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JB

Julian Baker Baker Bros. Advisors

AUM $20B
1-Year Est. Return 154.41%
 

Julian Baker is co-managing member of Baker Bros. Advisors, a firm renowned for deep specialization in biotechnology and life sciences. The firm is known for concentrated positions, long holding periods, and scientific diligence that goes well beyond typical generalist research. Baker Bros. filings are closely watched by healthcare investors for signals in clinical-stage and commercial biotech.

This Fund
S&P 500
This Quarter Est. Return
-21.22%
1 Year Est. Return
+154.41%
3 Year Est. Return
+448.58%
5 Year Est. Return
+670.61%
10 Year Est. Return
+4,743.65%
AUM
$9.48B
AUM Growth
-$2.59B
Cap. Flow
-$1.26B
Cap. Flow %
-13.32%
Top 10 Hldgs %
78.76%
Holding
139
New
5
Increased
29
Reduced
8
Closed
5

Top Buys

Rank Stock Value
1
INCY icon
Incyte
INCY
+$300M
2
SGEN
Seagen Inc. Common Stock
SGEN
+$200M
3
ACAD icon
Acadia Pharmaceuticals
ACAD
+$81.4M
4
ANAC
ANACOR PHARMACEUTICALS INC COM
ANAC
+$68.2M
5
BMRN icon
BioMarin Pharmaceuticals
BMRN
+$56.3M

Top Sells

Rank Stock Value
1
DYAX
DYAX CORPORATION
DYAX
+$313M
2
GILD icon
Gilead Sciences
GILD
+$25.3M
3
MDVN
MEDIVATION, INC.
MDVN
+$12M
4
CPRX
Catalyst Pharmaceutical
CPRX
+$4.31M
5
IOVA icon
Iovance Biotherapeutics
IOVA
+$4.11M

Sector Composition

Rank Sector Weight
1 Healthcare 82.24%
2 Technology 0%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
INSM icon
26
Insmed
INSM
$27.5B
$19M 0.2%
1,500,000
+500,000
+50% +$6.57M
PGNX
27
DELISTED
Progenics Pharmaceuticals Inc
PGNX
$19M 0.2%
4,350,808
– –
HALO icon
28
Halozyme
HALO
$12.3B
$18.3M 0.19%
1,931,057
– –
TGTX icon
29
TG Therapeutics
TGTX
$8.31B
$17.1M 0.18%
2,003,991
– –
ITCI
30
DELISTED
Intra-Cellular Therapies Inc.
ITCI
$16.9M 0.18%
609,166
– –
XNPT
31
DELISTED
XENOPORT, INC.
XNPT
$15.7M 0.17%
3,475,672
– –
MDVN
32
DELISTED
MEDIVATION, INC.
MDVN
$15.2M 0.16%
329,876
-329,876
-50% -$12M
BLUE
33
DELISTED
bluebird bio
BLUE
$15M 0.16%
27,247
+16,354
+150% +$10M
FOMX
34
DELISTED
Foamix Pharmaceuticals Ltd. Ordinary Shares
FOMX
$14.6M 0.15%
2,241,702
+194,735
+10% +$1.26M
ACGN
35
DELISTED
Aceragen Inc
ACGN
$13.8M 0.15%
51,450
+52
+0.1% +$13.9K
ARRY
36
DELISTED
Array Biopharma Inc
ARRY
$12.7M 0.13%
4,310,666
– –
LKFT
37
Lakefront Biotherapeutics American Depositary Shares
LKFT
$1.89B
$12.7M 0.13%
303,394
-65,882
-18% -$3.06M
AGIO icon
38
Agios Pharmaceuticals
AGIO
$1.98B
$12.5M 0.13%
307,915
+207,915
+208% +$8.89M
NVAX icon
39
Novavax
NVAX
$1.47B
$12.3M 0.13%
118,963
+9,179
+8% +$985K
XNCR icon
40
Xencor
XNCR
$2.07B
$11.7M 0.12%
872,072
– –
DSCI
41
DELISTED
Derma Sciences, Inc. Common Stock (DE)
DSCI
$11.6M 0.12%
3,752,390
– –
OMER icon
42
Omeros
OMER
$1.39B
$11.5M 0.12%
749,250
+413,024
+123% +$5.02M
EXEL icon
43
Exelixis
EXEL
$13.4B
$10.3M 0.11%
+2,580,000
New +$10.9M
DMTX
44
DELISTED
Dimension Therapeutics, Inc
DMTX
$9.8M 0.1%
1,251,881
+17,400
+1% +$137K
GBT
45
DELISTED
Global Blood Therapeutics, Inc.
GBT
$9.52M 0.1%
600,000
+200,000
+50% +$3.55M
ASND icon
46
Ascendis Pharma A/S
ASND
$16.6B
$9.38M 0.1%
505,521
– –
ZGNX
47
DELISTED
Zogenix, Inc.
ZGNX
$9.24M 0.1%
1,000,000
– –
ARCT icon
48
Arcturus Therapeutics
ARCT
$382M
$8.86M 0.09%
333,766
– –
ALKS icon
49
Alkermes
ALKS
$8.11B
$8.56M 0.09%
250,251
– –
ATYR
50
aTyr Pharma
ATYR
$49.2M
$8.42M 0.09%
152,686
-14,109
-8% -$1.07M
1
2
3 4 5

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Julian Baker's Q1 2016 Portfolio in Review

As of Q1 2016, Julian Baker held 139 positions worth $9.48B, down 21% from $12.1B the previous quarter. Its ten largest holdings account for 79% of the portfolio.

Julian Baker withdrew a net $1.26B in Q1 2016, closing 5 positions and reducing 8 holdings. Its most notable exit was DYAX CORPORATION, an estimated $313M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 82% of assets, up from 79% a quarter earlier, followed by Technology.

Against the trend, Julian Baker opened a new position in BeOne Medicines Ltd worth $56.1M.

  • Julian Baker's largest Q1 2016 buy was BeOne Medicines Ltd: 1,912,680 shares worth $56.1M.
  • Julian Baker added most to Incyte in Q1 2016, an estimated $300M increase.
  • Julian Baker's biggest Q1 2016 reduction was MEDIVATION, INC., cutting an estimated $12M.
  • Julian Baker fully exited DYAX CORPORATION in Q1 2016, selling an estimated $313M.
  • Julian Baker's ten largest holdings make up 79% of its $9.48B portfolio in Q1 2016.
  • Julian Baker opened 5 new positions and closed 5 in Q1 2016.
  • Julian Baker's portfolio value fell 21% quarter-over-quarter to $9.48B.

Based on Baker Bros. Advisors's 13F filing for Q1 2016, filed 16 May 2016.