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JB

Julian Baker Baker Bros. Advisors

AUM $20B
1-Year Est. Return 154.41%
 

Julian Baker is co-managing member of Baker Bros. Advisors, a firm renowned for deep specialization in biotechnology and life sciences. The firm is known for concentrated positions, long holding periods, and scientific diligence that goes well beyond typical generalist research. Baker Bros. filings are closely watched by healthcare investors for signals in clinical-stage and commercial biotech.

This Fund
S&P 500
This Quarter Est. Return
-6.24%
1 Year Est. Return
+154.41%
3 Year Est. Return
+448.58%
5 Year Est. Return
+670.61%
10 Year Est. Return
+4,743.65%
AUM
$10.8B
AUM Growth
-$577M
Cap. Flow
-$347M
Cap. Flow %
-3.21%
Top 10 Hldgs %
77.46%
Holding
139
New
12
Increased
27
Reduced
8
Closed
6

Top Buys

Rank Stock Value
1
INCY icon
Incyte
INCY
+$517M
2
SGEN
Seagen Inc. Common Stock
SGEN
+$232M
3
DBVT
DBV Technologies
DBVT
+$142M
4
ANAC
ANACOR PHARMACEUTICALS INC COM
ANAC
+$66.6M
5
NGNE icon
Neurogene
NGNE
+$63.9M

Top Sells

Rank Stock Value
1
XOMA
Xoma
XOMA
+$57M
2
KYTH
KYTHERA BIOPHARMACEUTICALS, INC COM
KYTH
+$29.2M
3
ALDR
Alder Biopharmaceuticals
ALDR
+$16.1M
4
OMER icon
Omeros
OMER
+$9.78M
5
DYAX
DYAX CORPORATION
DYAX
+$8.72M

Sector Composition

Rank Sector Weight
1 Healthcare 77.98%
2 Technology 0.01%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
XNCR icon
51
Xencor
XNCR
$2.07B
$10.7M 0.1%
872,072
– –
IOVA icon
52
Iovance Biotherapeutics
IOVA
$3.76B
$10.5M 0.1%
1,817,429
– –
ARCT icon
53
Arcturus Therapeutics
ARCT
$382M
$9.9M 0.09%
234,267
-21,429
-8% -$1.13M
AKTX
54
Akari Therapeutics
AKTX
$15.3M
$9.5M 0.09%
+495
New +$5.86M
CNCE
55
DELISTED
Concert Pharmaceuticals, Inc.
CNCE
$9.31M 0.09%
495,908
– –
OSIR
56
DELISTED
Osiris Therapeutics, Inc. Common Stock
OSIR
$9.22M 0.09%
499,193
– –
GBT
57
DELISTED
Global Blood Therapeutics, Inc.
GBT
$8.43M 0.08%
+200,000
New +$9.44M
ASND icon
58
Ascendis Pharma A/S
ASND
$16.6B
$7.71M 0.07%
435,540
+335,540
+336% +$6.53M
MGNX icon
59
MacroGenics
MGNX
$261M
$7.45M 0.07%
347,776
+42,733
+14% +$1.34M
AGIO icon
60
Agios Pharmaceuticals
AGIO
$1.98B
$7.06M 0.07%
100,000
– –
DERM
61
DELISTED
Dermira, Inc.
DERM
$6.42M 0.06%
275,000
+175,000
+175% +$4.25M
AIMT
62
DELISTED
Aimmune Therapeutics
AIMT
$6.33M 0.06%
+250,000
New +$5.84M
NDRM
63
DELISTED
NeuroDerm Ltd. Ordinary Shares
NDRM
$6.3M 0.06%
305,000
+55,000
+22% +$1.13M
LGND icon
64
Ligand Pharmaceuticals
LGND
$5.71B
$6.29M 0.06%
117,638
– –
ECYT
65
DELISTED
Endocyte, Inc. Common Stock
ECYT
$6.21M 0.06%
+1,356,552
New +$7.1M
ARWR icon
66
Arrowhead Research
ARWR
$12.3B
$5.82M 0.05%
1,009,509
– –
AERI
67
DELISTED
Aerie Pharmaceuticals
AERI
$5.31M 0.05%
299,356
– –
RXDX
68
DELISTED
Ignyta, Inc.
RXDX
$5.01M 0.05%
571,000
– –
TRVN
69
DELISTED
Trevena, Inc.
TRVN
$4.66M 0.04%
+720
New +$3.55M
SAGE
70
DELISTED
Sage Therapeutics
SAGE
$4.44M 0.04%
105,000
– –
CMRX
71
DELISTED
Chimerix, Inc.
CMRX
$4.4M 0.04%
115,216
– –
AMRN
72
Amarin Corp
AMRN
$298M
$4.26M 0.04%
110,286
– –
SRRA
73
DELISTED
Sierra Oncology, Inc. Common Stock
SRRA
$4.1M 0.04%
+5,000
New +$5.64M
CRIS icon
74
Curis
CRIS
$3.83M
$4.04M 0.04%
1,000
+461
+86% +$2.61M
TARA icon
75
Protara Therapeutics
TARA
$228M
$3.82M 0.04%
6,865
+2,446
+55% +$1.51M
1 2
3
4 5

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Julian Baker's Q3 2015 Portfolio in Review

As of Q3 2015, Julian Baker held 139 positions worth $10.8B, down 5.1% from $11.4B the previous quarter. Its ten largest holdings account for 77% of the portfolio.

Julian Baker withdrew a net $347M in Q3 2015, closing 6 positions and reducing 8 holdings. Its most notable exit was Xoma, an estimated $57M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 78% of assets, up from 78% a quarter earlier, followed by Technology.

Against the trend, Julian Baker opened a new position in MEDIVATION, INC. worth $28M.

  • Julian Baker's largest Q3 2015 buy was MEDIVATION, INC.: 659,752 shares worth $28M.
  • Julian Baker added most to Incyte in Q3 2015, an estimated $517M increase.
  • Julian Baker's biggest Q3 2015 reduction was Alder Biopharmaceuticals, cutting an estimated $16.1M.
  • Julian Baker fully exited Xoma in Q3 2015, selling an estimated $57M.
  • Julian Baker's ten largest holdings make up 77% of its $10.8B portfolio in Q3 2015.
  • Julian Baker opened 12 new positions and closed 6 in Q3 2015.
  • Julian Baker's portfolio value fell 5.1% quarter-over-quarter to $10.8B.

Based on Baker Bros. Advisors's 13F filing for Q3 2015, filed 16 Nov 2015.