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JB

Julian Baker Baker Bros. Advisors

AUM $20B
1-Year Est. Return 154.41%
 

Julian Baker is co-managing member of Baker Bros. Advisors, a firm renowned for deep specialization in biotechnology and life sciences. The firm is known for concentrated positions, long holding periods, and scientific diligence that goes well beyond typical generalist research. Baker Bros. filings are closely watched by healthcare investors for signals in clinical-stage and commercial biotech.

This Fund
S&P 500
This Quarter Est. Return
+45.38%
1 Year Est. Return
+154.41%
3 Year Est. Return
+448.58%
5 Year Est. Return
+670.61%
10 Year Est. Return
+4,743.65%
AUM
$22.7B
AUM Growth
+$6.43B
Cap. Flow
-$298M
Cap. Flow %
-1.32%
Top 10 Hldgs %
85.22%
Holding
124
New
14
Increased
20
Reduced
17
Closed
10

Top Buys

Rank Stock Value
1
MYOK
MyoKardia, Inc. Common Stock
MYOK
+$116M
2
FMTX
Forma Therapeutics Holdings, Inc. Common Stock
FMTX
+$86.7M
3
ADCT icon
ADC Therapeutics
ADCT
+$64M
4
NVTA
Invitae Corporation
NVTA
+$48M
5
SYRE icon
Spyre Therapeutics
SYRE
+$20.3M

Top Sells

Rank Stock Value
1
SGEN
Seagen Inc. Common Stock
SGEN
+$416M
2
RARX
Ra Pharmaceuticals, Inc. Common Stock
RARX
+$101M
3
TCDA
Tricida, Inc. Common Stock
TCDA
+$51.2M
4
NBIX icon
Neurocrine Biosciences
NBIX
+$36.8M
5
PRNB
Principia Biopharma Inc. Common Stock
PRNB
+$23.1M

Sector Composition

Rank Sector Weight
1 Healthcare 99.68%
2 Financials 0.01%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
KNSA icon
26
Kiniksa Pharmaceuticals
KNSA
$6.17B
$71.3M 0.31%
2,799,577
– –
ADAP
27
DELISTED
Adaptimmune Therapeutics
ADAP
$66.8M 0.29%
6,675,181
+2,984,874
+81% +$18.7M
BCRX icon
28
BioCryst Pharmaceuticals
BCRX
$2.44B
$65.6M 0.29%
13,766,405
+2,820,239
+26% +$11.3M
DBVT
29
DBV Technologies
DBVT
$914M
$64.2M 0.28%
1,461,426
– –
ZYME icon
30
Zymeworks
ZYME
$2.05B
$61.6M 0.27%
1,708,472
– –
RYTM icon
31
Rhythm Pharmaceuticals
RYTM
$7.57B
$60.2M 0.27%
2,700,055
-8,145
-0.3% -$159K
NGNE icon
32
Neurogene
NGNE
$773M
$56.4M 0.25%
169,887
– –
CCXI
33
DELISTED
ChemoCentryx, Inc.
CCXI
$54.4M 0.24%
945,221
+86,206
+10% +$4.69M
ALLK
34
DELISTED
Allakos
ALLK
$52.9M 0.23%
735,469
– –
SYRE icon
35
Spyre Therapeutics
SYRE
$9.39B
$40.5M 0.18%
175,184
+106,640
+156% +$20.3M
ASMB icon
36
Assembly Biosciences
ASMB
$700M
$36M 0.16%
128,468
– –
KRYS icon
37
Krystal Biotech
KRYS
$10.3B
$33.9M 0.15%
817,631
-128,840
-14% -$6.2M
PTGX icon
38
Protagonist Therapeutics
PTGX
$9.99B
$33.8M 0.15%
1,911,446
+232,282
+14% +$2.91M
MRUS
39
DELISTED
Merus
MRUS
$32.8M 0.14%
2,037,469
– –
APLS
40
DELISTED
Apellis Pharmaceuticals
APLS
$29.3M 0.13%
896,551
– –
AUPH icon
41
Aurinia Pharmaceuticals
AUPH
$2.22B
$27.7M 0.12%
1,701,929
– –
ALKS icon
42
Alkermes
ALKS
$8.11B
$24.2M 0.11%
1,244,744
– –
GWPH
43
DELISTED
GW Pharmaceuticals Plc American Depositary Shares
GWPH
$22.7M 0.1%
185,045
-185,800
-50% -$21.1M
ALT icon
44
Altimmune
ALT
$605M
$22.6M 0.1%
+2,107,600
New +$11.6M
ADPT icon
45
Adaptive Biotechnologies
ADPT
$4.15B
$22.4M 0.1%
463,539
-280,195
-38% -$10.2M
KRRO icon
46
Korro Bio
KRRO
$194M
$22M 0.1%
18,914
-4,689
-20% -$4.24M
TCDA
47
DELISTED
Tricida, Inc. Common Stock
TCDA
$21.6M 0.1%
787,582
-1,878,433
-70% -$51.2M
NVAX icon
48
Novavax
NVAX
$1.47B
$20.1M 0.09%
+241,376
New +$9.23M
BLUE
49
DELISTED
bluebird bio
BLUE
$16.2M 0.07%
20,458
+17,370
+563% +$13.1M
VXRT
50
DELISTED
Vaxart
VXRT
$14.5M 0.06%
+1,639,121
New +$4.71M
1
2
3 4 5

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Julian Baker's Q2 2020 Portfolio in Review

As of Q2 2020, Julian Baker held 124 positions worth $22.7B, up 40% from $16.2B the previous quarter. Its ten largest holdings account for 85% of the portfolio.

Julian Baker's Q2 2020 filing shows 14 new, 20 increased, 17 reduced and 10 closed positions. Its largest new stake was Forma Therapeutics Holdings, Inc. Common Stock: 2,000,000 shares worth $93M. The largest sale was Seagen Inc. Common Stock, an estimated $416M.

By sector, the portfolio is most concentrated in Healthcare at 100% of assets, up from 100% a quarter earlier, followed by Financials.

  • Julian Baker's largest Q2 2020 buy was Forma Therapeutics Holdings, Inc. Common Stock: 2,000,000 shares worth $93M.
  • Julian Baker added most to MyoKardia, Inc. Common Stock in Q2 2020, an estimated $116M increase.
  • Julian Baker's biggest Q2 2020 reduction was Seagen Inc. Common Stock, cutting an estimated $416M.
  • Julian Baker fully exited Ra Pharmaceuticals, Inc. Common Stock in Q2 2020, selling an estimated $101M.
  • Julian Baker's ten largest holdings make up 85% of its $22.7B portfolio in Q2 2020.
  • Julian Baker opened 14 new positions and closed 10 in Q2 2020.
  • Julian Baker's portfolio value rose 40% quarter-over-quarter to $22.7B.

Based on Baker Bros. Advisors's 13F filing for Q2 2020, filed 14 Aug 2020.