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JB

Julian Baker Baker Bros. Advisors

AUM $20B
1-Year Est. Return 154.41%
 

Julian Baker is co-managing member of Baker Bros. Advisors, a firm renowned for deep specialization in biotechnology and life sciences. The firm is known for concentrated positions, long holding periods, and scientific diligence that goes well beyond typical generalist research. Baker Bros. filings are closely watched by healthcare investors for signals in clinical-stage and commercial biotech.

This Fund
S&P 500
This Quarter Est. Return
+17.28%
1 Year Est. Return
+154.41%
3 Year Est. Return
+448.58%
5 Year Est. Return
+670.61%
10 Year Est. Return
+4,743.65%
AUM
$11B
AUM Growth
+$1.48B
Cap. Flow
-$1.03B
Cap. Flow %
-9.36%
Top 10 Hldgs %
83.4%
Holding
140
New
7
Increased
14
Reduced
16
Closed
6

Sector Composition

Rank Sector Weight
1 Healthcare 88.07%
2 Technology 0.01%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
XNCR icon
26
Xencor
XNCR
$2.07B
$21.4M 0.19%
872,072
HALO icon
27
Halozyme
HALO
$12.3B
$20.9M 0.19%
1,731,057
-107,000
-6% -$1.09M
ACHN
28
DELISTED
Achillion Pharmaceuticals
ACHN
$20.1M 0.18%
2,475,515
BLUE
29
DELISTED
bluebird bio
BLUE
$19.9M 0.18%
22,692
MRUS
30
DELISTED
Merus
MRUS
$19.4M 0.18%
1,160,014
+37,155
+3% +$353K
SGMO
31
DELISTED
SANGAMO THERAPEUTICS INC
SGMO
$18.8M 0.17%
4,055,876
NTLA icon
32
Intellia Therapeutics
NTLA
$1.8B
$18.1M 0.16%
1,062,120
ACGN
33
DELISTED
Aceragen Inc
ACGN
$18M 0.16%
51,625
+96
+0.2% +$25.4K
DSCI
34
DELISTED
Derma Sciences, Inc. Common Stock (DE)
DSCI
$17.5M 0.16%
3,752,390
LKFT
35
Lakefront Biotherapeutics American Depositary Shares
LKFT
$1.89B
$16.8M 0.15%
259,894
TGTX icon
36
TG Therapeutics
TGTX
$8.31B
$15.5M 0.14%
2,003,991
MRTX
37
DELISTED
Mirati Therapeutics, Inc. Common Stock
MRTX
$15M 0.14%
2,269,198
ASND icon
38
Ascendis Pharma A/S
ASND
$16.6B
$15M 0.14%
745,521
ARWR icon
39
Arrowhead Research
ARWR
$12.3B
$13.6M 0.12%
1,856,967
+847,458
+84% +$5.49M
VTAE
40
DELISTED
VITAE PHARMACEUTICALS INC COMMON STOCK
VTAE
$13.3M 0.12%
637,597
ALKS icon
41
Alkermes
ALKS
$8.11B
$11.8M 0.11%
250,251
ZGNX
42
DELISTED
Zogenix, Inc.
ZGNX
$11.4M 0.1%
1,000,000
AERI
43
DELISTED
Aerie Pharmaceuticals
AERI
$11.3M 0.1%
299,356
DERM
44
DELISTED
Dermira, Inc.
DERM
$11M 0.1%
326,428
AGIO icon
45
Agios Pharmaceuticals
AGIO
$1.98B
$11M 0.1%
207,915
MGNX icon
46
MacroGenics
MGNX
$261M
$10.9M 0.1%
363,676
AIMT
47
DELISTED
Aimmune Therapeutics
AIMT
$10.1M 0.09%
673,908
CFRX
48
DELISTED
ContraFect Corporation
CFRX
$10M 0.09%
+5,057
New +$9.93M
DMTX
49
DELISTED
Dimension Therapeutics, Inc
DMTX
$10M 0.09%
1,251,881
SAGE
50
DELISTED
Sage Therapeutics
SAGE
$9.59M 0.09%
208,328
-15,720
-7% -$640K

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Julian Baker's Q3 2016 Portfolio in Review

As of Q3 2016, Julian Baker held 140 positions worth $11B, up 16% from $9.54B the previous quarter. Its ten largest holdings account for 83% of the portfolio.

Julian Baker withdrew a net $1.03B in Q3 2016, closing 6 positions and reducing 16 holdings. Its most notable exit was XENOPORT, INC., an estimated $24.5M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 88% of assets, up from 86% a quarter earlier, followed by Technology.

Against the trend, Julian Baker opened a new position in ContraFect Corporation worth $10M.

  • Julian Baker's largest Q3 2016 buy was ContraFect Corporation: 5,057 shares worth $10M.
  • Julian Baker added most to Amarin Corp in Q3 2016, an estimated $55.6M increase.
  • Julian Baker's biggest Q3 2016 reduction was BioCryst Pharmaceuticals, cutting an estimated $16.2M.
  • Julian Baker fully exited XENOPORT, INC. in Q3 2016, selling an estimated $24.5M.
  • Julian Baker's ten largest holdings make up 83% of its $11B portfolio in Q3 2016.
  • Julian Baker opened 7 new positions and closed 6 in Q3 2016.
  • Julian Baker's portfolio value rose 16% quarter-over-quarter to $11B.

Based on Baker Bros. Advisors's 13F filing for Q3 2016, filed 14 Nov 2016.