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JB

Julian Baker Baker Bros. Advisors

AUM $20B
1-Year Est. Return 154.41%
 

Julian Baker is co-managing member of Baker Bros. Advisors, a firm renowned for deep specialization in biotechnology and life sciences. The firm is known for concentrated positions, long holding periods, and scientific diligence that goes well beyond typical generalist research. Baker Bros. filings are closely watched by healthcare investors for signals in clinical-stage and commercial biotech.

This Fund
S&P 500
This Quarter Est. Return
+17.28%
1 Year Est. Return
+154.41%
3 Year Est. Return
+448.58%
5 Year Est. Return
+670.61%
10 Year Est. Return
+4,743.65%
AUM
$11B
AUM Growth
+$1.48B
Cap. Flow
-$1.03B
Cap. Flow %
-9.36%
Top 10 Hldgs %
83.4%
Holding
140
New
7
Increased
14
Reduced
16
Closed
6

Top Buys

Rank Stock Value
1
AMRN
Amarin Corp
AMRN
+$55.6M
2
ACAD icon
Acadia Pharmaceuticals
ACAD
+$44.2M
3
SGEN
Seagen Inc. Common Stock
SGEN
+$40.8M
4
NGNE icon
Neurogene
NGNE
+$28.1M
5
EXEL icon
Exelixis
EXEL
+$25.4M

Top Sells

Rank Stock Value
1
XNPT
XENOPORT, INC.
XNPT
+$24.5M
2
MDVN
MEDIVATION, INC.
MDVN
+$19.9M
3
NVAX icon
Novavax
NVAX
+$17.3M
4
BCRX icon
BioCryst Pharmaceuticals
BCRX
+$16.2M
5
INSM icon
Insmed
INSM
+$13.8M

Sector Composition

Rank Sector Weight
1 Healthcare 88.07%
2 Technology 0.01%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
NVIV
76
DELISTED
InVivo Therapeutics Holdings Corp
NVIV
$2.72M 0.02%
21
– –
ECYT
77
DELISTED
Endocyte, Inc. Common Stock
ECYT
$2.69M 0.02%
868,983
-261,594
-23% -$815K
SYRE icon
78
Spyre Therapeutics
SYRE
$9.39B
$2.59M 0.02%
16,169
– –
RNAC icon
79
Cartesian Therapeutics
RNAC
$304M
$2.55M 0.02%
5,965
– –
OSIR
80
DELISTED
Osiris Therapeutics, Inc. Common Stock
OSIR
$2.48M 0.02%
499,193
– –
NBRV
81
DELISTED
Nabriva Therapeutics plc Ordinary Shares Ireland
NBRV
$2.47M 0.02%
1,400
– –
JUNO
82
DELISTED
Juno Therapeutics, Inc.
JUNO
$2.4M 0.02%
80,000
– –
EPZM
83
DELISTED
Epizyme, Inc
EPZM
$2.29M 0.02%
232,481
– –
KPTI icon
84
Karyopharm Therapeutics
KPTI
$44.5M
$2.11M 0.02%
14,466
– –
IONS icon
85
Ionis Pharmaceuticals
IONS
$9.93B
$2.09M 0.02%
57,140
– –
ENTA icon
86
Enanta Pharmaceuticals
ENTA
$392M
$2M 0.02%
75,357
– –
SCYX icon
87
SCYNEXIS
SCYX
$50.7M
$1.81M 0.02%
5,845
– –
ASMB icon
88
Assembly Biosciences
ASMB
$700M
$1.8M 0.02%
20,833
– –
QURE icon
89
uniQure
QURE
$3.36B
$1.76M 0.02%
230,000
– –
MDWD icon
90
MediWound
MDWD
$171M
$1.74M 0.02%
32,286
– –
ISEE
91
DELISTED
IVERIC bio, Inc. Common Stock
ISEE
$1.64M 0.01%
35,649
– –
MYOK
92
DELISTED
MyoKardia, Inc. Common Stock
MYOK
$1.63M 0.01%
+100,000
New +$1.81M
MCRB icon
93
Seres Therapeutics
MCRB
$45.8M
$1.54M 0.01%
6,250
– –
PTN
94
Palatin Technologies
PTN
$17.2M
$1.29M 0.01%
1,640
– –
CLLS
95
Cellectis
CLLS
$342M
$1.2M 0.01%
50,000
– –
CLCD
96
DELISTED
CoLucid Pharmaceuticals, Inc.
CLCD
$1.16M 0.01%
+30,310
New +$448K
FLGT icon
97
Fulgent Genetics
FLGT
$548M
$1.15M 0.01%
+125,000
New +$1.15M
IMDZ
98
DELISTED
Immune Design Corp.
IMDZ
$1.13M 0.01%
148,937
– –
AFMD
99
DELISTED
Affimed
AFMD
$1.11M 0.01%
40,000
– –
ALDX icon
100
Aldeyra Therapeutics
ALDX
$91.7M
$1.11M 0.01%
142,000
– –
2 3
4
5 6

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Julian Baker's Q3 2016 Portfolio in Review

As of Q3 2016, Julian Baker held 140 positions worth $11B, up 16% from $9.54B the previous quarter. Its ten largest holdings account for 83% of the portfolio.

Julian Baker withdrew a net $1.03B in Q3 2016, closing 6 positions and reducing 16 holdings. Its most notable exit was XENOPORT, INC., an estimated $24.5M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 88% of assets, up from 86% a quarter earlier, followed by Technology.

Against the trend, Julian Baker opened a new position in ContraFect Corporation worth $10M.

  • Julian Baker's largest Q3 2016 buy was ContraFect Corporation: 5,057 shares worth $10M.
  • Julian Baker added most to Amarin Corp in Q3 2016, an estimated $55.6M increase.
  • Julian Baker's biggest Q3 2016 reduction was BioCryst Pharmaceuticals, cutting an estimated $16.2M.
  • Julian Baker fully exited XENOPORT, INC. in Q3 2016, selling an estimated $24.5M.
  • Julian Baker's ten largest holdings make up 83% of its $11B portfolio in Q3 2016.
  • Julian Baker opened 7 new positions and closed 6 in Q3 2016.
  • Julian Baker's portfolio value rose 16% quarter-over-quarter to $11B.

Based on Baker Bros. Advisors's 13F filing for Q3 2016, filed 14 Nov 2016.