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JB

Julian Baker Baker Bros. Advisors

AUM $20B
1-Year Est. Return 154.41%
 

Julian Baker is co-managing member of Baker Bros. Advisors, a firm renowned for deep specialization in biotechnology and life sciences. The firm is known for concentrated positions, long holding periods, and scientific diligence that goes well beyond typical generalist research. Baker Bros. filings are closely watched by healthcare investors for signals in clinical-stage and commercial biotech.

This Fund
S&P 500
This Quarter Est. Return
+12.82%
1 Year Est. Return
+154.41%
3 Year Est. Return
+448.58%
5 Year Est. Return
+670.61%
10 Year Est. Return
+4,743.65%
AUM
$13.3B
AUM Growth
+$1.51B
Cap. Flow
+$1.01B
Cap. Flow %
7.58%
Top 10 Hldgs %
83.56%
Holding
124
New
10
Increased
16
Reduced
22
Closed
5

Top Buys

Rank Stock Value
1
ONC
BeOne Medicines Ltd
ONC
+$1.09B
2
MDGL icon
Madrigal Pharmaceuticals
MDGL
+$97.2M
3
SGEN
Seagen Inc. Common Stock
SGEN
+$84.2M
4
KNSA icon
Kiniksa Pharmaceuticals
KNSA
+$54.3M
5
TCDA
Tricida, Inc. Common Stock
TCDA
+$44.7M

Top Sells

Rank Stock Value
1
AVXS
AveXis, Inc. Common Stock
AVXS
+$144M
2
ABLX
Ablynx NV
ABLX
+$119M
3
NKTR icon
Nektar Therapeutics
NKTR
+$29.3M
4
EXEL icon
Exelixis
EXEL
+$13.4M
5
PGNX
Progenics Pharmaceuticals Inc
PGNX
+$10.1M

Sector Composition

Rank Sector Weight
1 Healthcare 99.23%
2 Technology 0.01%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
TCDA
26
DELISTED
Tricida, Inc. Common Stock
TCDA
$47.8M 0.36%
+1,600,000
New +$44.7M
GWPH
27
DELISTED
GW Pharmaceuticals Plc American Depositary Shares
GWPH
$44.9M 0.34%
321,800
+100,000
+45% +$14.2M
ABEO icon
28
Abeona Therapeutics
ABEO
$348M
$35M 0.26%
87,375
– –
PHXM
29
DELISTED
PHAXIAM Therapeutics S.A.. American Depositary Shares
PHXM
$34.5M 0.26%
308,597
-410
-0.1% -$77K
XNCR icon
30
Xencor
XNCR
$2.07B
$32.3M 0.24%
872,072
– –
ECYT
31
DELISTED
Endocyte, Inc. Common Stock
ECYT
$31.4M 0.24%
2,277,799
– –
BLUE
32
DELISTED
bluebird bio
BLUE
$31.4M 0.24%
15,440
– –
BLCM
33
DELISTED
Bellicum Pharmaceuticals, Inc.
BLCM
$30.2M 0.23%
409,345
-5,813
-1% -$453K
NGNE icon
34
Neurogene
NGNE
$773M
$29M 0.22%
546,708
– –
MRUS
35
DELISTED
Merus
MRUS
$26.4M 0.2%
1,160,014
– –
LKFT
36
Lakefront Biotherapeutics American Depositary Shares
LKFT
$1.89B
$24M 0.18%
259,894
– –
QURE icon
37
uniQure
QURE
$3.36B
$22.9M 0.17%
605,000
+105,000
+21% +$3.36M
HALO icon
38
Halozyme
HALO
$12.3B
$21.7M 0.16%
1,283,929
-297,495
-19% -$5.62M
MYOK
39
DELISTED
MyoKardia, Inc. Common Stock
MYOK
$21.5M 0.16%
433,121
+142,857
+49% +$6.92M
SLDB icon
40
Solid Biosciences
SLDB
$997M
$20.9M 0.16%
39,192
– –
ZYME icon
41
Zymeworks
ZYME
$2.05B
$19.4M 0.15%
+1,311,085
New +$20.3M
SGMO
42
DELISTED
SANGAMO THERAPEUTICS INC
SGMO
$18.2M 0.14%
1,283,923
-323,656
-20% -$5.38M
AIMT
43
DELISTED
Aimmune Therapeutics
AIMT
$18.1M 0.14%
673,908
– –
INSM icon
44
Insmed
INSM
$27.5B
$16.6M 0.12%
700,000
– –
CFRX
45
DELISTED
ContraFect Corporation
CFRX
$15.8M 0.12%
8,941
– –
CMTA
46
DELISTED
Clementia Pharmaceuticals Inc.
CMTA
$15.7M 0.12%
1,192,595
+942,595
+377% +$15.3M
BOLD
47
DELISTED
Audentes Therapeutics, Inc
BOLD
$15M 0.11%
393,222
– –
NTLA icon
48
Intellia Therapeutics
NTLA
$1.8B
$15M 0.11%
546,922
-286,873
-34% -$6.95M
SYRE icon
49
Spyre Therapeutics
SYRE
$9.39B
$14.7M 0.11%
55,515
+10,000
+22% +$2.46M
CPRX
50
DELISTED
Catalyst Pharmaceutical
CPRX
$11.3M 0.08%
3,621,962
-759,110
-17% -$2.3M
1
2
3 4 5

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Julian Baker's Q2 2018 Portfolio in Review

As of Q2 2018, Julian Baker held 124 positions worth $13.3B, up 13% from $11.8B the previous quarter. Its ten largest holdings account for 84% of the portfolio.

Julian Baker deployed $1.01B of net new capital in Q2 2018, opening 10 new positions and adding to 16 existing holdings. Its largest new stake was Kiniksa Pharmaceuticals: 3,000,000 shares worth $52M.

By sector, the portfolio is most concentrated in Healthcare at 99% of assets, up from 99% a quarter earlier, followed by Technology.

On the sell side, the largest reduction was Exelixis, an estimated $13.4M trimmed.

  • Julian Baker's largest Q2 2018 buy was Kiniksa Pharmaceuticals: 3,000,000 shares worth $52M.
  • Julian Baker added most to BeOne Medicines Ltd in Q2 2018, an estimated $1.09B increase.
  • Julian Baker's biggest Q2 2018 reduction was Exelixis, cutting an estimated $13.4M.
  • Julian Baker fully exited AveXis, Inc. Common Stock in Q2 2018, selling an estimated $144M.
  • Julian Baker's ten largest holdings make up 84% of its $13.3B portfolio in Q2 2018.
  • Julian Baker opened 10 new positions and closed 5 in Q2 2018.
  • Julian Baker's portfolio value rose 13% quarter-over-quarter to $13.3B.

Based on Baker Bros. Advisors's 13F filing for Q2 2018, filed 14 Aug 2018.