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JB

Julian Baker Baker Bros. Advisors

AUM $20B
1-Year Est. Return 154.41%
 

Julian Baker is co-managing member of Baker Bros. Advisors, a firm renowned for deep specialization in biotechnology and life sciences. The firm is known for concentrated positions, long holding periods, and scientific diligence that goes well beyond typical generalist research. Baker Bros. filings are closely watched by healthcare investors for signals in clinical-stage and commercial biotech.

This Fund
S&P 500
This Quarter Est. Return
+4.24%
1 Year Est. Return
+154.41%
3 Year Est. Return
+448.58%
5 Year Est. Return
+670.61%
10 Year Est. Return
+4,743.65%
AUM
$7.94B
AUM Growth
-$224M
Cap. Flow
-$1.92B
Cap. Flow %
-24.14%
Top 10 Hldgs %
74.98%
Holding
115
New
11
Increased
21
Reduced
12
Closed
7

Top Buys

Rank Stock Value
1
BMRN icon
BioMarin Pharmaceuticals
BMRN
+$30.4M
2
ANAC
ANACOR PHARMACEUTICALS INC COM
ANAC
+$19.4M
3
AVNR
AVANIR PHARMACEUTICALS, INC CL A
AVNR
+$16.5M
4
MNK
MALLINCKRODT PUBLIC LIMITED COMPANY
MNK
+$15.8M
5
XNPT
XENOPORT, INC.
XNPT
+$13.6M

Top Sells

Rank Stock Value
1
ITMN
INTERMUNE INC
ITMN
+$209M
2
QCOR
QUESTCOR PHARMA INC
QCOR
+$46.2M
3
CLVS
Clovis Oncology, Inc.
CLVS
+$32.8M
4
SLXP
SALIX PHARMACEUTICALS LTD DEL
SLXP
+$18.1M
5
AEGR
Aegerion Pharmaceuticals
AEGR
+$13.3M

Sector Composition

Rank Sector Weight
1 Healthcare 44.26%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
ARRY
51
DELISTED
Array Biopharma Inc
ARRY
$5.12M 0.06%
1,433,797
– –
NVAX icon
52
Novavax
NVAX
$1.47B
$5.1M 0.06%
61,168
– –
XNCR icon
53
Xencor
XNCR
$2.07B
$5.05M 0.06%
542,363
– –
RXDX
54
DELISTED
Ignyta, Inc.
RXDX
$4.6M 0.06%
571,000
– –
IRWD icon
55
Ironwood Pharmaceuticals
IRWD
$709M
$4.49M 0.06%
413,315
-119,400
-22% -$1.37M
ACHN
56
DELISTED
Achillion Pharmaceuticals
ACHN
$4.38M 0.06%
438,337
– –
STML
57
DELISTED
Stemline Therapeutics, Inc.
STML
$4.22M 0.05%
338,671
– –
INFI
58
DELISTED
Infinity Pharmaceuticals, Inc.
INFI
$4.19M 0.05%
312,025
-312,025
-50% -$3.72M
AKTX
59
Akari Therapeutics
AKTX
$15.3M
$4.11M 0.05%
84
– –
LJPC
60
DELISTED
La Jolla Pharmaceutical Company
LJPC
$4.05M 0.05%
421,631
+200,000
+90% +$1.99M
EIGR
61
DELISTED
Eiger BioPharmaceuticals, Inc.
EIGR
$3.92M 0.05%
+833
New +$4.4M
IONS icon
62
Ionis Pharmaceuticals
IONS
$9.93B
$3.74M 0.05%
96,303
– –
ACGN
63
DELISTED
Aceragen Inc
ACGN
$3.71M 0.05%
11,918
+45
+0.4% +$16.2K
BDSI
64
DELISTED
BioDelivery Sciences International, Inc.
BDSI
$3.59M 0.05%
210,021
-210,984
-50% -$3.06M
LGND icon
65
Ligand Pharmaceuticals
LGND
$5.71B
$3.45M 0.04%
117,660
– –
CYTR
66
DELISTED
CytRx Corp
CYTR
$3.43M 0.04%
225,000
– –
KPTI icon
67
Karyopharm Therapeutics
KPTI
$44.5M
$3.29M 0.04%
6,273
– –
LPCN icon
68
Lipocine
LPCN
$17.2M
$3.06M 0.04%
29,412
– –
ENTA icon
69
Enanta Pharmaceuticals
ENTA
$392M
$2.98M 0.04%
75,357
– –
FOLD
70
DELISTED
Amicus Therapeutics
FOLD
$2.87M 0.04%
481,697
– –
VXRT
71
DELISTED
Vaxart
VXRT
$2.73M 0.03%
100,628
– –
SGYP
72
DELISTED
Synergy Pharmaceuticals, Inc Common Stock
SGYP
$2.71M 0.03%
973,245
-785,026
-45% -$2.85M
ZGNX
73
DELISTED
Zogenix, Inc.
ZGNX
$2.7M 0.03%
293,800
– –
AFMD
74
DELISTED
Affimed
AFMD
$2.52M 0.03%
+40,000
New +$2.5M
SAGE
75
DELISTED
Sage Therapeutics
SAGE
$2.36M 0.03%
+75,000
New +$2.17M
1 2
3
4 5

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Julian Baker's Q3 2014 Portfolio in Review

As of Q3 2014, Julian Baker held 115 positions worth $7.94B, down 2.7% from $8.16B the previous quarter. Its ten largest holdings account for 75% of the portfolio.

Julian Baker withdrew a net $1.92B in Q3 2014, closing 7 positions and reducing 12 holdings. Its most notable exit was INTERMUNE INC, an estimated $209M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 44% of assets, down from 45% a quarter earlier.

Against the trend, Julian Baker opened a new position in MALLINCKRODT PUBLIC LIMITED COMPANY worth $18.2M.

  • Julian Baker's largest Q3 2014 buy was MALLINCKRODT PUBLIC LIMITED COMPANY: 201,856 shares worth $18.2M.
  • Julian Baker added most to BioMarin Pharmaceuticals in Q3 2014, an estimated $30.4M increase.
  • Julian Baker's biggest Q3 2014 reduction was SALIX PHARMACEUTICALS LTD DEL, cutting an estimated $18.1M.
  • Julian Baker fully exited INTERMUNE INC in Q3 2014, selling an estimated $209M.
  • Julian Baker's ten largest holdings make up 75% of its $7.94B portfolio in Q3 2014.
  • Julian Baker opened 11 new positions and closed 7 in Q3 2014.
  • Julian Baker's portfolio value fell 2.7% quarter-over-quarter to $7.94B.

Based on Baker Bros. Advisors's 13F filing for Q3 2014, filed 14 Nov 2014.