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JB

Julian Baker Baker Bros. Advisors

AUM $20B
1-Year Est. Return 154.41%
 

Julian Baker is co-managing member of Baker Bros. Advisors, a firm renowned for deep specialization in biotechnology and life sciences. The firm is known for concentrated positions, long holding periods, and scientific diligence that goes well beyond typical generalist research. Baker Bros. filings are closely watched by healthcare investors for signals in clinical-stage and commercial biotech.

This Fund
S&P 500
This Quarter Est. Return
-6.24%
1 Year Est. Return
+154.41%
3 Year Est. Return
+448.58%
5 Year Est. Return
+670.61%
10 Year Est. Return
+4,743.65%
AUM
$10.8B
AUM Growth
-$577M
Cap. Flow
-$347M
Cap. Flow %
-3.21%
Top 10 Hldgs %
77.46%
Holding
139
New
12
Increased
27
Reduced
8
Closed
6

Top Buys

Rank Stock Value
1
INCY icon
Incyte
INCY
+$517M
2
SGEN
Seagen Inc. Common Stock
SGEN
+$232M
3
DBVT
DBV Technologies
DBVT
+$142M
4
ANAC
ANACOR PHARMACEUTICALS INC COM
ANAC
+$66.6M
5
NGNE icon
Neurogene
NGNE
+$63.9M

Top Sells

Rank Stock Value
1
XOMA
Xoma
XOMA
+$57M
2
KYTH
KYTHERA BIOPHARMACEUTICALS, INC COM
KYTH
+$29.2M
3
ALDR
Alder Biopharmaceuticals
ALDR
+$16.1M
4
OMER icon
Omeros
OMER
+$9.78M
5
DYAX
DYAX CORPORATION
DYAX
+$8.72M

Sector Composition

Rank Sector Weight
1 Healthcare 77.98%
2 Technology 0.01%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
MCRB icon
76
Seres Therapeutics
MCRB
$45.8M
$3.71M 0.03%
6,250
– –
OMER icon
77
Omeros
OMER
$1.39B
$3.69M 0.03%
336,226
-628,395
-65% -$9.78M
NBRV
78
DELISTED
Nabriva Therapeutics plc Ordinary Shares Ireland
NBRV
$3.33M 0.03%
+1,400
New +$3.71M
JUNO
79
DELISTED
Juno Therapeutics, Inc.
JUNO
$3.25M 0.03%
80,000
– –
CYTR
80
DELISTED
CytRx Corp
CYTR
$3.13M 0.03%
219,998
– –
EPZM
81
DELISTED
Epizyme, Inc
EPZM
$2.99M 0.03%
232,481
– –
STML
82
DELISTED
Stemline Therapeutics, Inc.
STML
$2.94M 0.03%
333,497
– –
SVRA icon
83
Savara
SVRA
$1.15B
$2.73M 0.03%
67,249
– –
ENTA icon
84
Enanta Pharmaceuticals
ENTA
$392M
$2.72M 0.03%
75,357
– –
NTRA icon
85
Natera
NTRA
$47.9B
$2.71M 0.03%
+250,000
New +$4.24M
VIRX
86
DELISTED
Viracta Therapeutics, Inc. Common Stock
VIRX
$2.59M 0.02%
15,238
– –
AFMD
87
DELISTED
Affimed
AFMD
$2.47M 0.02%
40,000
– –
ASMB icon
88
Assembly Biosciences
ASMB
$700M
$2.39M 0.02%
20,833
– –
IONS icon
89
Ionis Pharmaceuticals
IONS
$9.93B
$2.31M 0.02%
57,140
– –
KPTI icon
90
Karyopharm Therapeutics
KPTI
$44.5M
$2.29M 0.02%
14,466
– –
VTAE
91
DELISTED
VITAE PHARMACEUTICALS INC COMMON STOCK
VTAE
$2.06M 0.02%
187,597
– –
AUPH icon
92
Aurinia Pharmaceuticals
AUPH
$2.22B
$2M 0.02%
711,499
– –
DVAX
93
DELISTED
Dynavax Technologies
DVAX
$1.84M 0.02%
+75,000
New +$2.12M
BLPH
94
DELISTED
Bellerophon Therapeutics, Inc.
BLPH
$1.83M 0.02%
23,529
+196
+0.8% +$15.1K
IMDZ
95
DELISTED
Immune Design Corp.
IMDZ
$1.82M 0.02%
148,937
– –
IRWD icon
96
Ironwood Pharmaceuticals
IRWD
$709M
$1.76M 0.02%
201,981
– –
LOXO
97
DELISTED
Loxo Oncology, Inc
LOXO
$1.75M 0.02%
100,000
– –
MDWD icon
98
MediWound
MDWD
$171M
$1.72M 0.02%
32,143
– –
MRNS
99
DELISTED
Marinus Pharmaceuticals, Inc
MRNS
$1.67M 0.02%
50,000
– –
PTN
100
Palatin Technologies
PTN
$17.2M
$1.66M 0.02%
1,640
– –
2 3
4
5 6

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Julian Baker's Q3 2015 Portfolio in Review

As of Q3 2015, Julian Baker held 139 positions worth $10.8B, down 5.1% from $11.4B the previous quarter. Its ten largest holdings account for 77% of the portfolio.

Julian Baker withdrew a net $347M in Q3 2015, closing 6 positions and reducing 8 holdings. Its most notable exit was Xoma, an estimated $57M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 78% of assets, up from 78% a quarter earlier, followed by Technology.

Against the trend, Julian Baker opened a new position in MEDIVATION, INC. worth $28M.

  • Julian Baker's largest Q3 2015 buy was MEDIVATION, INC.: 659,752 shares worth $28M.
  • Julian Baker added most to Incyte in Q3 2015, an estimated $517M increase.
  • Julian Baker's biggest Q3 2015 reduction was Alder Biopharmaceuticals, cutting an estimated $16.1M.
  • Julian Baker fully exited Xoma in Q3 2015, selling an estimated $57M.
  • Julian Baker's ten largest holdings make up 77% of its $10.8B portfolio in Q3 2015.
  • Julian Baker opened 12 new positions and closed 6 in Q3 2015.
  • Julian Baker's portfolio value fell 5.1% quarter-over-quarter to $10.8B.

Based on Baker Bros. Advisors's 13F filing for Q3 2015, filed 16 Nov 2015.