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JB

Julian Baker Baker Bros. Advisors

AUM $20B
1-Year Est. Return 154.41%
 

Julian Baker is co-managing member of Baker Bros. Advisors, a firm renowned for deep specialization in biotechnology and life sciences. The firm is known for concentrated positions, long holding periods, and scientific diligence that goes well beyond typical generalist research. Baker Bros. filings are closely watched by healthcare investors for signals in clinical-stage and commercial biotech.

This Fund
S&P 500
This Quarter Est. Return
+6.87%
1 Year Est. Return
+154.41%
3 Year Est. Return
+448.58%
5 Year Est. Return
+670.61%
10 Year Est. Return
+4,743.65%
AUM
$9.54B
AUM Growth
+$55.8M
Cap. Flow
-$1.48B
Cap. Flow %
-15.48%
Top 10 Hldgs %
82.65%
Holding
142
New
10
Increased
13
Reduced
15
Closed
7

Top Buys

Rank Stock Value
1
NTLA icon
Intellia Therapeutics
NTLA
+$28.3M
2
ACAD icon
Acadia Pharmaceuticals
ACAD
+$10.1M
3
MRUS
Merus
MRUS
+$9.82M
4
AAAP
Advanced Accelerator Applications S.A.
AAAP
+$6.94M
5
ALDR
Alder Biopharmaceuticals
ALDR
+$5.88M

Top Sells

Rank Stock Value
1
ANAC
ANACOR PHARMACEUTICALS INC COM
ANAC
+$274M
2
MRTX
Mirati Therapeutics, Inc. Common Stock
MRTX
+$15.9M
3
OMER icon
Omeros
OMER
+$11.5M
4
GBT
Global Blood Therapeutics, Inc.
GBT
+$9.52M
5
IMGN
Immunogen Inc
IMGN
+$9.01M

Sector Composition

Rank Sector Weight
1 Healthcare 86.04%
2 Technology 0.01%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
NBRV
76
DELISTED
Nabriva Therapeutics plc Ordinary Shares Ireland
NBRV
$2.63M 0.03%
1,400
– –
ADMS
77
DELISTED
Adamas Pharmaceuticals
ADMS
$2.61M 0.03%
172,630
– –
OSIR
78
DELISTED
Osiris Therapeutics, Inc. Common Stock
OSIR
$2.54M 0.03%
499,193
– –
RNAC icon
79
Cartesian Therapeutics
RNAC
$304M
$2.5M 0.03%
+5,965
New +$2.51M
VIRX
80
DELISTED
Viracta Therapeutics, Inc. Common Stock
VIRX
$2.44M 0.03%
21,190
– –
TARA icon
81
Protara Therapeutics
TARA
$228M
$2.4M 0.03%
7,465
– –
EPZM
82
DELISTED
Epizyme, Inc
EPZM
$2.38M 0.03%
232,481
– –
NVIV
83
DELISTED
InVivo Therapeutics Holdings Corp
NVIV
$2.31M 0.02%
21
– –
STML
84
DELISTED
Stemline Therapeutics, Inc.
STML
$2.26M 0.02%
333,497
– –
AUPH icon
85
Aurinia Pharmaceuticals
AUPH
$2.22B
$2.12M 0.02%
711,499
– –
SYRE icon
86
Spyre Therapeutics
SYRE
$9.39B
$1.97M 0.02%
+16,169
New +$3.1M
TRIL
87
DELISTED
Trillium Therapeutics Inc.
TRIL
$1.9M 0.02%
211,792
– –
ISEE
88
DELISTED
IVERIC bio, Inc. Common Stock
ISEE
$1.82M 0.02%
35,649
– –
SVRA icon
89
Savara
SVRA
$1.15B
$1.82M 0.02%
55,258
-13,277
-19% -$327K
MDWD icon
90
MediWound
MDWD
$171M
$1.78M 0.02%
32,286
– –
AMRN
91
Amarin Corp
AMRN
$298M
$1.73M 0.02%
40,093
– –
QURE icon
92
uniQure
QURE
$3.36B
$1.7M 0.02%
230,000
– –
ENTA icon
93
Enanta Pharmaceuticals
ENTA
$392M
$1.66M 0.02%
75,357
– –
CYTR
94
DELISTED
CytRx Corp
CYTR
$1.47M 0.02%
109,999
– –
KPTI icon
95
Karyopharm Therapeutics
KPTI
$44.5M
$1.46M 0.02%
14,466
– –
ASMB icon
96
Assembly Biosciences
ASMB
$700M
$1.39M 0.01%
20,833
– –
GWPH
97
DELISTED
GW Pharmaceuticals Plc American Depositary Shares
GWPH
$1.37M 0.01%
15,000
– –
IONS icon
98
Ionis Pharmaceuticals
IONS
$9.93B
$1.33M 0.01%
57,140
– –
CLLS
99
Cellectis
CLLS
$342M
$1.33M 0.01%
50,000
– –
IMDZ
100
DELISTED
Immune Design Corp.
IMDZ
$1.22M 0.01%
148,937
– –
2 3
4
5 6

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Julian Baker's Q2 2016 Portfolio in Review

As of Q2 2016, Julian Baker held 142 positions worth $9.54B, up 0.59% from $9.48B the previous quarter. Its ten largest holdings account for 83% of the portfolio.

Julian Baker withdrew a net $1.48B in Q2 2016, closing 7 positions and reducing 15 holdings. Its most notable exit was ANACOR PHARMACEUTICALS INC COM, an estimated $274M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 86% of assets, up from 82% a quarter earlier, followed by Technology.

Against the trend, Julian Baker opened a new position in Intellia Therapeutics worth $22.7M.

  • Julian Baker's largest Q2 2016 buy was Intellia Therapeutics: 1,062,120 shares worth $22.7M.
  • Julian Baker added most to Acadia Pharmaceuticals in Q2 2016, an estimated $10.1M increase.
  • Julian Baker's biggest Q2 2016 reduction was Mirati Therapeutics, Inc. Common Stock, cutting an estimated $15.9M.
  • Julian Baker fully exited ANACOR PHARMACEUTICALS INC COM in Q2 2016, selling an estimated $274M.
  • Julian Baker's ten largest holdings make up 83% of its $9.54B portfolio in Q2 2016.
  • Julian Baker opened 10 new positions and closed 7 in Q2 2016.
  • Julian Baker's portfolio value rose 0.59% quarter-over-quarter to $9.54B.

Based on Baker Bros. Advisors's 13F filing for Q2 2016, filed 15 Aug 2016.