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JB

Julian Baker Baker Bros. Advisors

AUM $20B
1-Year Est. Return 154.41%
 

Julian Baker is co-managing member of Baker Bros. Advisors, a firm renowned for deep specialization in biotechnology and life sciences. The firm is known for concentrated positions, long holding periods, and scientific diligence that goes well beyond typical generalist research. Baker Bros. filings are closely watched by healthcare investors for signals in clinical-stage and commercial biotech.

This Fund
S&P 500
This Quarter Est. Return
+13.19%
1 Year Est. Return
+154.41%
3 Year Est. Return
+448.58%
5 Year Est. Return
+670.61%
10 Year Est. Return
+4,743.65%
AUM
$12.1B
AUM Growth
+$1.25B
Cap. Flow
-$1.53B
Cap. Flow %
-12.71%
Top 10 Hldgs %
75.84%
Holding
141
New
6
Increased
25
Reduced
5
Closed
8

Sector Composition

Rank Sector Weight
1 Healthcare 78.52%
2 Technology 0.01%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
EPZM
76
DELISTED
Epizyme, Inc
EPZM
$3.72M 0.03%
232,481
IONS icon
77
Ionis Pharmaceuticals
IONS
$9.93B
$3.54M 0.03%
57,140
JUNO
78
DELISTED
Juno Therapeutics, Inc.
JUNO
$3.52M 0.03%
80,000
VTAE
79
DELISTED
VITAE PHARMACEUTICALS INC COMMON STOCK
VTAE
$3.4M 0.03%
187,597
NBRV
80
DELISTED
Nabriva Therapeutics plc Ordinary Shares Ireland
NBRV
$3.37M 0.03%
1,400
SRRA
81
DELISTED
Sierra Oncology, Inc. Common Stock
SRRA
$3.01M 0.02%
5,000
IMDZ
82
DELISTED
Immune Design Corp.
IMDZ
$2.99M 0.02%
148,937
KPTI icon
83
Karyopharm Therapeutics
KPTI
$44.5M
$2.88M 0.02%
14,466
AFMD
84
DELISTED
Affimed
AFMD
$2.85M 0.02%
40,000
FLXN
85
DELISTED
Flexion Therapeutics, Inc.
FLXN
$2.83M 0.02%
+146,642
New +$2.55M
ISEE
86
DELISTED
IVERIC bio, Inc. Common Stock
ISEE
$2.8M 0.02%
35,649
NTRA icon
87
Natera
NTRA
$47.9B
$2.7M 0.02%
250,000
TRIL
88
DELISTED
Trillium Therapeutics Inc.
TRIL
$2.67M 0.02%
211,792
+148,778
+236% +$2.07M
ENTA icon
89
Enanta Pharmaceuticals
ENTA
$392M
$2.49M 0.02%
75,357
NBSE
90
DELISTED
NeuBase Therapeutics, Inc. Common Stock
NBSE
$2.27M 0.02%
926
STML
91
DELISTED
Stemline Therapeutics, Inc.
STML
$2.1M 0.02%
333,497
SVRA icon
92
Savara
SVRA
$1.15B
$2.02M 0.02%
68,535
+1,286
+2% +$40K
IRWD icon
93
Ironwood Pharmaceuticals
IRWD
$709M
$1.96M 0.02%
201,981
MDWD icon
94
MediWound
MDWD
$171M
$1.92M 0.02%
32,143
ASMB icon
95
Assembly Biosciences
ASMB
$700M
$1.88M 0.02%
20,833
DVAX
96
DELISTED
Dynavax Technologies
DVAX
$1.81M 0.02%
75,000
AUPH icon
97
Aurinia Pharmaceuticals
AUPH
$2.22B
$1.79M 0.01%
711,499
CYTR
98
DELISTED
CytRx Corp
CYTR
$1.75M 0.01%
109,999
-109,999
-50% -$1.89M
CLLS
99
Cellectis
CLLS
$342M
$1.55M 0.01%
50,000
MRNS
100
DELISTED
Marinus Pharmaceuticals, Inc
MRNS
$1.53M 0.01%
50,000

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Julian Baker's Q4 2015 Portfolio in Review

As of Q4 2015, Julian Baker held 141 positions worth $12.1B, up 12% from $10.8B the previous quarter. Its ten largest holdings account for 76% of the portfolio.

Julian Baker withdrew a net $1.53B in Q4 2015, closing 8 positions and reducing 5 holdings. Its most notable exit was Clovis Oncology, Inc., an estimated $18.6M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 79% of assets, up from 78% a quarter earlier, followed by Technology.

Against the trend, Julian Baker opened a new position in Alkermes worth $19.9M.

  • Julian Baker's largest Q4 2015 buy was Alkermes: 250,251 shares worth $19.9M.
  • Julian Baker added most to Acorda Therapeutics in Q4 2015, an estimated $90.4M increase.
  • Julian Baker's biggest Q4 2015 reduction was XENOPORT, INC., cutting an estimated $17M.
  • Julian Baker fully exited Clovis Oncology, Inc. in Q4 2015, selling an estimated $18.6M.
  • Julian Baker's ten largest holdings make up 76% of its $12.1B portfolio in Q4 2015.
  • Julian Baker opened 6 new positions and closed 8 in Q4 2015.
  • Julian Baker's portfolio value rose 12% quarter-over-quarter to $12.1B.

Based on Baker Bros. Advisors's 13F filing for Q4 2015, filed 16 Feb 2016.