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JB

Julian Baker Baker Bros. Advisors

AUM $20B
1-Year Est. Return 154.41%
 

Julian Baker is co-managing member of Baker Bros. Advisors, a firm renowned for deep specialization in biotechnology and life sciences. The firm is known for concentrated positions, long holding periods, and scientific diligence that goes well beyond typical generalist research. Baker Bros. filings are closely watched by healthcare investors for signals in clinical-stage and commercial biotech.

This Fund
S&P 500
This Quarter Est. Return
+12.1%
1 Year Est. Return
+154.41%
3 Year Est. Return
+448.58%
5 Year Est. Return
+670.61%
10 Year Est. Return
+4,743.65%
AUM
$12.3B
AUM Growth
+$892M
Cap. Flow
+$30.9M
Cap. Flow %
0.25%
Top 10 Hldgs %
85.9%
Holding
130
New
9
Increased
23
Reduced
9
Closed
9

Top Buys

Rank Stock Value
1
ARRY
Array Biopharma Inc
ARRY
+$33.7M
2
ASND icon
Ascendis Pharma A/S
ASND
+$17.1M
3
ONC
BeOne Medicines Ltd
ONC
+$16.8M
4
SAGE
Sage Therapeutics
SAGE
+$15.5M
5
AVXS
AveXis, Inc. Common Stock
AVXS
+$13.5M

Top Sells

Rank Stock Value
1
SGMO
SANGAMO THERAPEUTICS INC
SGMO
+$22.1M
2
AKAO
Achaogen Inc
AKAO
+$17.5M
3
LJPC
La Jolla Pharmaceutical Company
LJPC
+$11.3M
4
BLUE
bluebird bio
BLUE
+$6.47M
5
ARAV
Aravive, Inc. Common Stock
ARAV
+$3.76M

Sector Composition

Rank Sector Weight
1 Healthcare 99.02%
2 Technology 0.01%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
HALO icon
26
Halozyme
HALO
$12.3B
$27.5M 0.22%
1,581,424
– –
CERS icon
27
Cerus
CERS
$566M
$26.6M 0.22%
9,745,209
-496,734
-5% -$1.22M
MRTX
28
DELISTED
Mirati Therapeutics, Inc. Common Stock
MRTX
$26.5M 0.22%
2,269,198
– –
LKFT
29
Lakefront Biotherapeutics American Depositary Shares
LKFT
$1.89B
$26.4M 0.21%
259,894
– –
NTLA icon
30
Intellia Therapeutics
NTLA
$1.8B
$26.4M 0.21%
1,062,120
– –
SAGE
31
DELISTED
Sage Therapeutics
SAGE
$25.3M 0.2%
405,485
+197,157
+95% +$15.5M
CBAY
32
DELISTED
Cymabay Therapeutics
CBAY
$24.1M 0.2%
2,991,775
+1,700,000
+132% +$11.5M
PGNX
33
DELISTED
Progenics Pharmaceuticals Inc
PGNX
$23.2M 0.19%
3,150,808
– –
MRUS
34
DELISTED
Merus
MRUS
$23M 0.19%
1,160,014
– –
ACGN
35
DELISTED
Aceragen Inc
ACGN
$23M 0.19%
75,861
+87
+0.1% +$22.7K
NDRM
36
DELISTED
NeuroDerm Ltd. Ordinary Shares
NDRM
$22.2M 0.18%
571,667
– –
INSM icon
37
Insmed
INSM
$27.5B
$21.8M 0.18%
700,000
+300,000
+75% +$5.71M
IMGN
38
DELISTED
Immunogen Inc
IMGN
$20.6M 0.17%
2,688,489
-326,864
-11% -$2.17M
XNCR icon
39
Xencor
XNCR
$2.07B
$20M 0.16%
872,072
– –
AIMT
40
DELISTED
Aimmune Therapeutics
AIMT
$16.7M 0.14%
673,908
– –
RXDX
41
DELISTED
Ignyta, Inc.
RXDX
$16M 0.13%
1,299,199
+403,199
+45% +$4.16M
MYOK
42
DELISTED
MyoKardia, Inc. Common Stock
MYOK
$15.2M 0.12%
355,264
+255,264
+255% +$8.14M
AERI
43
DELISTED
Aerie Pharmaceuticals
AERI
$14.5M 0.12%
299,356
– –
FOMX
44
DELISTED
Foamix Pharmaceuticals Ltd. Ordinary Shares
FOMX
$13.7M 0.11%
2,466,702
– –
CPRX
45
DELISTED
Catalyst Pharmaceutical
CPRX
$12.9M 0.1%
5,102,153
– –
ACOR
46
DELISTED
Acorda Therapeutics
ACOR
$12.3M 0.1%
+4,329
New +$11.4M
LUMO
47
DELISTED
Lumos Pharma, Inc. Common Stock
LUMO
$10.3M 0.08%
111,919
+56,363
+101% +$4.32M
LGND icon
48
Ligand Pharmaceuticals
LGND
$5.71B
$9.99M 0.08%
117,638
– –
ITCI
49
DELISTED
Intra-Cellular Therapies Inc.
ITCI
$9.61M 0.08%
609,166
– –
LOXO
50
DELISTED
Loxo Oncology, Inc
LOXO
$8.85M 0.07%
96,062
-42,250
-31% -$3.28M
1
2
3 4 5

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Julian Baker's Q3 2017 Portfolio in Review

As of Q3 2017, Julian Baker held 130 positions worth $12.3B, up 7.8% from $11.4B the previous quarter. Its ten largest holdings account for 86% of the portfolio.

Julian Baker's Q3 2017 filing shows 9 new, 23 increased, 9 reduced and 9 closed positions. Its largest new stake was Acorda Therapeutics: 4,329 shares worth $12.3M. The largest sale was SANGAMO THERAPEUTICS INC, an estimated $22.1M.

By sector, the portfolio is most concentrated in Healthcare at 99% of assets, down from 99% a quarter earlier, followed by Technology.

  • Julian Baker's largest Q3 2017 buy was Acorda Therapeutics: 4,329 shares worth $12.3M.
  • Julian Baker added most to Array Biopharma Inc in Q3 2017, an estimated $33.7M increase.
  • Julian Baker's biggest Q3 2017 reduction was SANGAMO THERAPEUTICS INC, cutting an estimated $22.1M.
  • Julian Baker fully exited Zogenix, Inc. in Q3 2017, selling an estimated $2.69M.
  • Julian Baker's ten largest holdings make up 86% of its $12.3B portfolio in Q3 2017.
  • Julian Baker opened 9 new positions and closed 9 in Q3 2017.
  • Julian Baker's portfolio value rose 7.8% quarter-over-quarter to $12.3B.

Based on Baker Bros. Advisors's 13F filing for Q3 2017, filed 14 Nov 2017.