0
– –
CBIO
80
Crescent Biopharma
CBIO
$637M
$2.07M 0.02%
3,812
– –
NTRA icon
81
Natera
NTRA
$47.9B
$2.03M 0.02%
228,676
-20,593
-8% -$196K
FSTX
82
DELISTED
F-star Therapeutics, Inc. Common Stock
FSTX
$1.95M 0.02%
54,825
– –
INFI
83
DELISTED
Infinity Pharmaceuticals, Inc.
INFI
$1.88M 0.02%
580,400
– –
NVIV
84
DELISTED
InVivo Therapeutics Holdings Corp
NVIV
$1.62M 0.01%
21
– –
MDWD icon
85
MediWound
MDWD
$171M
$1.49M 0.01%
32,286
– –
SYRE icon
86
Spyre Therapeutics
SYRE
$9.39B
$1.42M 0.01%
7,599
-8,570
-53% -$1.21M
MCRB icon
87
Seres Therapeutics
MCRB
$45.8M
$1.41M 0.01%
6,250
– –
FLGT icon
88
Fulgent Genetics
FLGT
$548M
$1.36M 0.01%
125,000
– –
MYOK
89
DELISTED
MyoKardia, Inc. Common Stock
MYOK
$1.31M 0.01%
100,000
– –
CLLS
90
Cellectis
CLLS
$342M
$1.2M 0.01%
50,000
– –
JUNO
91
DELISTED
Juno Therapeutics, Inc.
JUNO
$1.11M 0.01%
50,000
-30,000
-38% -$643K
CRBP icon
92
Corbus Pharmaceuticals
CRBP
$201M
$1.07M 0.01%
4,338
-4,333
-50% -$1.06M
IMDZ
93
DELISTED
Immune Design Corp.
IMDZ
$1.01M 0.01%
148,937
– –
AFMD
94
DELISTED
Affimed
AFMD
$920K 0.01%
40,000
– –
MDGL icon
95
Madrigal Pharmaceuticals
MDGL
$11.9B
$890K 0.01%
57,762
– –
XLRN
96
DELISTED
Acceleron Pharma
XLRN
$761K 0.01%
28,765
– –
CMRX
97
DELISTED
Chimerix, Inc.
CMRX
$735K 0.01%
115,216
– –
FPRX
98
DELISTED
Five Prime Therapeutics, Inc.
FPRX
$696K 0.01%
19,247
– –
PTN
99
Palatin Technologies
PTN
$17.2M
$671K 0.01%
1,640
– –
ABUS icon
100
Arbutus Biopharma
ABUS
$1.03B
$587K ﹤0.01%
180,582
– –
2 3
4
5 6

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Julian Baker's Q1 2017 Portfolio in Review

As of Q1 2017, Julian Baker held 137 positions worth $12.2B, up 20% from $10.2B the previous quarter. Its ten largest holdings account for 87% of the portfolio.

Julian Baker deployed $1.08B of net new capital in Q1 2017, opening 4 new positions and adding to 21 existing holdings. Its largest new stake was AnaptysBio: 150,000 shares worth $4.16M.

By sector, the portfolio is most concentrated in Healthcare at 98% of assets, up from 88% a quarter earlier, followed by Technology.

On the sell side, the largest reduction was Array Biopharma Inc, an estimated $10.6M trimmed.

  • Julian Baker's largest Q1 2017 buy was AnaptysBio: 150,000 shares worth $4.16M.
  • Julian Baker added most to Incyte in Q1 2017, an estimated $1.35B increase.
  • Julian Baker's biggest Q1 2017 reduction was Array Biopharma Inc, cutting an estimated $10.6M.
  • Julian Baker fully exited AbbVie in Q1 2017, selling an estimated $106M.
  • Julian Baker's ten largest holdings make up 87% of its $12.2B portfolio in Q1 2017.
  • Julian Baker opened 4 new positions and closed 18 in Q1 2017.
  • Julian Baker's portfolio value rose 20% quarter-over-quarter to $12.2B.

Based on Baker Bros. Advisors's 13F filing for Q1 2017, filed 15 May 2017.